Modulation of CEST images in vivo by T 1 relaxation: A new approach in the design of responsive PARACEST agents

Journal of the American Chemical Society

Volumn 135, Issue 40, 2013, Pages 14904-14907

  Ratnakar, S James ^a   Soesbe, Todd C ^a   Lumata, Lloyd Laporca ^a   Do, Quyen N ^b   Viswanathan, Subha ^a   Lin, Chien Yuan ^a   Sherry, A Dean ^a,b   Kovacs, Zoltan ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FREE RADICALS; MAGNETIC RESONANCE IMAGING; MODULATION; PARAMAGNETISM;

BULK WATER; LONGITUDINAL RELAXATION TIME; NEW APPROACHES; NITROXIDE FREE RADICALS; NITROXIDES; PARACEST; PARAMAGNETIC CHEMICAL-EXCHANGE-SATURATION- TRANSFERS; T1 RELAXATION;

EUROPIUM COMPOUNDS;

1,4,7,10 TETRAAZACYCLODODECANE 1,7 BIS[ACETIC ACID(GLYCEINE TERT BUTYLESTER)AMIDE 4,10 BIS[ACETIC ACID(2',2',6',6 TETRAMETHYL 1' OXYL 4' PIPERIDYL)AMIDE]; ASCORBIC ACID; FREE RADICAL; NITROXIDE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; PROTON; TETRAXETAN; UNCLASSIFIED DRUG; WATER;

ANIMAL TISSUE; ARTICLE; ELECTRON; ELECTRON SPIN RESONANCE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PARAMAGNETIC CHEMICAL EXCHANGE SATURATION TRANSFER; PROTON NUCLEAR MAGNETIC RESONANCE; URINALYSIS;

ANIMALS; CONTRAST MEDIA; DRUG DESIGN; FEMALE; HETEROCYCLIC COMPOUNDS, 1-RING; MAGNETIC PHENOMENA; MAGNETIC RESONANCE IMAGING; MICE; OXIDATION-REDUCTION; PROTONS; TIME FACTORS; WATER;

EID: 84885630508     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja406738y     Document Type: Article

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