Enantioselective Ketone Hydrogenation: From Research to Pilot Scale with Industrially Viable Ru-(Phosphine-Oxazoline) Complexes

Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions: Second Edition

Volumn , Issue , 2010, Pages 321-329

  Naud, Frédéric ^a   Spindler, Felix ^a   Rueggeberg, Carsten ^b   Schmidt, Andreas T ^b   Blaser, Hans Ulrich ^a  

^a SOLVIAS AG   (Switzerland)

^b Rohner AG   (Switzerland)

Author keywords

Enantioselective hydrogenation; Ketones; Phosphine oxazoline complex catalyst; Ruthenium complex catalyst

Indexed keywords

EID: 84885430084     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527630639.ch19     Document Type: Chapter

References (12)

1. Ohkuma, T., Kitamura, M., and Noyori, R. (2000) in Catalytic Asymmetric Synthesis, 2nd edn (ed. I.Ojima), Wiley-VCH Verlag GmbH, Weinheim, p. 1..
2. Ohkuma, T. and Noyori, R. (1999) in Comprehensive Asymmetric Catalysis (eds. E.N.Jacobsen, H. Yamamoto, and A. Pfaltz), Springer, Berlin, p. 199.
3. Noyori, R. and Hashiguchi, S. (1997) Acc. Chem. Res., 30, 97.
4. Palmer, M.J. and Wills, M. (1999) Tetrahedron: Asymmetry, 10, 2045.
5. Zassinovich, G., Mestroni, G., and Gladiali, S. (1992) Chem. Rev., 92, 1051.
6. Noyori, R. and Ohkuma, T. (2001) Angew. Chem. Int. Ed., 40, 40.
7. Rautenstrauch, V., Hoang-Cong, X., Churlaud, R., Abdur-Rashid, K., and Morris, R.H. (2003) Chem. Eur. J., 9, 4954.
8. Naud, F., Malan, C., Spindler, F., R̈uggeberg, C., Schmidt, A.T., and Blaser, H.U. (2006) Adv. Synth. Catal., 348, 47.
9. Hansen, K.B., Chilenski, J.R., Desmond, R., Devine, P.N., Grabowski, E.J.J., Heid, R., Kubryk, M., Mathre, D.J., and Varsolona, R. (2003) Tetrahedron: Asymmetry, 14, 3581.
10. Welch, C.J., Albaneze-Walker, J., Leonard, W.R., Biba, M., DaSilva, J., Henderson, D., Laing, B., Mathre, D.J., Spencer, S., Bu, X., and Wang, T. (2005) Org. Process Res. Dev., 9, 198.
11. Johnson Matthey PGM Refining http://www.jmrefining.com/page-view.php?pageid=3&parentpageid=0.
12. Naud, F., Malan, C., Spindler, F., R̈uggeberg, C., Schmidt, A.T., and Blaser, H.U. (2007) Org. Process Res. Dev., 11, 519.