Symptom improvement after helicobacter pylori eradication in patients with functional dyspepsia-A multicenter, randomized, prospective cohort study

International Journal of Clinical and Experimental Medicine

Volumn 6, Issue 9, 2013, Pages 747-756

  Xu, Sanping ^a   Wan, Xueming ^a   Zheng, Xiaolan ^a   Zhou, Yali ^b   Song, Zhiqiang ^b   Cheng, Minghu ^c   Du, Yiqi ^d   Hou, Xiaohua ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b PEKING UNIVERSITY PEOPLE S HOSPITAL   (China)

^c SUN YAT SEN UNIVERSITY   (China)

^d SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Epigastric pain syndrome; Functional dyspepsia; Helicobacter pylori eradication; Helicobacter pylori infection; Postprandial distress syndrome; Sequential therapy; Triple therapy

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; DOMPERIDONE; ESOMEPRAZOLE; HYDROTALCITE; TINIDAZOLE;

ADULT; AGED; ARTICLE; BACTERIAL CLEARANCE; COHORT ANALYSIS; CONTROLLED STUDY; DISTRESS SYNDROME; DRUG EFFICACY; DRUG RESPONSE; DYSPEPSIA; EPIGASTRIC PAIN; FEMALE; GASTROINTESTINAL SYMPTOM; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; POSTPRANDIAL DISTRESS SYNDROME; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TREATMENT DURATION;

EID: 84885803680     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Sanders MK and Peura DA. Helicobacter pylori-Associated Diseases. Curr Gastroenterol Rep 2002; 4: 448-454.
2. McColl K, Murray L, El-Omar E, Dickson A, El-Nujumi A, Wirz A, Kelman A, Penny C, Knill-Jones R and Hilditch T. Symptomatic benefit from eradicating Helicobacter pylori infection in patients with nonulcer dyspepsia. N Engl J Med 1998; 339: 1869-1874.
3. Blum AL, Talley NJ, O'Morain C, van Zanten SV, Labenz J, Stolte M, Louw JA, Stubberod A, The-odors A, Sundin M, Bolling-Sternevald E and Junghard O. Lack of effect of treating Helicobacter pylori infection in patients with nonulcer dyspepsia. Omeprazole plus Clarithromycin and Amoxicillin Effect One Year after Treatment (OCAY) Study Group. N Engl J Med 1998; 339: 1875-1881.
4. Everhart JE. Recent developments in the epidemiology of Helicobacter pylori. Gastroenterol Clin North Am 2000; 29: 559-578.
5. Lacy BE and Rosemore J. Helicobacter pylori: ulcers and more: the beginning of an era. J Nutr 2001; 131: 2789S-2793S.
6. Armstrong D. Helicobacter pylori infection and dyspepsia. Scand J Gastroenterol Suppl 1996; 215: 38-47.
7. Schubert TT, Schubert AB and Ma CK. Symptoms, gastritis, and Helicobacter pylori in patients referred for endoscopy. Gastrointest Endosc 1992; 38: 357-360.
8. Tack J, Talley NJ, Camilleri M, Holtmann G, Hu P, Malagelada JR and Stanghellini V. Functional gastroduodenal disorders. Gastroenterology 2006; 130: 1466-1479.
9. Zolezzi Francis A. [Functional gastrointestinal diseases and Rome III]. Rev Gastroenterol Peru 2007; 27: 177-184.
10. Hojo M, Miwa H, Yokoyama T, Ohkusa T, Nagahara A, Kawabe M, Asaoka D, Izumi Y and Sato N. Treatment of functional dyspepsia with antianxiety or antidepressive agents: systematic review. J Gastroenterol 2005; 40: 1036-1042.
11. Zwolinska-Wcislo M and Galicka-Latala D. [Epidemiology, classification and management of functional dyspepsia]. Przegl Lek 2008; 65: 867-873.
12. Tong JJ, Qi P and HOU XH. The value of Rome III criteria in diagnosis and differentiation of functional dyspepsia. Chin J Dig 2009; 29: 25-28.
13. Tack J, Bisschops R and Sarnelli G. Pathophysiology and treatment of functional dyspepsia. Gastroenterology 2004; 127: 1239-1255.
14. Keohane J and Quigley EM. Functional dyspepsia: the role of visceral hypersensitivity in its pathogenesis. World J Gastroenterol 2006; 12: 2672-2676.
15. Matsumoto Y, Ito M, Kamino D, Tanaka S, Haruma K and Chayama K. Relation between histologic gastritis and gastric motility in Japanese patients with functional dyspepsia: evaluation by transabdominal ultrasonography. J Gastroenterol 2008; 43: 332-337.
16. Shimada M, Ando T, Peek RM, Watanabe O, Ishiguro K, Maeda O, Ishikawa D, Hasegawa M, Ina K, Ohmiya N, Niwa Y and Goto H. Helicobacter pylori infection upregulates interleukin-18 production from gastric epithelial cells. Eur J Gastroenterol Hepatol 2008; 20: 1144-1150.
17. Arruda SM, Forones NM, Juca NT and de Barros KS. Could gastric histology be a useful marker for making decision on Helicobacter pylori eradication therapy in patients with dyspepsia? Arq Gastroenterol 2009; 46: 209-213.
18. Dobrek L, Nowakowski M, Sygula A and Thor PJ. Gastric emptying in patients with gastroesophageal reflux disease and postprandial distress syndrome--preliminary results. Przegl Lek 2009; 66: 413-417.
19. Machado RS, Reber M, Patricio FR and Kawakami E. Gastric emptying of solids is slower in functional dyspepsia unrelated to Helicobacter pylori infection in female children and teenagers. J Pediatr Gastroenterol Nutr 2008; 46: 403-408.
20. Bercik P, Verdu EF, Foster JA, Lu J, Scharringa A, Kean I, Wang L, Blennerhassett P and Collins SM. Role of gut-brain axis in persistent abnormal feeding behavior in mice following eradication of Helicobacter pylori infection. Am J Physiol Regul Integr Comp Physiol 2009; 296: R587-594.