Severity illness scoring systems for early identification and prediction of in-hospital mortality in patients with suspected sepsis presenting to the emergency department

Wiener Klinische Wochenschrift

Volumn 125, Issue 17-18, 2013, Pages 508-515

  Geier, Felicitas ^a,b   Popp, Steffen ^a   Greve, Yvonne ^a   Achterberg, Andreas ^a   Glöckner, Erika ^a   Ziegler, Renate ^a   Heppner, Hans Jürgen ^a,b   Mang, Harald ^b   Christ, Michael ^a  

^a Nuremberg Hospital   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

early identification; emergency department; prognosis; sepsis; severityillness scoring systems

Indexed keywords

ABDOMINAL INFECTION; ADULT; AGED; ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE SEVERITY; EMERGENCY SEVERITY INDEX; EMERGENCY WARD; FEMALE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MODIFIED EARLY WARNING SCORE; MORTALITY; MORTALITY IN EMERGENCY DEPARTMENT SEPSIS SCORE; OBSERVATIONAL STUDY; PNEUMONIA; PREDICTIVE VALUE; PROGNOSIS; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SEPSIS; SEPTIC SHOCK; URINARY TRACT INFECTION;

AGED; CRITICAL ILLNESS; EMERGENCY SERVICE, HOSPITAL; FEMALE; GERMANY; HOSPITAL MORTALITY; HUMANS; INCIDENCE; MALE; MIDDLE AGED; PROGNOSIS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SEPSIS; SEVERITY OF ILLNESS INDEX; SURVIVAL ANALYSIS;

EID: 84885598185     PISSN: 00435325     EISSN: 16137671     Source Type: Journal    
DOI: 10.1007/s00508-013-0407-2     Document Type: Article

References (21)

1. Hagel S, Brunkhorst F. Sepsis. Intensivmed. 2011;48:57-73.
2. Engel C, Brunkhorst FM, Bone HG, et al. Epidemiology of sepsis in Germany: results from a national prospective multicenter study. Intensive Care Med. 2007;33:606-18.
3. Bundesministerium für Bildung und Forschung. Gesundheitsforschung: Forschung für den Menschen. In: Newsletter No. 17. 2004. http://www.gesundheitsforschung-bmbf.de/-media/NL-17.pdf. Accessed 29 Jan 2013.
4. Martin GS, Mannino DM, Eaton S, et al. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003;348:1546-54.
5. Center for Sepsis Control and Care. Was ist Sepsis? 2012. http://www.cscc.uniklinikum-jena.de/Sepsis.html. Accessed 13 Jan 2013.
6. Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34:1589-96.
7. Christ M, Grossmann F, Winter D, et al. Triage in der Notaufnahme. Moderne, evidenzbasierte Ersteinschätzung der Behandlungsdringlichkeit. Dtsch Arztebl. 2010;107:892-8.
8. National Institute for Health and Clinical Excellence. Acutely ill patients in hospital. Recognition of and response to acute illness in adults in hospital. 2007. http://www.nice.org.uk/nicemedia/pdf/CG50FullGuidance.pdf. Accessed 13 Jan 2013.
9. Shelton R. The emergency severity index 5-level triage system. Dimens Crit Care Nurs. 2009;28:9-12.
10. Subbe CP, Kruger M, Rutherford P, et al. Validation of a modified early warning score in medical admissions. Q J Med. 2001;94:521-6.
11. Shapiro NI, Howell MD, Talmor D, et al. Mortality in emergency department sepsis (MEDS) score predicts 1-year mortality. Crit Care Med. 2007;35:192-8.
12. Grafstein E, Bullard MJ, Warren D, et al. Revision of the Canadian Emergency Department Information System (CEDIS) presenting compaint list version 1.1. CJEM. 2008;10:151-61.
13. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies. Developement and validation. J Chronic Dis. 1987;40:373-83.
14. Dellinger RP, Levy MM, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock. 2012. http://www.survivingsepsis.org/News/Pages/2012-Sepsis-Guidelines-Published. aspx. Accessed 5 Feb 2013.
15. Deutsches Institut für Medizinische Dokumentation und Information. Alpha-ID. Identifikationsnummer für Diagnosen. 2012. http://www.dimdi.de/ static/de/klassi/alpha-id/index.htm. Accessed 31 Jan 2013.
16. Ghanem-Zoubi NO, Vardi M, Laor A, et al. Assessment of disease-severity scoring systems for patients with sepsis in general internal medicine departments. Crit Care. 2011;15:1-7.
17. Sankoff JD, Goyal M, Gaieski DF, et al. Validation of the mortality in emergency department sepsis (MEDS) score in patients with the systemic inflammatory response syndrome (SIRS). Crit Care Med. 2008;36:421-6.
18. Howell MD, Donnino MW, Talmor D, et al. Performance of severity of illness scoring systems in emergency department patients with infection. Acad Emerg Med. 2007;14:709-14.
19. Shapiro NI, Wolfe RE, Moore RB, et al. Mortality in emergency department sepsis (MEDS) score: a prospectively derived and validated clinical prediction rule. Crit Care Med. 2003;31:670-5.
20. Garrouste-Orgeas M, Boumendil A, Pateron D, et al. Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria. An observational, multicenter, prospective study. Crit Care Med. 2009;37:2919-28.
21. Esteban A, Frutos-Vivar F, Ferguson ND, et al. Sepsis incidence and outcome. Contrasting the intensive care unit with the hospital ward. Crit Care Med. 2007;35:1284-9.