A cisplatin plus pirarubicin-based JPLT2 chemotherapy for hepatoblastoma: Experience and future of the Japanese Study Group for Pediatric Liver Tumor (JPLT)

Pediatric Surgery International

Volumn 29, Issue 10, 2013, Pages 1071-1075

  Hiyama, Eiso ^a,b   Ueda, Yuka ^a   Onitake, Yoshiyuki ^a   Kurihara, Shou ^a   Watanabe, Kenichiro ^b   Hishiki, Tomoro ^b   Tajiri, Tatsuro ^b   Ida, Komei ^b   Yano, Michihiro ^b   Kondo, Satoshi ^b   Oue, Takaharu ^b  

^a HIROSHIMA UNIVERSITY HOSPITAL   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Chemotherapy; CHIC (Childhood Hepatic Tumor International Consortium); Clinical trial; Hepatoblastoma; International collaboration

Indexed keywords

CISPLATIN; PIRARUBICIN;

ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; CHILD; DISTANT METASTASIS; EVENT FREE SURVIVAL; HEPATOBLASTOMA; HIGH RISK PATIENT; HUMAN; LIVER METASTASIS; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; SURVIVAL RATE; SURVIVAL TIME;

ANTINEOPLASTIC AGENTS; CHILD; CISPLATIN; DISEASE-FREE SURVIVAL; DOXORUBICIN; DRUG THERAPY, COMBINATION; FOLLOW-UP STUDIES; HEPATOBLASTOMA; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INCIDENCE; LIVER NEOPLASMS; NEOPLASM RECURRENCE, LOCAL; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84885631058     PISSN: 01790358     EISSN: 14379813     Source Type: Journal    
DOI: 10.1007/s00383-013-3399-0     Document Type: Article

References (19)

1. Lopez-Terrada D, Zimmermann A (2012) Current issues and controversies in the classification of pediatric hepatocellular tumors. Pediatr Blood Cancer 59:780-784
2. Spector LG, Birch J (2012) The epidemiology of hepatoblastoma. Pediatr Blood Cancer 59:776-779
3. Ikeda H, Hachitanda Y, Tanimura M, Maruyama K, Koizumi T, Tsuchida Y (1998) Development of unfavorable hepatoblastoma in children of very low birth weight: results of a surgical and pathologic review. Cancer 82:1789-1796 (Pubitemid 28208932)
4. Perilongo G, Malogolowkin M, Feusner J (2012) Hepatoblastoma clinical research: lessons learned and future challenges. Pediatr Blood Cancer 59:818-821
5. Malogolowkin MH, Katzenstein H, Krailo MD, Chen Z, Bowman L, Reynolds M, Finegold M, Greffe B, Rowland J, Newman K, Womer RB, London WB, Castleberry RP (2006) Intensified platinum therapy is an ineffective strategy for improving outcome in pediatric patients with advanced hepatoblastoma. J Clin Oncol 24:2879-2884 (Pubitemid 46630589)
6. Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G (2012) Children's Oncology Group's 2013 blueprint for research: rare tumors. Pediatr Blood Cancer. doi: 10.1002/pbc.24428
7. Sasaki F, Matsunaga T, Iwafuchi M, Hayashi Y, Ohkawa H, Ohira M, Okamatsu T, Sugito T, Tsuchida Y, Toyosaka A, Nagahara N, Nishihira H, Hata Y, Uchino J, Misugi K, Ohnuma N (2002) Outcome of hepatoblastoma treated with the JPLT-1 (Japanese Study Group for Pediatric Liver Tumor) Protocol-1: a report from the Japanese Study Group for Pediatric Liver Tumor. J Pediatr Surg 37:851-856 (Pubitemid 34575792)
8. Zsiros J, Maibach R, Shafford E, Brugieres L, Brock P, Czauderna P, Roebuck D, Childs M, Zimmermann A, Laithier V, Otte JB, de Camargo B, MacKinlay G, Scopinaro M, Aronson D, Plaschkes J, Perilongo G (2010) Successful treatment of childhood high-risk hepatoblastoma with dose-intensive multiagent chemotherapy and surgery: final results of the SIOPEL-3HR study. J Clin Oncol 28:2584-2590
9. Tajiri T, Kimura O, Fumino S, Furukawa T, Iehara T, Souzaki R, Kinoshita Y, Koga Y, Suminoe A, Hara T, Kohashi K, Oda Y, Hishiki T, Hosoi H, Hiyama E, Taguchi T (2012) Surgical strategies for unresectable hepatoblastomas. J Pediatr Surg 47:2194-2198
10. Malogolowkin MH, Stanley P, Steele DA, Ortega JA (2000) Feasibility and toxicity of chemoembolization for children with liver tumors. J Clin Oncol 18:1279-1284 (Pubitemid 30159846)
11. Xuewu J, Jianhong L, Xianliang H, Zhongxian C (2006) Combined treatment of hepatoblastoma with transcatheter arterial chemoembolization and surgery. Pediatr Hematol Oncol 23:1-9 (Pubitemid 41769967)
12. Meyers RL, Tiao GM, Dunn SP, Langham MR Jr (2012) Liver transplantation in the management of unresectable hepatoblastoma in children. Front Biosci (Elite Ed) 4:1293-1302
13. Hishiki T, Matsunaga T, Sasaki F, Yano M, Ida K, Horie H, Kondo S, Watanabe K, Oue T, Tajiri T, Kamimatsuse A, Ohnuma N, Hiyama E (2011) Outcome of hepatoblastomas treated using the Japanese Study Group for Pediatric Liver Tumor (JPLT) protocol-2: report from the JPLT. Pediatr Surg Int 27:1-8
14. Ueda Y, Hiyama E, Kamimatsuse A, Kamei N, Ogura K, Sueda T (2011) Wnt signaling and telomerase activation of hepatoblastoma: correlation with chemosensitivity and surgical resectability. J Pediatr Surg 46:2221-2227
15. Hiyama E, Yamaoka H, Matsunaga T, Hayashi Y, Ando H, Suita S, Horie H, Kaneko M, Sasaki F, Hashizume K, Nakagawara A, Ohnuma N, Yokoyama T (2004) High expression of telomerase is an independent prognostic indicator of poor outcome in hepatoblastoma. Br J Cancer 91:972-979 (Pubitemid 39273793)
16. Shalaby T, Hiyama E, Grotzer MA (2010) Telomere maintenance as therapeutic target in embryonal tumours. Anticancer Agents Med Chem 10:196-212
17. Arai Y, Honda S, Haruta M, Kasai F, Fujiwara Y, Ohshima J, Sasaki F, Nakagawara A, Horie H, Yamaoka H, Hiyama E, Kaneko Y (2010) Genome-wide analysis of allelic imbalances reveals 4q deletions as a poor prognostic factor and MDM4 amplification at 1q32.1 in hepatoblastoma. Genes Chromosomes Cancer 49:596-609
18. Honda S, Arai Y, Haruta M, Sasaki F, Ohira M, Yamaoka H, Horie H, Nakagawara A, Hiyama E, Todo S, Kaneko Y (2008) Loss of imprinting of IGF2 correlates with hypermethylation of the H19 differentially methylated region in hepatoblastoma. Br J Cancer 99:1891-1899
19. Honda S, Haruta M, Sugawara W, Sasaki F, Ohira M, Matsunaga T, Yamaoka H, Horie H, Ohnuma N, Nakagawara A, Hiyama E, Todo S, Kaneko Y (2008) The methylation status of RASSF1A promoter predicts responsiveness to chemotherapy and eventual cure in hepatoblastoma patients. Int J Cancer 123:1117-1125 Technology Technology