Live imaging of individual cell divisions in mouse neuroepithelium shows asymmetry in cilium formation and Sonic hedgehog response

Cilia

Volumn 1, Issue , 2012, Pages

  Piotrowska Nitsche, Karolina ^a,b   Caspary, Tamara ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b POLISH ACADEMY OF SCIENCES   (Poland)

Author keywords

Cell division; Ex vivo live imaging; Imaging neuroepithelium; Primary cilia; Shh

Indexed keywords

SONIC HEDGEHOG PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CONTROLLED STUDY; DAUGHTER CELL; EMBRYO; EUKARYOTIC FLAGELLUM; FLUORESCENCE IMAGING; MOUSE; MOUSE EMBRYO; NERVOUS SYSTEM DEVELOPMENT; NEURAL TUBE; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ERINACEIDAE;

EID: 84885595469     PISSN: None     EISSN: 20462530     Source Type: Journal    
DOI: 10.1186/2046-2530-1-6     Document Type: Article

References (23)

1. Liu A, Rakeman AS, Murcia NS, Niswander L, Anderson K. Hedgehog signalling in the mouse requires intraflagellar transport proteins. Nature 2003, 426(6962):83-87. 10.1038/nature02061, 14603322.
2. Davis EE, Brueckner M, Katsanis N. The emerging complexity of the vertebrate cilium: new functional roles for an ancient organelle. Dev Cell 2006, 11(1):9-19. 10.1016/j.devcel.2006.06.009, 16824949.
3. Goetz SC, Anderson KV. The primary cilium: a signaling centre during vertebrate development. Nat Rev Genet 2010, 11(5):331-344. 10.1038/nrg2774, 3121168, 20395968.
4. Fliegauf M, Benzing T, Omran H. When cilia go bad: cilia defects and ciliopathies. Nat Rev Mol Cell Biol 2007, 8:880-893. 10.1038/nrm2278, 17955020.
5. Singla V, Reiter JF. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science 2006, 313(5787):629-633. 10.1126/science.1124534, 16888132.
6. Gerdes JM, Davis EE, Katsanis N. The vertebrate primary cilium in development, homeostasis, and disease. Cell 2009, 137(1):32-45. 10.1016/j.cell.2009.03.023, 3016012, 19345185.
7. Tucker RW, Pardee AB, Fujiwara K. Centriole ciliation is related to quiescence and DNA synthesis in 3T3 cells. Cell 1979, 17(3):527-535. 10.1016/0092-8674(79)90261-7, 476831.
8. Anderson CT, Stearns T. Centriole age underlies asynchronous primary cilium growth in mammalian cells. Curr Biol 2009, 19(17):1498-1502. 10.1016/j.cub.2009.07.034, 3312602, 19682908.
9. Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP. Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 1993, 75:1417-1430. 10.1016/0092-8674(93)90627-3, 7916661.
10. Ericson J, Muhr J, Placzek M, Lints T, Jessell TM, Edlund T. Sonic hedgehog induces the differentiation of ventral forebrain neurons: A common signal for ventral patterning within the neural tube. Cell 1995, 81:747-756. 10.1016/0092-8674(95)90536-7, 7774016.
11. Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 1996, 383:407-413. 10.1038/383407a0, 8837770.
12. Jones EAV, Crotty D, Kulesa PM, Waters CW, Baron MH, Fraser SE, Dickinson ME. Dynamic in vivo imaging of postimplantation mammalian embryos using whole embryo culture. Genesis 2002, 34:228-235. 10.1002/gene.10162, 12434332.
13. Vintersten K, Monetti C, Gertsenstein M, Zhang P, Laszlo L, Biechele S, Nagy A. Mouse in red: red fluorescent protein expression in mouse ES cells, embryos, and adult animals. Genesis 2004, 40(4):241-246. 10.1002/gene.20095, 15593332.
14. Hayashi S, McMahon AP. Efficient recombination in diverse tissue by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol 2002, 244(2):305-318. 10.1006/dbio.2002.0597, 11944939.
15. Yamada T, Pfaff SL, Edlund T, Jessell TM. Control of cell pattern in the neural tube: motor neuron induction by diffusible factors from notochord and floor plate. Cell 1993, 73:673-686. 10.1016/0092-8674(93)90248-O, 8500163.
16. Caspary T, Larkins CE, Anderson KV. The graded response to Sonic Hedgehog depends on cilia architecture. Dev Cell 2007, 12(5):767-778. 10.1016/j.devcel.2007.03.004, 17488627.
17. Berbari NF, Johnson AD, Lewis JS, Askwith CC, Mykytyn K. Identification of ciliary localization sequences within the third intracellular loop of G protein-coupled receptors. Mol Biol Cell 2008, 19(4):1540-1547. 10.1091/mbc.E07-09-0942, 2291422, 18256283.
18. Lu QR, Yuk D, Alberta JA, Zhu Z, Pawlitzky I, Chan J, McMahon AP, Stiles CD, Rowitch DH. Sonic hedgehog-regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron 2000, 25(2):317-329. 10.1016/S0896-6273(00)80897-1, 10719888.
19. Lu QR, Sun T, Zhu Z, Ma N, Garcia M, Stiles CD, Rowitch DH. Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection. Cell 2002, 109(1):75-86. 10.1016/S0092-8674(02)00678-5, 11955448.
20. Zhou Q, Anderson DJ. The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell 2002, 109(1):61-73. 10.1016/S0092-8674(02)00677-3, 11955447.
21. Mukouyama YS, Deneen B, Lukaszewicz A, Novitch BG, Wichterle H, Jessell TM, Anderson DJ. Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proc Natl Acad Sci USA 2006, 103(5):1551-1556. 10.1073/pnas.0510658103, 1345718, 16432183.
22. Corbit KC, Aanstad P, Singla V, Norman AR, Stainier DY, Reiter JF. Vertebrate smoothened functions at the primary cilium. Nature 2006, 437(7061):1018-1021.
23. Rohatgi R, Milenkovic L, Scott MP. Patched1 regulates hedgehog signaling at the primary cilium. Science 2007, 317:372-376. 10.1126/science.1139740, 17641202.