The impact of single versus mixed Schistosoma haematobium and S. mansoni infections on morbidity profiles amongst school-children in Taveta, Kenya

Acta Tropica

Volumn 128, Issue 2, 2013, Pages 309-317

  Gouvras, Anouk N ^a   Kariuki, Curtis ^b,e   Koukounari, Artemis ^c   Norton, Alice J ^a,f   Lange, Charles N ^b   Ireri, Edmund ^d   Fenwick, Alan ^a   Mkoji, Gerald M ^d   Webster, Joanne P ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF PRIMATE RESEARCH   (Kenya)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^e KENYA METHODIST UNIVERSITY   (Kenya)

^f WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Coinfections; Human morbidity; Kenya; Polyparasitism; Schistosoma haematobium; Schistosoma mansoni; Schistosomiasis

Indexed keywords

ALBUMIN; PRAZIQUANTEL;

CHILD CARE; CHILD HEALTH; DISEASE; MORBIDITY; PATHOLOGY;

ADOLESCENT; ADULT; ARTICLE; BLADDER; CHILD; CLINICAL EXAMINATION; CONTROLLED STUDY; ECHOGRAPHY; ELEMENTARY STUDENT; FEMALE; FOLLOW UP; HUMAN; KENYA; LIVER; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MORBIDITY; PALPATION; PRESCHOOL CHILD; SCHISTOSOMA HEMATOBIUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS HAEMATOBIA; SCHISTOSOMIASIS MANSONI; SCHOOL CHILD; SPLEEN; URINALYSIS; UROGENITAL TRACT INFECTION;

KENYA;

SCHISTOSOMA; SCHISTOSOMA HAEMATOBIUM; SCHISTOSOMA MANSONI;

COINFECTIONS; HUMAN MORBIDITY; KENYA; POLYPARASITISM; SCHISTOSOMA HAEMATOBIUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS;

ADOLESCENT; ALBUMINS; ANIMALS; ANTHELMINTICS; CHILD; CHILD, PRESCHOOL; COINFECTION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; KENYA; LIVER; MALE; PRAZIQUANTEL; SCHISTOSOMA HAEMATOBIUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS HAEMATOBIA; SCHISTOSOMIASIS MANSONI; SPLEEN; URINARY BLADDER; URINE; YOUNG ADULT;

EID: 84885481358     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2013.01.001     Document Type: Article

References (33)

1. Abdelwahab M.F., Esmat G., Ramzy I., Fouad R., Abdelrahman M., Yosery A., Narooz S., Strickland G.T. Schistosoma haematobium infection in Egyptian schoolchildren-demonstration of both hepatic and urinary-tract morbidity by ultrasonography. Trans. R. Soc. Trop. Med. Hyg. 1992, 86:406-409.
2. Booth M., Vennervald B.J., Butterworth A.E., Kariuki H.C., Amaganga C., Kimani G., Mwatha J.K., Otedo A., Ouma J.H., Dunne D.W. Exposure to malaria affects the regression of hepatosplenomegaly after treatment for Schistosoma mansoni infection in Kenyan children. BMC Med. 2004, 2:36.
3. Booth M., Vennervald B.J., Kenty L., Butterworth A.E., Kariuki H.C., Kadzo H., Ireri E., Amaganga C., Kimani G., Mwatha J.K., Otedo A., Ouma J.H., Muchiri E., Dunne D.W. Micro-geographical variation in exposure to Schistosoma mansoni and malaria, and exacerbation of splenomegaly in Kenyan school-aged children. BMC Infect. Dis. 2004, 4:13.
4. Botelho M., Ferreira A.C., Oliveira M.J., Domingues A., Machado J.C., da Costa J.M.C. Schistosoma haematobium total antigen induces increased proliferation, migration and invasion, and decreases apoptosis of normal epithelial cells. Int. J. Parasitol. 2009, 39:1083-1091.
5. Botelho M., Oliveira P., Gomes J., Gartner F., Lopes C., da Costa J.M.C., Machado J.C. Tumourigenic effect of Schistosoma haematobium total antigen in mammalian cells. Int. J. Exp. Pathol. 2009, 90:448-453.
6. Briand V., Watier L., Jy L.E.H., Garcia A., Cot M. Coinfection with Plasmodium falciparum and Schistosoma haematobium: protective effect of schistosomiasis on malaria in senegalese children?. Am. J. Trop. Med. Hyg. 2005, 72:702-707.
7. Cunin P., Tchuem Tchuenté L.A., Poste B., Djibrilla K., Martin P.M. Interactions between Schistosoma haematobium and Schistosoma mansoni in humans in north Cameroon. Trop. Med. Int. Health 2003, 8:1110-1117.
8. Ernould J.C., Ba K., Sellin B. Increase of intestinal schistosomiasis after praziquantel treatment in a Schistosoma haematobium and Schistosoma mansoni mixed focus. Acta Trop. 1999, 73:143-152.
9. Fleming F.M., Brooker S., Geiger S.M., Caldas I.R., Correa-Oliveira R., Hotez P.J., Bethony J.M. Synergistic associations between hookworm and other helminth species in a rural community in Brazil. Trop. Med. Int. Health 2006, 11:56-64.
10. Friis H., Ndhlovu P., Kaondera K., Franke D., Vennervald B.J., Christensen N.O., Doehring E. Ultrasonographic assessment of Schistosoma mansoni and S. haematobium morbidity in Zimbabwean schoolchildren. Am. J. Trop. Med. Hyg. 1996, 55:290-294.
11. Fulford A.J. Dispersion and bias: can we trust geometric means?. Parasitol Today 1994, 10:446-448.
12. Gong Y.Y., Wilson S., Mwatha J.K., Routledge M.N., Castelino J.M., Zhao B., Kimani G., Kariuki H.C., Vennervald B.J., Dunne D.W., Wild C.P. Aflatoxin exposure may contribute to chronic hepatomegaly in Kenyan school children. Environ. Health Perspect. 2012, 120:893-896.
13. Haroun E.M., Hillyer G.V. Cross-resistance between Schistosoma mansoni and Fasciola hepatica in Sheep. J. Parasitol. 1988, 74:790-795.
14. Helmby H., Kullberg M., Troye-Blomberg M. Altered immune responses in mice with concomitant Schistosoma mansoni and Plasmodium chabaudi infections. Infect. Immun. 1998, 66:5167-5174.
15. Hillyer G.V. Immunity to schistosomes using heterologous trematode antigens-a review. Vet. Parasitol. 1984, 14:263-283.
16. Hillyer G.V. Fasciola antigens as vaccines against fascioliasis and schistosomiasis. J. Helminthol. 2005, 79:241-247.
17. Katz N., Chaves A., Pellegrino J. A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni. Rev. Inst. Med. Trop. São Paulo 1972, 14:397-400.
18. King C.H., Dangerfield-Cha M. The unacknowledged impact of chronic schistosomiasis. Chronic Illn. 2008, 4:65-79.
19. Koukounari A., Donnelly C.A., Sacko M., Keita A.D., Landoure A., Dembele R., Bosque-Oliva E., Gabrielli A.F., Gouvras A., Traore M., Fenwick A., Webster J.P. The impact of single versus mixed schistosome species infections on liver, spleen and bladder morbidity within Malian children pre- and post-praziquantel treatment. BMC Infect. Dis. 2010, 10:227.
20. Montresor A. Arithmetic or geometric means of eggs per gram are not appropriate indicators to estimate the impact of control measures in helminth infections. Trans. R Soc. Trop. Med. Hyg. 2007, 101:773-776.
21. Mott K.E., Baltes R., Bambagha J., Baldassini B. Field studies of a reusable polyamide filter for detection of Schistosoma haematobium eggs by urine filtration. Tropenmed. Parasitol. 1982, 33:227-228.
22. Murray H.W., Berman J.D., Davies C.R., Saravia N.G. Advances in leishmaniasis. Lancet 2005, 366:1561-1577.
23. Mwatha J.K., Jones F.M., Mohamed G., Naus C.W., Riley E.M., Butterworth A.E., Kimani G., Kariuki C.H., Ouma J.H., Koech D., Dunne D.W. Associations between anti-Schistosoma mansoni and anti-Plasmodium falciparum antibody responses and hepatosplenomegaly, in Kenyan schoolchildren. J. Infect. Dis. 2003, 187:1337-1341.
24. Nafeh M.A., Medhat A., Swifae Y., Moftah F.M., Mohamed A., Soliman A.G.A., Strickland G.T. Ultrasonographic changes of the liver in Schistosoma haematobium infection. Am. J. Trop. Med. Hyg. 1992, 47:225-230.
25. Richter J., Hatz C., Campagne G., Bergquist N.R., Jenkins J.M. Ultrasound in Schistosomiasis: A Practical Guide to the Standardized Use of Ultrasonography for Assessment of Schistosomiasis-Related Morbidity 2000, World Health Organization, Geneva, TDR/STR/SCH/00.1, 55.
26. Rollinson D., Klinger E.V., Mgeni A.F., Khamis I.S., Stothard J.R. Urinary schistosomiasis on Zanzibar: application of two novel assays for the detection of excreted albumin and haemoglobin in urine. J. Helminthol. 2005, 79:199-206.
27. Rowe D.J., Dawnay A., Watts G.F. Microalbuminuria in diabetes mellitus: review and recommendations for the measurement of albumin in urine. Annals Clin. Biochem. 1990, 27(Pt 4):297-312.
28. Steinmann P., Keiser J., Bos R., Tanner M., Utzinger J. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infect. Dis. 2006, 6:411-425.
29. van der Werf M.J., de Vlas S.K., Brooker S., Looman C.W.N., Nagelkerke N.J.D., Habbema J.D.F., Engels D. Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa. Acta Trop. 2003, 86:125-139.
30. Vennervald B.J., Kenty L., Butterworth A.E., Kariuki C.H., Kadzo H., Ireri E., Amaganga C., Kimani G., Mwatha J., Otedo A., Booth M., Ouma J.H., Dunne D.W. Detailed clinical and ultrasound examination of children and adolescents in a Schistosoma mansoni endemic area in Kenya: hepatosplenic disease in the absence of portal fibrosis. Trop. Med. Int. Health 2004, 90:461-470.
31. WHO Prevention and control of schistosomiasis and soil-transmitted helminthiasis. WHO Tech. Rep. Ser. 2002, 912:1-57.
32. Wilson S., Vennervald B.J., Kadzo H., Ireri E., Amaganga C., Booth M., Kariuki H.C., Mwatha J.K., Kimani G., Ouma J.H., Muchiri E., Dunne D.W. Health implications of chronic hepatosplenomegaly in Kenyan school-aged children chronically exposed to malarial infections and Schistosoma mansoni. Trans. R. Soc. Trop. Med. Hyg. 2010, 104:110-116.
33. Yagi A.I., Younis S.A., Haroun E.M., Gameel A.A., Bushara H.O., Taylor M.G. Studies on heterologous resistance between Schistosoma bovis and Fasciola gigantica in Sudanese Cattle. J. Helminthol. 1986, 60:55-59.