Recommendations for managing missing data, attrition and response shift in palliative and end-of-life care research: Part of the MORECare research method guidance on statistical issues

Palliative Medicine

Volumn 27, Issue 10, 2013, Pages 899-907

  Preston, Nancy J ^a   Fayers, Peter ^b   Walters, Stephen J ^c   Pilling, Mark ^d   Grande, Gunn E ^d   Short, Vicky ^d   Owen Jones, Eleanor ^d   Evans, Catherine J ^e   Benalia, Hamid ^e   Higginson, Irene J ^e   Todd, Chris J ^d  

^a LANCASTER UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

consensus; palliative care; research design; Statistics

Indexed keywords

ARTICLE; CLINICAL ARTICLE; CONSENSUS; CONSULTATION; HUMAN; MEDICAL RESEARCH; PALLIATIVE THERAPY; SCIENTIST; STATISTICAL ANALYSIS; STATISTICS; TAXONOMY; TERMINAL CARE; WORKSHOP;

CONSENSUS; PALLIATIVE CARE; RESEARCH DESIGN; STATISTICS;

DATA COLLECTION; HEALTH SERVICES RESEARCH; HUMANS; PALLIATIVE CARE; TERMINAL CARE;

EID: 84885813399     PISSN: 02692163     EISSN: 1477030X     Source Type: Journal    
DOI: 10.1177/0269216313486952     Document Type: Article

References (24)

1. Guideline on missing data in confirmatory clinical trials. London: European Medicines Agency ; 2010 :
2. Addington-Hall JM, MacDonald LD, Anderson HR, et al. Randomised controlled trial of coordinating care for terminally ill cancer patients. BMJ. 1992 ; 305: 1317-1322
3. McCorkle R, Benoliel JQ, Donaldson G, et al. A randomized clinical trial of home nursing care for lung cancer patients. Cancer. 1989 ; 64: 1375-1382
4. Temel JS, Greer JA, Muzikansky A, et al. Early palliative care for patients with metastatic non-small-cell lung cancer. N Engl J Med. 2010 ; 363: 733-742
5. Schulz KF, Grimes DA. Sample size slippages in randomised trials: exclusions and the lost and wayward. Lancet. 2002 ; 359: 781-785
6. Sackett DL, Richardson WS, Rosenberg W, et al Evidence based medicine: how to practice and teach EBM. New York: Churchill Livingstone ; 1997 :
7. Allison PD Missing data. Thousand Oaks, CA: SAGE ; 1994 :
8. Bordeleau L, Szalai JP, Ennis M, et al. Quality of life in a randomized trial of group psychosocial support in metastatic breast cancer: overall effects of the intervention and an exploration of missing data. J Clin Oncol. 2003 ; 21 (10). 1944-1951
9. Rubin DB Multiple imputation for non-response in surveys. New York: John Wiley & Sons ; 1987 :
10. Schwartz C, Sprangers MAG, Fayers PM Assessing quality of life in clinical trials: methods and practice. 2 nd ed.Oxford: Oxford University Press, 2005, pp. 275-290. Fayers PM Hays RD, ed. Oxford: Oxford University Press ; 2005: 275-290.
11. Higginson IJ, Evans CJ, Grande G, et al. Evaluating complex interventions in End of Life Care: the MORECare Statement on good practice 4 generated by a synthesis of transparent expert consultations and systematic reviews. BMC Medicine. 2013 ;:
12. Gysels M, Evans C, Lewis P, et al. MORECare research methods guidance development: Recommendations for ethical issues in palliative and end-of-life care research. Palliat Med. 2013 ; 27: 908-917
13. Evans CJ, Benalia H, Preston N, et al. The selection and use of outcome measures in palliative and end-of-life care research: the MORECare international consensus workshop. Journal of Pain and Symptom Management. :
14. Farquhar MC, Preston N, Short V, et al. MORECare Research Methods Guidance Development: Recommendations for Using Mixed Methods to Develop and Evaluate Complex Interventions in Palliative and End of Life Care. Palliat Med. 2012 ; 26: 419
15. Preston N, Short V, Hollingworth W, et al. MORECare research methods guidance development: recommendations for health economic evaluations in palliative and end of life care research. Palliat Med. 2012 ; 26: 541
16. Yardley L, Beyer N, Hauer K, et al. Recommendations for promoting the engagement of older people in activities to prevent falls. Qual Saf Health Care. 2007 ; 16: 230-234
17. National cancer control programmes: policies and managerial guidelines, 2002 guidelines. 2002 guidelines. 2nd ed.Geneva: World Health Organization, 2002. Geneva: World Health Organization ; 2002 :
18. End-of-life care strategy: promoting high quality care for all adults at end of life. London: HMSO ; 2008 :
19. Raine R, Sanderson C, Black N. Developing clinical guidelines: a challenge to current methods. BMJ. 2005 ; 331: 631-633
20. US Food and Drug Administration (FDA). Guidance for industry: E9 statistical principles for clinical trials, http://www.fda.gov/downloads/Drugs/ GuidanceComplianceRegulatoryInformation/Guidances/UCM073137.pdfp34
21. CarpenterJBartlettJKenwardM. missingdata.org.uk. http://www.missingdata. org.uk (2012, accessed 21 June 2012).
22. Van BuurenS. Multipele Imputatie in Vogelvlucht. STAtOR2012; 13: 10-15 (English translation of Figure 1 is available at: http://www.stefvanbuuren.nl/ mi/index.html).
23. Van BuurenS. Flexible imputation of missing data. Appendix A: software for multiple imputation, http://www.stefvanbuuren.nl/mi/Software.html (2012, accessed April 2013).
24. Fayers PM, Langston AL, Robertson C. Implicit self-comparisons against others could bias quality of life assessments. J Clin Epidemiol. 2007 ; 60: 1034-1039