The spectrum of optic disc ischemia in patients younger than 50 years

Transactions of the American Ophthalmological Society

Volumn 111, Issue , 2013, Pages 93-118

  Arnold, Anthony C ^a   Costa, Roberta M S ^a   Dumitrascu, Oana M ^a  

^a JULES STEIN EYE INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGE DISTRIBUTION; ANEMIA; ANTERIOR ISCHEMIC OPTIC NEUROPATHY; BLIND SPOT ENLARGEMENT; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; CROWDED OPTIC DISC; DELAYED OPTIC DISC FILLING; DIABETIC PAPILLOPATHY; DIABETIC RETINOPATHY; DIALYSIS; DISEASE COURSE; DISEASE SEVERITY; EYE BLOOD FLOW; EYE DISEASE; FEMALE; FLAME HEMORRHAGE; FLUORESCENCE ANGIOGRAPHY; FOLLOW UP; HUMAN; HYPERTENSION; ISCHEMIC OPTIC NEUROPATHY; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MIGRAINE; OPTIC DISC EDEMA; OPTIC DISC ISCHEMIA; OPTIC NERVE ATROPHY; PATHOPHYSIOLOGY; PERIPAPILLARY CHOROIDAL FILLING DELAY; PHOTOPSIA; PRIORITY JOURNAL; RECURRENT DISEASE; RETINA MACULA CYSTOID EDEMA; RETROSPECTIVE STUDY; REVIEW; RISK FACTOR; VISUAL ACUITY; VISUAL FIELD DEFECT; VISUAL IMPAIRMENT;

ADOLESCENT; ADULT; DISEASE PROGRESSION; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; KAPLAN-MEIER ESTIMATE; KIDNEY FAILURE, CHRONIC; LOGISTIC MODELS; MALE; MIDDLE AGED; OPTIC NEUROPATHY, ISCHEMIC; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 84885813033     PISSN: None     EISSN: 15456110     Source Type: Journal    
DOI: None     Document Type: Review

References (85)

1. Arnold AC. Ischemic optic neuropathy. In: Miller NR, Newman NJ, eds. Walsh & Hoyt's Clinical Neuro-Ophthalmology. Vol 1. 6th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005:349-384.
2. Spencer WH, Hoyt WF. A fatal case of giant-cell arteritis (temporal or cranial arteritis) with ocular involvement. Arch Ophthalmol 1960;64(6):862-867.
3. MacFaul PA. Ciliary artery involvement in giant cell arteritis. Br J Ophthalmol 1967;51(8):505-512.
4. Henkind P, Charles NC, Pearson J. Histopathology of ischemic optic neuropathy. Am J Ophthalmol 1970;69(1):78-90.
5. Knox DL, Duke JR. Slowly progressive ischemic optic neuropathy. A clinicopathologic case report. Trans Am Acad Ophthalmol Otolaryngol 1971;75(5):1065-1068.
6. Lieberman MF, Shahi A, Green WR. Embolic ischemic optic neuropathy. Am J Ophthalmol 1978;86(2):206-210.
7. Rootman J, Butler D. Ischaemic optic neuropathy-a combined mechanism. Br J Ophthalmol 1980;64(11):826-831.
8. Quigley HA, Miller NR, Green WR. The pattern of optic nerve fiber loss in anterior ischemic optic neuropathy. Am J Ophthalmol 1985;100(6):769-776.
9. Levin LA, Louhab A. Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy. Arch Ophthalmol 1996;114(4):488-491.
10. Tesser RA, Niendorf ER, Levin LA. The morphology of an infarct in nonarteritic anterior ischemic optic neuropathy. Ophthalmology 2003;110(10):2031-2035.
11. Knox DL, Kerrison JB, Green WR. Histopathologic studies of ischemic optic neuropathy. Trans Am Ophthalmol Soc 2000;98:203-222.
12. Flaharty PM, Sergott RC, Lieb W, Bosley TM, Savino PJ. Optic nerve sheath decompression may improve blood flow in anterior ischemic optic neuropathy. Ophthalmology 1993;100(3):297-302.
13. Hayreh SS, Beach KW. [Discussion of: Flaharty PM, Sergott RC, Lieb W, Bosley TM, Savino PJ. Optic nerve sheath decompression may improve blood flow in anterior ischemic optic neuropathy]. Ophthalmology 1993;100(3):303-305.
14. Arnold AC. Pathogenesis of nonarteritic anterior ischemic optic neuropathy. J Neuro-Ophthalmol 2003;23(2):157-163.
15. Eagling EM, Sanders MD, Miller SJH. Ischaemic papillopathy. Clinical and fluorescein angiographic review of forty cases. Br J Ophthalmol 1974;58(12):990-1008.
16. Hayreh SS. Anterior ischemic optic neuropathy. II. Fundus on ophthalmoscopy and fluorescein angiography. Br J Ophthalmol 1974;58(12):964-980.
17. Arnold AC, Hepler RS. Fluorescein angiography in acute anterior ischemic optic neuropathy. Am J Ophthalmol 1994;117(2):222-230.
18. Mack HG, O'Day J, Currie JN. Delayed choroidal perfusion in giant cell arteritis. J Clin Neuro-Ophthalmol 1991;11(4):221-227.
19. Siatkowski RM, Gass JDM, Glaser JS, et al. Fluorescein angiography in the diagnosis of giant cell arteritis. Am J Ophthalmol 1993;115(1):57-63.
20. Arnold AC, Badr M, Hepler RS. Fluorescein angiography in nonischemic optic disc edema. Arch Ophthalmol 1996;114(3):293-298.
21. Feit RH, Tomsak RL, Ellenberger C. Structural factors in the pathogenesis of ischemic optic neuropathy. Am J Ophthalmol 1984;98(1):105-108.
22. Beck RW, Savino PJ, Repka MX, Schatz NJ, Sergott RC. Optic disc structure in anterior ischemic optic neuropathy. Ophthalmology 1984;91(11):1334-1337.
23. Doro S, Lessell S. Cup-disc ratio and ischemic optic neuropathy. Arch Ophthalmol 1985;103(8):1143-1144.
24. Burde RM. Optic disk risk factors for nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol 1993;116(6):759-764.
25. Boghen DR, Glaser JS. Ischaemic optic neuropathy. The clinical profile and natural history. Brain 1975;98(4):689-708.
26. Repka MX, Savino PJ, Schatz NJ, Sergott RC. Clinical profile and long-term implications of anterior ischemic optic neuropathy. Am J Ophthalmol 1983;96(4):478-483.
27. Guyer DR, Miller NR, Auer CL, Fine SL. The risk of cerebrovascular and cardiovascular disease in patients with anterior ischemic optic neuropathy. Arch Ophthalmol 1985;103(8):1136-1142.
28. Ischemic Optic Neuropathy Decompression Trial Research Group. Characteristics of patients with nonarteritic anterior ischemic optic neuropathy eligible for the Ischemic Optic Neuropathy Decompression Trial. Arch Ophthalmol 1996;114(11):1366-1374.
29. Hayreh SS, Joos KM, Podhajsky PA, Long CR. Systemic diseases associated with nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol 1994;118(6):766-780.
30. Jacobson DM, Vierkant RA, Belongia EA. Nonarteritic anterior ischemic optic neuropathy. A case-control study of potential risk factors. Arch Ophthalmol 1997;115(11):1403-1407.
31. Salomon O, Huna-Baron R, Kurtz S, et al. Analysis of prothrombotic and vascular risk factors in patients with nonarteritic anterior ischemic optic neuropathy. Ophthalmology 1999;106(4):739-742.
32. Giuffre G. Hematological risk factors for anterior ischemic optic neuropathy. Neuro-Ophthalmology 1990;10(4):197-203.
33. Talks SJ, Chong NH, Gibson JM, et al. Fibrinogen, cholesterol, and smoking as risk factors for non-arteritic anterior ischaemic optic neuropathy. Eye 1995;9(1):85-88.
34. Chung SM, Gay CA, McCrary JA. Nonarteritic anterior ischemic optic neuropathy. The impact of tobacco use. Ophthalmology 1994;101(4):779-782.
35. Deramo VA, Sergott RC, Augsburger JJ, Foroozan R, Savino PJ, Leone A. Ischemic optic neuropathy as the first manifestation of elevated cholesterol levels in young patients. Ophthalmology 2003;110(5):1041-1045.
36. Biousse V, Kerrison JB, Newman NJ. Is non-arteritic anterior ischaemic optic neuropathy related to homocysteine? Br J Ophthalmol 2000;84(5):554.
37. Pianka P, Almog Y, Man O, et al. Hyperhomocystinemia in patients with nonarteritic anterior ischemic optic neuropathy, central retinal artery occlusion, and central retinal vein occlusion. Ophthalmology 2000;107(8):1588-1592.
38. Salomon O, Rosenberg N, Steinberg DM, et al. Nonarteritic anterior ischemic optic neuropathy is associated with a specific platelet polymorphism located on the glycoprotein Ibalpha gene. Ophthalmology 2004 Jan;111(1):184-188.
39. Weinstein JM, Feman SS. Ischemic optic neuropathy in migraine. Arch Ophthalmol 1982;100(7):1097-1100.
40. Katz B, Bamford CR. Migrainous ischemic optic neuropathy. Neurology 1985;35(1):112-114.
41. Hayreh SS, Podhajsky PA, Zimmerman B. Ipsilateral recurrence of nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol 2001;132(5):734-742.
42. Beri M, Klugman MR, Kohler JA, Hayreh SS. Anterior ischemic optic neuropathy. VII. Incidence of bilaterality and various influencing factors. Ophthalmology 1987;94(8):1020-1028.
43. Hayreh SS. Anterior ischemic optic neuropathy. Differentiation of arteritic from non-arteritic type and its management. Eye 1990;4(1):25-41.
44. Boone MI, Massry GG, Frankel RA, et al. Visual outcome in bilateral nonarteritic anterior ischemic optic neuropathy. Ophthalmology 1996;103(10):1223-1228.
45. WuDunn D, Zimmerman K, Sadun AA, et al. Comparison of visual function in fellow eyes after bilateral nonarteritic anterior ischemic optic neuropathy. Ophthalmology 1997;104(1):104-111.
46. Beck RW, Hayreh SS, Podhajsky PA, Tan ES, Moke PS. Aspirin therapy in nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol 1997;123(2):212-217.
47. Newman NJ, Scherer R, Langenberg P, et al. The fellow eye in NAION: report from the ischemic optic neuropathy decompression trial follow-up study. Am J Ophthalmol 2002;134(3):317-328.
48. Lavin PJM, Ellenberger C. Recurrent ischemic optic neuropathy. Neuro-Ophthalmology 1983;3(3):193-198.
49. Beck RW, Savino PJ, Schatz NJ, Smith CH, Sergott RC. Anterior ischaemic optic neuropathy. Recurrent episodes in the same eye. Br J Ophthalmol 1983;67(10):705-709.
50. Borchert M, Lessell S. Progressive and recurrent nonarteritic anterior ischemic optic neuropathy. Am J Ophthalmol 1988;106(4):443-449.
51. Dutton JJ, Burde RM. Anterior ischemic optic neuropathy of the young. J Clin Neuro-Ophthalmol 1983;3(2):137-146.
52. Hamed LM, Purvin V, Rosenberg M. Recurrent anterior ischemic optic neuropathy in young adults. J Clin Neuro-Ophthalmol 1988;8(4):239-246.
53. Josef JM, Burde RM. Ischemic optic neuropathy of the young. J Clin Neuro-Ophthalmol 1988;8(4):247-248.
54. Janaky M, Fulop Z, Palffy A, Benedek K, Benedek G. Non-arteritic ischaemic optic neuropathy (NAION) in patients under 50 years of age. Acta Ophthalmol Scand 2005;83(4):499-503.
55. Preechawat P, Bruce BB, Newman NJ, Biousse V. Anterior ischemic optic neuropathy in patients younger than 50 years. Am J Ophthalmol 2007;144(6):953-960.
56. Servilla KS, Groggel GC. Anterior ischemic optic neuropathy as a complication of hemodialysis. Am J Kidney Dis 1986;8(1):61-63.
57. Hamed LM, Winward KE, Glaser JS, et al. Optic neuropathy in uremia. Am J Ophthalmol 1989;108(1):30-35.
58. Michaelson C, Behrens M, Odel J. Bilateral anterior ischaemic optic neuropathy associated with optic disc drusen and systemic hypotension. Br J Ophthalmol 1989;73(9):762-764.
59. Haider S, Astbury NJ, Hamilton DV. Optic neuropathy in uraemic patients on dialysis. Eye 1993;7(1):148-151.
60. Connolly SE, Gordon KB, Horton JC. Salvage of vision after hypotension-induced ischemic optic neuropathy. Am J Ophthalmol 1994;117(2):235-242.
61. Knox DL, Hanneken AM, Hollows FC, et al. Uremic optic neuropathy. Arch Ophthalmol 1988;106(1):50-54.
62. Saini JS, Jain IS, Dhar S, et al. Uremic optic neuropathy. J Clin Neuro-Ophthalmol 1989;9(2):131-133.
63. Taylor D, Ramsay J, Day S, et al. Infarction of the optic nerve head in children with accelerated hypertension. Br J Ophthalmol 1981;65(3):153-160.
64. Hayreh SS. Anterior ischemic optic neuropathy. VIII. Clinical features and pathogenesis of post-hemorrhagic amaurosis. Ophthalmology 1987;94(11):1488-1502.
65. Johnson MW, Kincaid MC, Trobe JD. Bilateral optic nerve infarctions after blood loss and hypotension. Ophthalmology 1987;94(12):1577-1584.
66. Hayreh SS. Anterior ischemic optic neuropathy V. Optic disc edema as an early sign. Arch Ophthalmol 1981;99(6):1030-1040.
67. Gordon RN, Burde RM, Slamovits T. Asymptomatic optic disc edema. J Neuro-Ophthalmol 1997;17(1):29-32.
68. Prenner JL, Sharma A, Ibarra MS, Maguire AM, Volpe NJ. Prolonged premonitory optic disc signs in anterior ischemic optic neuropathy. J Neuro-Ophthalmol 2002;22(2):110-112.
69. Almog Y, Goldstein M. Visual outcome in eyes with asymptomatic optic disc edema. J Neuro-Ophthalmol 2003;23(3):204-207.
70. Hayreh SS, Zimmerman MB. Incipient nonarteritic anterior ischemic optic neuropathy. Ophthalmology 2007;114(9):1763-1772.
71. Lubow M, Makley TA. Pseudopapilledema of juvenile diabetes mellitus. Arch Ophthalmol 1971;85(4):417-422.
72. Appen RE, Chandra SR, Klein R, Myers FL. Diabetic papillopathy. Am J Ophthalmol 1980;90(2):203-209.
73. Barr CC, Glaser JS, Blankenship G. Acute disc swelling in juvenile diabetes. Clinical profile and natural history of 12 cases. Arch Ophthalmol 1980;98(12):2185-2192.
74. Pavan PR, Aiello LM, Wafai MZ, Briones JC, Sebestyen JG, Bradbury MJ. Optic disc edema in juvenile-onset diabetes. Arch Ophthalmol 1980;98(12):2193-2195.
75. Hayreh SS, Zahoruk RM. Anterior ischemic optic neuropathy. VI. In juvenile diabetics. Ophthalmologica 1981;182(1):13-28.
76. Regillo CD, Brown GC, Savino PJ, et al. Diabetic papillopathy. Patient characteristics and fundus findings. Arch Ophthalmol 1995;113(7):889-895.
77. Smith JL. Pseudohemangioma of the optic disc following ischemic optic neuropathy. J Clin Neuro-Ophthalmol 1985;5(2):81-89.
78. Hayreh SS, Zimmerman MB. Nonateritic anterior ischemic optic neuropathy: clinical characteristics in diabetic patients versus nondiabetic patients. Ophthalmology 2008;115(10):1818-1825.
79. Rizzo JF III, Lessell S. Optic neuritis and ischemic optic neuropathy. Overlapping clinical profiles. Arch Ophthalmol 1991;109(9):1668-1672.
80. Rizzo JF III, Andreoli CM, Rabinov JD. Use of magnetic resonance imaging to differentiate optic neuritis and nonarteritic anterior ischemic optic neuropathy. Ophthalmology 2002;109(9):1679-1684.
81. Logan JFJ, Chakravarthy U, Hughes AE, Patterson CC, Jackson JA, Rankin SJA. Evidence for association of endothelial nitric oxide synthase gene in subjects with glaucoma and a history of migraine. Invest Ophthalmol Vis Sci 2005;46(9):3221-3226.
82. Katz B. Bilateral sequential migrainous ischemic optic neuropathy. Am J Ophthalmol 1985;99(4):489.
83. Jonas JB, Gabriele GC, Naumann GOH. Anterior ischemic optic neuropathy: nonarteritic form in small and giant cell arteritis in normal sized optic discs. Int Ophthalmol 1988;12(2):119-125.
84. Kline LB. Progression of visual defects in ischemic optic neuropathy. Am J Ophthalmol 1988;106(2):199-203.
85. Sergott RC, Cohen MS, Bosley TM, Savino PJ. Optic nerve sheath decompression may improve the progressive form of ischemic optic neuropathy. Arch Ophthalmol 1989;107(12):1743-1754.