Exploring anxiety symptoms in a large-scale twin study of children with autism spectrum disorders, their co-twins and controls

Journal of Child Psychology and Psychiatry and Allied Disciplines

Volumn 54, Issue 11, 2013, Pages 1176-1185

  Hallett, Victoria ^a   Ronald, Angelica ^b   Colvert, Emma ^a   Ames, Catherine ^a   Woodhouse, Emma ^a   Lietz, Stephanie ^a   Garnett, Tracy ^c   Gillan, Nicola ^c   Rijsdijk, Fruhling ^a   Scahill, Lawrence ^d   Bolton, Patrick ^a   Happé, Francesca ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF LONDON   (United Kingdom)

^c SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST   (United Kingdom)

^d YALE UNIVERSITY   (United States)

Author keywords

anxiety; Autism spectrum disorders; comorbidity; siblings; twin

Indexed keywords

ADOLESCENT; ANXIETY; ARTICLE; AUTISM; CHILD; COMORBIDITY; COMPARATIVE STUDY; FEMALE; HUMAN; LONGITUDINAL STUDY; MALE; PSYCHOLOGICAL ASPECT; PSYCHOLOGICAL RATING SCALE; STATISTICS; TWINS; UNITED KINGDOM;

ADOLESCENT; ANXIETY; CHILD; CHILD DEVELOPMENT DISORDERS, PERVASIVE; COMORBIDITY; DISEASES IN TWINS; FEMALE; GREAT BRITAIN; HUMANS; LONGITUDINAL STUDIES; MALE; PSYCHIATRIC STATUS RATING SCALES; TWINS;

EID: 84885624137     PISSN: 00219630     EISSN: 14697610     Source Type: Journal    
DOI: 10.1111/jcpp.12068     Document Type: Article

References (42)

1. Autism Genetic Resource Exchange. Available from: http://research.agre. org/agrecatalog/algorithm.cfm [last accessed 12 November 2012].
2. Bolton, P.F., Pickles, A., Murphy, M., &, Rutter, M., (1998). Autism, affective and other psychiatric disorders: Patterns of familial aggregation. Psychological Medicine, 28, 385-395.
3. Chorpita, B.F., Moffitt, C.E., &, Gray, J., (2005). Psychometric properties of the Revised Child Anxiety and Depression Scale in a clinical sample. Behaviour Research and Therapy, 43, 309-322.
4. Chorpita, B.F., Yim, L., Moffitt, C., Umemoto, L.A., &, Francis, S.E., (2000). Assessment of symptoms of DSM-IV anxiety and depression in children: A revised child anxiety and depression scale. Behaviour Research and Therapy, 38, 835-855.
5. Costello, E. J., Egger, H.L., &, Angold, A., (2005). The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity. Child and adolescent psychiatric clinics of North America, 14, 631-648. vii.
6. Dunn, L.M., (1997). The British picture vocabulary scale (2nd edn). Windsor: NFER-Nelson.
7. Farrugia, S., &, Hudson, J., (2006). nxiety in adolescents with Asperger syndrome: Negative thoughts, behavioral problems, and life interference. Focus on Autism and Other Developmental Disabilities, 21, 35.
8. Gadow, K. D., Devincent, C.J., Pomeroy, J., &, Azizian, A., (2005). Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism: The International Journal of Research and Practice, 9, 392-415.
9. Gillott, A., Furniss, F., &, Walter, A., (2001). Anxiety in high-functioning children with autism. Autism: The International Journal of Research and Practice, 5, 277-286.
10. Goodman, R., Ford, T., Richards, H., Gatward, R., &, Meltzer, H., (2000). The Development and Well-Being Assessment: Description and initial validation of an integrated assessment of child and adolescent psychopathology. Journal of Child Psychology and Psychiatry, 41, 645-655.
11. Gotham, K., Risi, S., Pickles, A., &, Lord, C., (2007). The Autism Diagnostic Observation Schedule: Revised algorithms for improved diagnostic validity. Journal of Autism and Developmental Disorders, 37, 613-627.
12. Gregory, A.M., &, Eley, T.C., (2007). Genetic influences on anxiety in children: What we've learned and where we're heading. Clinical Child and Family Psychology Review, 10, 199-212.
13. Hallett, V., Ronald, A., Rijsdijk, F., &, Happe, F., (2010). Association of autistic-like and internalizing traits during childhood: A longitudinal twin study. The American Journal of Psychiatry, 167, 809-817.
14. Howlin, P., Mawhood, L., &, Rutter, M., (2000). Autism and developmental receptive language disorder-A follow-up comparison in early adult life. II: Social, behavioural, and psychiatric outcomes. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 41, 561-578.
15. Jacob, S., Landeros-Weisenberger, A., &, Leckman, J.F., (2009). Autism spectrum and obsessive-compulsive disorders: OC behaviors, phenotypes and genetics. Autism Research: Official Journal of the International Society for Autism Research, 2, 293-311.
16. Kanner, L., (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217-250.
17. Le Couteur, A., Lord, C., &, Rutter, M., (2003). Autism diagnostic interview-revised. Los Angeles: Western Psychological Services.
18. Lecavalier, L., (2006). Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subject characteristics, and empirical classification. Journal of Autism and Developmental Disorders, 36, 1101-1114.
19. Lecavalier, L., Aman, M.G., Scahill, L., McDougle, C.J., McCracken, J.T., Vitiello, B.,. &, Kau, A.S., (2006). Validity of the autism diagnostic interview-revised. American Journal of Mental Retardation: AJMR, 111, 199-215.
20. Leyfer, O.T., Folstein, S.E., Bacalman, S., Davis, N.O., Dinh, E., Morgan, J.,. &, Lainhart, J.E., (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849-861.
21. Mazefsky, C.A., Folstein, S.E., &, Lainhart, J.E., (2008). Overrepresentation of mood and anxiety disorders in adults with autism and their first-degree relatives: What does it mean? Autism Research: Official Journal of the International Society for Autism Research, 1, 193-197.
22. Muris, P., Steerneman, P., Merckelbach, H., Holdrinet, I., &, Meesters, C., (1998). Comorbid anxiety symptoms in children with pervasive developmental disorders. Journal of Anxiety Disorders, 12, 387-393.
23. Neale, M., Boker, S., Xie, G., &, Maes, H., (2003). MX: Statistical modeling (6th edn). Richmond: Department of Psychiatry, Medical College of Virginia.
24. Oliver, B.R., &, Plomin, R., (2007). Twins' Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behavior problems from childhood through adolescence. Twin Research and Human Genetics, 10, 96-105.
25. Pickles, A., Starr, E., Kazak, S., Bolton, P., Papanikolaou, K., Bailey, A.,. &, Rutter, M., (2000). Variable expression of the autism broader phenotype: Findings from extended pedigrees. Journal of Child Psychology and Psychiatry and Allied Disciplines, 41, 491-502.
26. Piven, J., Chase, G.A., Landa, R., Wzorek, M., Gayle, J., Cloud, D., &, Folstein, S., (1991). Psychiatric disorders in the parents of autistic individuals. Journal of the American Academy of Child and Adolescent Psychiatry, 30, 471-478.
27. Piven, J., Gayle, J., Chase, G.A., Fink, B., Landa, R., Wzorek, M.M., &, Folstein, S.E., (1990). A family history study of neuropsychiatric disorders in the adult siblings of autistic individuals. Journal of the American Academy of Child and Adolescent Psychiatry, 29, 177-183.
28. Piven, J., &, Palmer, P., (1999). Psychiatric disorder and the broad autism phenotype: Evidence from a family study of multiple-incidence autism families. American Journal of Psychiatry, 156, 557-563.
29. Raven, J.C., (1958). Raven's standard progressive matrices. London: H.K. Lewis & Co. Ltd.
30. Russell, E., &, Sofronoff, K., (2005). Anxiety and social worries in children with Asperger syndrome. Australian and New Zealand Journal of Psychiatry, 39, 633-638.
31. Scott, F.J., Baron-Cohen, S., Bolton, P., &, Brayne, C., (2002). The CAST (Childhood Asperger Syndrome Test): Preliminary development of a UK screen for mainstream primary-school-age children. Autism, 6, 9-31.
32. Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., &, Baird, G., (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921-929.
33. Smalley, S.L., McCracken, J., &, Tanguay, P., (1995). Autism, affective disorders, and social phobia. American Journal of Medical Genetics, 60, 19-26.
34. van Steensel, F. J., Bogels, S. M., &, Perrin, S., (2011). Anxiety disorders in children and adolescents with autistic spectrum disorders: A meta-analysis. Clinical Child and Family Psychology Review, 14, 302-317.
35. Sukhodolsky, D.G., Scahill, L., Gadow, K.D., Arnold, L.E., Aman, M.G., McDougle, C.J.,. &, Vitiello, B., (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36, 117-128.
36. Trouton, A., Spinath, F.M., &, Plomin, R., (2002). Twins early development study (TEDS): A multivariate, longitudinal genetic investigation of language, cognition and behavior problems in childhood. Twin Research, 5, 444-448.
37. Wechsler, D., (1999). Wechsler Abbreviated Scale of Intelligence. The Psychological Corporation. New York: Harcourt Brace & Company.
38. Weisbrot, D.M., Gadow, K.D., DeVincent, C.J., &, Pomeroy, J., (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 15, 477-496.
39. White, S.W., Oswald, D., Ollendick, T., &, Scahill, L., (2009). Anxiety in children and adolescents with autism spectrum disorders. Clinical Psychology Review, 29, 216-229.
40. Willemsen-Swinkels, S.H.N., Buitelaar, J.K., Dekker, M., &, van Engeland, H., (1998). Subtyping stereotypic behavior in children: The association between stereotypic behavior, mood, and heart rate. Journal of Autism and Developmental Disorders, 28, 547-557.
41. Williams, J., Allison, C., Scott, F., Stott, C., Bolton, P., Baron-Cohen, S., &, Brayne, C., (2006). The Childhood Asperger Syndrome Test (CAST)-Test-retest reliability. Autism: The International Journal of Research and Practice, 10, 415-427.
42. Wren, F.J., Bridge, J.A., &, Birmaher, B., (2004). Screening for childhood anxiety symptoms in primary care: Integrating child and parent reports. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1364-1371.