Reductions in genetic diversity of Schistosoma mansoni populations under chemotherapeutic pressure: The effect of sampling approach and parasite population definition

Acta Tropica

Volumn 128, Issue 2, 2013, Pages 196-205

  French, Michael D ^a   Churcher, Thomas S ^a   Basáñez, María Gloria ^a   Norton, Alice J ^a,c   Lwambo, Nicholas J S ^b   Webster, Joanne P ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (Tanzania)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Monitoring and evaluation; Population genetics; Praziquantel; Preventive chemotherapy; Sampling protocol; Schistosoma mansoni; Stochastic re sampling; Tanzania

Indexed keywords

PRAZIQUANTEL;

CHEMOTHERAPY; DRUG; FLATWORM; GENETIC VARIATION; POPULATION GENETICS; SAMPLING; SCHISTOSOMIASIS;

ARTICLE; CHILD; GENETIC VARIABILITY; HETEROZYGOSITY; HOST; HUMAN; MAJOR CLINICAL STUDY; MIRACIDIUM; NONHUMAN; PARASITE TRANSMISSION; POPULATION STRUCTURE; PRESCHOOL CHILD; RELIABILITY; SAMPLING; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SCHOOL CHILD; TANZANIA; TREMATODE LIFE CYCLE STAGE;

TANZANIA;

SCHISTOSOMA; SCHISTOSOMA MANSONI;

MONITORING AND EVALUATION; POPULATION GENETICS; PRAZIQUANTEL; PREVENTIVE CHEMOTHERAPY; SAMPLING PROTOCOL; SCHISTOSOMA MANSONI; STOCHASTIC RE-SAMPLING; TANZANIA;

ANIMALS; ANTHELMINTICS; DRUG RESISTANCE; GENETIC VARIATION; GENOTYPE; HUMANS; PRAZIQUANTEL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SELECTION, GENETIC; TANZANIA;

EID: 84885485625     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2012.03.001     Document Type: Article

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