Swarna Bhasma and gold compounds: An innovation of pharmaceutics for illumination of therapeutics

International Journal of Research in Ayurveda and Pharmacy

Volumn 3, Issue 1, 2012, Pages 5-9

  Singh, Neetu ^a   Anand, Chaudhary ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Gold; Immunomodulator; Marana; Rheumatoid arthritis; Swarna bhasma

Indexed keywords

ANALGESIC AGENT; ANTIDEPRESSANT AGENT; ANTIOXIDANT; ANXIOLYTIC AGENT; AURANOFIN; AYURVEDIC DRUG; COLLOIDAL GOLD; DIAGNOSTIC AGENT; GOLD; GOLD CHLORIDE; GOLD DERIVATIVE; GOLD NANOPARTICLE; GOLD NANOPARTICLE EPIDERMAL GROWTH FACTOR RECEPTOR ANTIBODY CONJUGATE; GOLD SALT; IMMUNOMODULATING AGENT; NANOCONJUGATE; SUBSTANCE P; SWARNA BHASMA; THIOMALATE SODIUM; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANTIANGIOGENIC ACTIVITY; ANTIDEPRESSANT ACTIVITY; ANTIOXIDANT ACTIVITY; ANXIETY; AYURVEDA; BEHAVIOR DISORDER; BRAIN DISEASE; BRAIN ISCHEMIA; CANCER DIAGNOSIS; CATALEPSY; CELL MEMBRANE PERMEABILITY; CHRONIC LYMPHATIC LEUKEMIA; DELIRIUM; DEPRESSION; DRUG EFFICACY; DRUG INDICATION; DRUG SAFETY; DRUG STRUCTURE; DRUG SYNTHESIS; GAMETOGENESIS; HUMAN; IMMUNOMODULATION; IMMUNOPATHOLOGY; INSOMNIA; NEUROPATHY; NONHUMAN; PAIN; PARTICLE SIZE; PERIPHERAL NEUROPATHY; REPRODUCTION; REVIEW; RHEUMATOID ARTHRITIS; SIDE EFFECT; STEROIDOGENESIS; TRANQUILIZING ACTIVITY;

EID: 84885584998     PISSN: 22774343     EISSN: 22293566     Source Type: Journal    
DOI: None     Document Type: Review

References (39)

1. Vagbhatta Rasa, Rasa Ratna Samucchya,, Volume I, Commented by D. A. Kulkarni, Meharchand Lacchmandas Publications, New Delhi, 1998; Ch. 5/139, Ch. 5/1, Ch. 5/1-21.
2. Vagbhatta Rasa, Rasa Ratna Samucchya,, Volume I, Commented by D. A. Kulkarni, Meharchand Lacchmandas Publications, New Delhi, 1998; Ch. 5/139, Ch. 5/1, Ch. 5/1-21.
3. th Edition, 1979; Ch. 15/70, Ch. 15/11-116
4. Mehadihassan S. Cinnebar-gold as the best alchemical drug of longevity, called Makardhwaja in India. Am. J. Chinese medicine, 1985; 13: 93-108.
5. Vagbhatta Rasa, Rasa Ratna Samucchya,, Volume I, Commented by D. A. Kulkarni, Meharchand Lacchmandas Publications, New Delhi, 1998; Ch. 5/139, Ch. 5/1, Ch. 5/1-21.
6. th Edition, 1979; Ch. 15/70, Ch. 15/11-116
7. The Ayurvedic Formulary of India, Part I, GOI, Ministry of Health and Family Welfare, Dept. of ISM&H, Second revised English edition,2003; Page No.246.
8. Christopher L. Brown, Nanogold Phrmaceutics (i) The use of gold to treat experimentally induced arthritis in rat models, (ii) Characterization of the gold in Swarna bhasma, a microparticulate used in traditional Indian medicine, Gold Bulletin, 2007; 40/3.
9. Christopher L. Brown, Nanogold Phrmaceutics (i) The use of gold to treat experimentally induced arthritis in rat models, (ii) Characterization of the gold in Swarna bhasma, a microparticulate used in traditional Indian medicine, Gold Bulletin, 2007; 40/3.
10. A Mitra, S Chakraborty, B Auddy, P Tripathi, S Sen, A.V Saha, B Mukherjee. Evaluation of chemical constituents and free-radical scavenging activity of Swarnabhasma (gold ash), an Ayurvedic drug, Journal of Ethnopharmacology, 2002; 80: 147-/153.
11. Bajaj S, Vohra SB. Anti cataleptic, anti-anxiety and anti-depressant activity of gold preparations used in Indian system of medicine, Indian Journal of Pharmacology, 2000; 32:339-346.
12. Bajaj S, Vohra SB. Analgesic activity of gold preparation used in Ayurveda and Unani- Tibb., Indian Journal of Medical Research, 1998; 108: 104.
13. Shah ZA and Vohra SB. Antioxidant/restorative effects of calcined gold preparations used in Indian systems of medicine against global and focal models of ischemia, Pharmacol. Toxicol, 2002; 90:254.
14. Bajaj S, Ahmad I, Raisuddin S, Vohora SB. Augmentation of nonspecific immunity in mice by gold preparations used in traditional systems of medicine, Indian Journal of Medical Research, 2001; 113: 192.
15. Sharma DC, Jha J, Sharma P, Gaur BL. Evaluation of safety and efficacy of a gold containing Ayurvedic drug, Indian-J-Exp-Biol. 2001 Sep; 39(9): 892-6.
16. Richards DG, Mc Millin DL, Mein EA, Nelson CD. Gold and its relationship to neurological/glandular conditions Intern. J. Neuroscience, 2002; 112: 31-53.
17. Penneys Neal S. et al. Inhibition of prostaglandin synthesis and human epidermal enzymes by aurothiomalate in vitro: possible actions of gold in pemphigus, Journal of Investigative Dermatology, 1974; 63: 356-361.
18. Mukherjee Priyabrata, Potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis, Journal of Nanobiotechnology 2007; 5:4
19. Chattopadhyay A, Sarkar M, Biswas NM. Effect of gold on stimulation of reproductive function in immature female albino rats, Indian Journal of Experimental Biology, December 2006; 44:971-975.
20. Biswas NM, Chattopadhyay A, Sarkar M. Effects of gold on testicular steroidogenic and gametogenic functions in immature male albino rats, Life Sci. 2004; 76(6): 629-36. http://www.ncbi.nlm.nih.gov/pubmed/15567188 accessed on 30.12.10
21. Miguel E De, Arnalich F, Tato E, Vázquez JJ, J Gijón-Baños, Hernanz A. The effect of gold salts on substance P in the rheumatoid arthritis, Neuroscience letters. 1994; 174(2): 185.
22. Christopher L Brown, Nanogold Phrmaceutics (i) The use of gold to treat experimentally induced arthritis in rat models, (ii) Characterization of the gold in Swarna bhasma, a microparticulate used in traditional Indian medicine, Gold Bulletin, 2007; 40/3
23. Mukherjee P, Bhattacharya R, Wang P, Wang L, Basu S, Nagy J A et al. Antiangiogenic properties of gold nanoparticles. Clin Cancer Res.2005;11:3530-4.
24. Harth M., Journal of Rheumatology 1979;Suppl. 7: 11. www.ncbi.nlm.nih.gov/pubmed/385876 cited on 2.12.2010.
25. Measel JW. Effect of gold on the immune response of mice, Infection and immunity, 1975; February 11 (2): 350-354.
26. Niemeyer CM. Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science, Angew Chemie Intern. Ed. Engl., 40: 4128-4158).
27. Ivan H. El-Sayed, Xiaohua Huang and Mostafa A. El-Sayed, Surface Plasmon Resonance Scattering and Absorption of anti-EGFR Antibody Conjugated Gold Nanoparticles in Cancer Diagnostics: Applications in Oral Cancer, Nano Lett., 2005;5 (5): 829-834, http://pubs.acs.org/doi/abs/10.1021/nl050074e cited on 29.12.2010
28. Richards DG, Mc Millin DL., Mein EA, Nelson CD. Gold and its relationship to neurological/glandular conditions Intern. J. Neuroscience, 2002; 112: 31-53.
29. CL Brown, G Bushell, MW Whitehouse, DS Agrawal, SG Tupe, KM Paknikar and ERT Tiekink, Gold 2006 presentation nanogoldpharmaceutics. Gold Bull. 2007;40:245-250.
30. Wadekkar MCS. Division of Biochemical Sciences, National Chemical Laboratory, Pune, India, lecture delivered at Post Graduate Chemistry Department, Bharati Vidyapeeth Deemed University, Pune, India.
31. Shastri Murali, Power point Presentation, New Methods for the synthesis of Nano materials,69 annual meeting of the Indian Academy of Science, Guwahati,2003
32. Haruta M. Size-and support dependency in the catalysis of gold. Catal. Today, 1997; 36:153-166.
33. Sanchez A et al. When gold is not noble: nanoscale gold catalysts. J.Phys. Chem.A, 1999; 103:9573-9578.
34. Hughes MD, Hughes MD, Xu YJ, Jenkins P, Mc Morn P, Landon P, Enache D I, Tunable gold catalysts for selective hydrocarbon oxidation under mild conditions. Nature 2005; 437:1132-1135.
35. Tsunoyama H, Sakurai H, Negishi Y & Tsukuda T. Size-specific catalytic activity of polymer-stabilized gold nanoclusters for aerobic alcohol oxidation in water. J. Am. Chem. Soc., 2005; 127: 9374 - 9375.
36. Chen MS & Goodman DW. Structure-activity relationships in supported Au catalysts. Catal. Today, 2006; 111:22-33.
37. Li ZY, Young NP, Vece MDi, Palomba S, Palmer RE, Blelochet AL. Three-dimensional atomic-scale structure of size-selected gold nanoclusters, Nature. 2008; 451
38. th Feb 2006
39. Raviraja N Seetharam et al., Nanotoxicity: Threat posed by nanoparticles, Current Science, 2007; 93(6):25