CD8+ memory T cells appear exhausted within hours of acute virus infection

Journal of Immunology

Volumn 191, Issue 8, 2013, Pages 4211-4222

  Hosking, Martin P ^a   Flynn, Claudia T ^a   Botten, Jason ^b   Whitton, J Lindsay ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; INTERLEUKIN 2; TRANSCRIPTION FACTOR T BET; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DISEASE ASSOCIATION; IN VIVO STUDY; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; MALE; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T CELL EXHAUSTION; VIRUS INFECTION; VIRUS REPLICATION;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; COSTIMULATORY AND INHIBITORY T-CELL RECEPTORS; DOWN-REGULATION; IMMUNOLOGIC MEMORY; INTERFERON-GAMMA; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POXVIRIDAE INFECTIONS; SPLEEN; TUMOR NECROSIS FACTORS; UP-REGULATION; VACCINIA VIRUS;

EID: 84885461706     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1300920     Document Type: Article

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