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Volumn 27, Issue 10, 2013, Pages 2075-2077

Reduced CXCR4 expression is associated with extramedullary disease in a mouse model of myeloma and predicts poor survival in multiple myeloma patients treated with bortezomib

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CHEMOKINE RECEPTOR CXCR4; CISPLATIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; MESSENGER RNA; THALIDOMIDE;

EID: 84885595409     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2013.148     Document Type: Letter
Times cited : (44)

References (14)
  • 2
    • 70450227260 scopus 로고    scopus 로고
    • Proteasome inhibitors in the treatment of multiple myeloma
    • Shah JJ, Orlowski RZ. Proteasome inhibitors in the treatment of multiple myeloma. Leukemia 2009; 23: 1964-1979.
    • (2009) Leukemia , vol.23 , pp. 1964-1979
    • Shah, J.J.1    Orlowski, R.Z.2
  • 3
    • 84879293601 scopus 로고    scopus 로고
    • Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model
    • e-pub ahead of print 27 March, doi:10.1158/1535-7163.MCT-12-1151
    • Stessman HA, Baughn LB, Sarver A, Xia T, Deshpande R, Mansoor A et al. Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model. Mol Cancer Ther 2013, e-pub ahead of print 27 March 2013; doi:10.1158/1535-7163.MCT-12-1151.
    • (2013) Mol Cancer Ther 2013
    • Stessman, H.A.1    Baughn, L.B.2    Sarver, A.3    Xia, T.4    Deshpande, R.5    Mansoor, A.6
  • 4
    • 3042806890 scopus 로고    scopus 로고
    • Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice
    • Cheung WC, Kim JS, Linden M, Peng L, Van Ness B, Polakiewicz RD et al. Novel targeted deregulation of c-Myc cooperates with Bcl-X(L) to cause plasma cell neoplasms in mice. J Clin Invest 2004; 113: 1763-1773.
    • (2004) J Clin Invest , vol.113 , pp. 1763-1773
    • Cheung, W.C.1    Kim, J.S.2    Linden, M.3    Peng, L.4    Van Ness, B.5    Polakiewicz, R.D.6
  • 5
    • 34249311959 scopus 로고    scopus 로고
    • A transgenic mouse model of plasma cell malignancy shows phenotypic, cytogenetic, and gene expression heterogeneity similar to human multiple myeloma
    • Boylan KL, Gosse MA, Staggs SE, Janz S, Grindle S, Kansas GS et al. A transgenic mouse model of plasma cell malignancy shows phenotypic, cytogenetic, and gene expression heterogeneity similar to human multiple myeloma. Cancer Res 2007; 67: 4069-4078.
    • (2007) Cancer Res , vol.67 , pp. 4069-4078
    • Boylan, K.L.1    Gosse, M.A.2    Staggs, S.E.3    Janz, S.4    Grindle, S.5    Kansas, G.S.6
  • 6
    • 33947600329 scopus 로고    scopus 로고
    • Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma
    • Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM et al. Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood 2007; 109: 2708-2717.
    • (2007) Blood , vol.109 , pp. 2708-2717
    • Alsayed, Y.1    Ngo, H.2    Runnels, J.3    Leleu, X.4    Singha, U.K.5    Pitsillides, C.M.6
  • 7
    • 34147129816 scopus 로고    scopus 로고
    • Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
    • Mulligan G, Mitsiades C, Bryant B, Zhan F, Chng WJ, Roels S et al. Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib. Blood 2007; 109: 3177-3188.
    • (2007) Blood , vol.109 , pp. 3177-3188
    • Mulligan, G.1    Mitsiades, C.2    Bryant, B.3    Zhan, F.4    Chng, W.J.5    Roels, S.6
  • 8
    • 80053356808 scopus 로고    scopus 로고
    • Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with total therapy 3
    • Shaughnessy Jr. JD, Qu P, Usmani S, Heuck CJ, Zhang Q, Zhou Y et al. Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with total therapy 3. Blood 2011; 118: 3512-3524.
    • (2011) Blood , vol.118 , pp. 3512-3524
    • Shaughnessy Jr., J.D.1    Qu, P.2    Usmani, S.3    Heuck, C.J.4    Zhang, Q.5    Zhou, Y.6
  • 9
    • 84873566331 scopus 로고    scopus 로고
    • Improvement in long-term outcomes with successive Total Therapy trials for multiple myeloma: Are patients now being cured
    • Usmani SZ, Crowley J, Hoering A, Mitchell A, Waheed S, Nair B et al. Improvement in long-term outcomes with successive Total Therapy trials for multiple myeloma: are patients now being cured? Leukemia 2013; 27: 226-232.
    • (2013) Leukemia , vol.27 , pp. 226-232
    • Usmani, S.Z.1    Crowley, J.2    Hoering, A.3    Mitchell, A.4    Waheed, S.5    Nair, B.6
  • 11
    • 66149150580 scopus 로고    scopus 로고
    • CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
    • Azab AK, Runnels JM, Pitsillides C, Moreau AS, Azab F, Leleu X et al. CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood 2009; 113: 4341-4351.
    • (2009) Blood , vol.113 , pp. 4341-4351
    • Azab, A.K.1    Runnels, J.M.2    Pitsillides, C.3    Moreau, A.S.4    Azab, F.5    Leleu, X.6
  • 14
    • 84858796584 scopus 로고    scopus 로고
    • Factors influencing the abundance of the side population in a human myeloma cell line
    • Mo SL, Li J, Loh YS, Brown RD, Smith AL, Chen Y et al. Factors influencing the abundance of the side population in a human myeloma cell line. Bone Marrow Res 2011; 2011: 524845.
    • (2011) Bone Marrow Res , vol.2011 , pp. 524-845
    • Mo, S.L.1    Li, J.2    Loh, Y.S.3    Brown, R.D.4    Smith, A.L.5    Chen, Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.