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Volumn 231, Issue 1, 2013, Pages 173-179

Homocysteine-related hTERT DNA demethylation contributes toshortened leukocyte telomere length in atherosclerosis

Author keywords

Atherosclerosis; DNA methyaltion; Homocysteine; HTERT; Leukocyte; Telomere length

Indexed keywords

C REACTIVE PROTEIN; CREATININE; CYANOCOBALAMIN; DNA; FOLIC ACID; HOMOCYSTEINE; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; TELOMERASE REVERSE TRANSCRIPTASE; TRIACYLGLYCEROL;

EID: 84885399790     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2013.08.029     Document Type: Article
Times cited : (39)

References (36)
  • 1
    • 84876912049 scopus 로고    scopus 로고
    • The roles of senescence and telomere shortening in cardiovascular disease
    • Fyhrquist F., Saijonmaa O., Strandberg T. The roles of senescence and telomere shortening in cardiovascular disease. Nat Rev Cardiol 2013, 10:274-283.
    • (2013) Nat Rev Cardiol , vol.10 , pp. 274-283
    • Fyhrquist, F.1    Saijonmaa, O.2    Strandberg, T.3
  • 2
    • 77954315040 scopus 로고    scopus 로고
    • Leukocyte telomere length is associated with measures of subclinical atherosclerosis
    • Panayiotou A.G., Nicolaides A.N., Griffin M., et al. Leukocyte telomere length is associated with measures of subclinical atherosclerosis. Atherosclerosis 2010, 211:176-181.
    • (2010) Atherosclerosis , vol.211 , pp. 176-181
    • Panayiotou, A.G.1    Nicolaides, A.N.2    Griffin, M.3
  • 3
    • 52049086861 scopus 로고    scopus 로고
    • Homocysteine levels and leukocyte telomere length
    • Richards J.B., Valdes A.M., Gardner J.P., et al. Homocysteine levels and leukocyte telomere length. Atherosclerosis 2008, 200:271-277.
    • (2008) Atherosclerosis , vol.200 , pp. 271-277
    • Richards, J.B.1    Valdes, A.M.2    Gardner, J.P.3
  • 4
    • 41149110120 scopus 로고    scopus 로고
    • Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study
    • Vasan R.S., Demissie S., Kimura M., et al. Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. Circulation 2008, 117:1138-1144.
    • (2008) Circulation , vol.117 , pp. 1138-1144
    • Vasan, R.S.1    Demissie, S.2    Kimura, M.3
  • 5
    • 77955890932 scopus 로고    scopus 로고
    • Effect of healthy lifestyle behaviors on the association between leukocyte telomere length and coronary artery calcium
    • Diaz V.A., Mainous A.R., Everett C.J., Schoepf U.J., Codd V., Samani N.J. Effect of healthy lifestyle behaviors on the association between leukocyte telomere length and coronary artery calcium. Am J Cardiol 2010, 106:659-663.
    • (2010) Am J Cardiol , vol.106 , pp. 659-663
    • Diaz, V.A.1    Mainous, A.R.2    Everett, C.J.3    Schoepf, U.J.4    Codd, V.5    Samani, N.J.6
  • 6
    • 79957789230 scopus 로고    scopus 로고
    • Leukocyte telomere length and mortality in the Cardiovascular Health Study
    • Fitzpatrick A.L., Kronmal R.A., Kimura M., et al. Leukocyte telomere length and mortality in the Cardiovascular Health Study. JGerontol A Biol Sci Med Sci 2011, 66:421-429.
    • (2011) JGerontol A Biol Sci Med Sci , vol.66 , pp. 421-429
    • Fitzpatrick, A.L.1    Kronmal, R.A.2    Kimura, M.3
  • 7
    • 66149171509 scopus 로고    scopus 로고
    • Race/ethnicity and telomere length in the Multi-Ethnic Study of atherosclerosis
    • Diez R.A., Ranjit N., Jenny N.S., et al. Race/ethnicity and telomere length in the Multi-Ethnic Study of atherosclerosis. Aging Cell 2009, 8:251-257.
    • (2009) Aging Cell , vol.8 , pp. 251-257
    • Diez, R.A.1    Ranjit, N.2    Jenny, N.S.3
  • 8
    • 70349887763 scopus 로고    scopus 로고
    • Physiology nobel. U.S. researchers recognized for work on telomeres
    • Vogel G., Pennisi E. Physiology nobel. U.S. researchers recognized for work on telomeres. Science 2009, 326:212-213.
    • (2009) Science , vol.326 , pp. 212-213
    • Vogel, G.1    Pennisi, E.2
  • 9
    • 49749139661 scopus 로고    scopus 로고
    • Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers
    • Kyo S., Takakura M., Fujiwara T., Inoue M. Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers. Cancer Sci 2008, 99:1528-1538.
    • (2008) Cancer Sci , vol.99 , pp. 1528-1538
    • Kyo, S.1    Takakura, M.2    Fujiwara, T.3    Inoue, M.4
  • 10
    • 72949088625 scopus 로고    scopus 로고
    • TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116
    • Choi J.H., Min N.Y., Park J., et al. TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116. Biochem Biophys Res Commun 2010, 391:449-454.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 449-454
    • Choi, J.H.1    Min, N.Y.2    Park, J.3
  • 11
    • 0141788590 scopus 로고    scopus 로고
    • Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres
    • Guilleret I., Benhattar J. Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres. Exp Cell Res 2003, 289:326-334.
    • (2003) Exp Cell Res , vol.289 , pp. 326-334
    • Guilleret, I.1    Benhattar, J.2
  • 12
    • 25144473114 scopus 로고    scopus 로고
    • Role of hTERT in apoptosis of cervical cancer induced by histone deacetylase inhibitor
    • Wu P., Meng L., Wang H., et al. Role of hTERT in apoptosis of cervical cancer induced by histone deacetylase inhibitor. Biochem Biophys Res Commun 2005, 335:36-44.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 36-44
    • Wu, P.1    Meng, L.2    Wang, H.3
  • 13
    • 38749144011 scopus 로고    scopus 로고
    • Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells
    • Hajek M., Votruba I., Holy A., Krecmerova M., Tloust'Ova E. Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells. Biochem Pharmacol 2008, 75:965-972.
    • (2008) Biochem Pharmacol , vol.75 , pp. 965-972
    • Hajek, M.1    Votruba, I.2    Holy, A.3    Krecmerova, M.4    Tloust'Ova, E.5
  • 14
    • 84865569776 scopus 로고    scopus 로고
    • Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells
    • Zhang D., Chen Y., Xie X., et al. Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells. JMol Cell Cardiol 2012, 53:487-496.
    • (2012) JMol Cell Cardiol , vol.53 , pp. 487-496
    • Zhang, D.1    Chen, Y.2    Xie, X.3
  • 15
    • 84862817897 scopus 로고    scopus 로고
    • Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium invitro and invivo
    • Zhang D., Xie X., Chen Y., Hammock B.D., Kong W., Zhu Y. Homocysteine upregulates soluble epoxide hydrolase in vascular endothelium invitro and invivo. Circ Res 2012, 110:808-817.
    • (2012) Circ Res , vol.110 , pp. 808-817
    • Zhang, D.1    Xie, X.2    Chen, Y.3    Hammock, B.D.4    Kong, W.5    Zhu, Y.6
  • 17
    • 33646101264 scopus 로고    scopus 로고
    • Homocysteine accelerates senescence and reduces proliferation of endothelial progenitor cells
    • Zhu J.H., Chen J.Z., Wang X.X., Xie X.D., Sun J., Zhang F.R. Homocysteine accelerates senescence and reduces proliferation of endothelial progenitor cells. JMol Cell Cardiol 2006, 40:648-652.
    • (2006) JMol Cell Cardiol , vol.40 , pp. 648-652
    • Zhu, J.H.1    Chen, J.Z.2    Wang, X.X.3    Xie, X.D.4    Sun, J.5    Zhang, F.R.6
  • 18
    • 0034678050 scopus 로고    scopus 로고
    • Homocysteine accelerates endothelial cell senescence
    • Xu D., Neville R., Finkel T. Homocysteine accelerates endothelial cell senescence. Febs Lett 2000, 470:20-24.
    • (2000) Febs Lett , vol.470 , pp. 20-24
    • Xu, D.1    Neville, R.2    Finkel, T.3
  • 19
    • 77953808161 scopus 로고    scopus 로고
    • Effects of selaginellin on homocysteine-induced senescence in human umbilical vein endothelial cells
    • Wang C.J., Hu C.P., Xu K.P., Tan G.S., Li Y.J. Effects of selaginellin on homocysteine-induced senescence in human umbilical vein endothelial cells. JCardiovasc Pharmacol 2010, 55:560-566.
    • (2010) JCardiovasc Pharmacol , vol.55 , pp. 560-566
    • Wang, C.J.1    Hu, C.P.2    Xu, K.P.3    Tan, G.S.4    Li, Y.J.5
  • 20
    • 2342419515 scopus 로고    scopus 로고
    • Telomere measurement by quantitative PCR
    • Cawthon R.M. Telomere measurement by quantitative PCR. Nucleic Acids Res 2002, 30:e47.
    • (2002) Nucleic Acids Res , vol.30
    • Cawthon, R.M.1
  • 21
    • 84875216378 scopus 로고    scopus 로고
    • Relation between leukocyte telomere length and incident coronary heart disease events (from the 1995 Canadian Nova Scotia Health Survey)
    • Ye S., Shaffer J.A., Kang M.S., et al. Relation between leukocyte telomere length and incident coronary heart disease events (from the 1995 Canadian Nova Scotia Health Survey). Am J Cardiol 2013, 111:962-967.
    • (2013) Am J Cardiol , vol.111 , pp. 962-967
    • Ye, S.1    Shaffer, J.A.2    Kang, M.S.3
  • 22
    • 24344466208 scopus 로고    scopus 로고
    • Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells
    • Takakura M., Kyo S., Inoue M., Wright W.E., Shay J.W. Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells. Mol Cell Biol 2005, 25:8037-8043.
    • (2005) Mol Cell Biol , vol.25 , pp. 8037-8043
    • Takakura, M.1    Kyo, S.2    Inoue, M.3    Wright, W.E.4    Shay, J.W.5
  • 23
    • 78149415042 scopus 로고    scopus 로고
    • DNA methylation of the promoter of soluble epoxide hydrolase silences its expression by an SP-1-dependent mechanism
    • Zhang D., Ai D., Tanaka H., Hammock B.D., Zhu Y. DNA methylation of the promoter of soluble epoxide hydrolase silences its expression by an SP-1-dependent mechanism. Biochim Biophys Acta 2010, 1799:659-667.
    • (2010) Biochim Biophys Acta , vol.1799 , pp. 659-667
    • Zhang, D.1    Ai, D.2    Tanaka, H.3    Hammock, B.D.4    Zhu, Y.5
  • 24
    • 77955174668 scopus 로고    scopus 로고
    • Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk
    • Willeit P., Willeit J., Brandstatter A., et al. Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk. Arterioscler Thromb Vasc Biol 2010, 30:1649-1656.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1649-1656
    • Willeit, P.1    Willeit, J.2    Brandstatter, A.3
  • 25
    • 70349737901 scopus 로고    scopus 로고
    • Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity
    • Spyridopoulos I., Hoffmann J., Aicher A., et al. Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity. Circulation 2009, 120:1364-1372.
    • (2009) Circulation , vol.120 , pp. 1364-1372
    • Spyridopoulos, I.1    Hoffmann, J.2    Aicher, A.3
  • 26
    • 72649095772 scopus 로고    scopus 로고
    • Systemic telomere length and preclinical atherosclerosis: the Asklepios Study
    • De Meyer T., Rietzschel E.R., De Buyzere M.L., et al. Systemic telomere length and preclinical atherosclerosis: the Asklepios Study. Eur Heart J 2009, 30:3074-3081.
    • (2009) Eur Heart J , vol.30 , pp. 3074-3081
    • De Meyer, T.1    Rietzschel, E.R.2    De Buyzere, M.L.3
  • 27
    • 10344229954 scopus 로고    scopus 로고
    • Accelerated telomere shortening in response to life stress
    • Epel E.S., Blackburn E.H., Lin J., et al. Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci U S A 2004, 101:17312-17315.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17312-17315
    • Epel, E.S.1    Blackburn, E.H.2    Lin, J.3
  • 28
    • 23844517498 scopus 로고    scopus 로고
    • Obesity, cigarette smoking, and telomere length in women
    • Valdes A.M., Andrew T., Gardner J.P., et al. Obesity, cigarette smoking, and telomere length in women. Lancet 2005, 366:662-664.
    • (2005) Lancet , vol.366 , pp. 662-664
    • Valdes, A.M.1    Andrew, T.2    Gardner, J.P.3
  • 30
    • 59049085356 scopus 로고    scopus 로고
    • Homocysteine decreases platelet NO level via protein kinase C activation
    • Signorello M.G., Segantin A., Passalacqua M., Leoncini G. Homocysteine decreases platelet NO level via protein kinase C activation. Nitric Oxide 2009, 20:104-113.
    • (2009) Nitric Oxide , vol.20 , pp. 104-113
    • Signorello, M.G.1    Segantin, A.2    Passalacqua, M.3    Leoncini, G.4
  • 31
    • 36348971786 scopus 로고    scopus 로고
    • Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene
    • Jamaluddin M.D., Chen I., Yang F., et al. Homocysteine inhibits endothelial cell growth via DNA hypomethylation of the cyclin A gene. Blood 2007, 110:3648-3655.
    • (2007) Blood , vol.110 , pp. 3648-3655
    • Jamaluddin, M.D.1    Chen, I.2    Yang, F.3
  • 32
    • 77955352742 scopus 로고    scopus 로고
    • Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
    • Meeran S.M., Patel S.N., Tollefsbol T.O. Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. PLoS One 2010, 5:e11457.
    • (2010) PLoS One , vol.5
    • Meeran, S.M.1    Patel, S.N.2    Tollefsbol, T.O.3
  • 33
    • 34047137148 scopus 로고    scopus 로고
    • Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene
    • Renaud S., Loukinov D., Abdullaev Z., et al. Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene. Nucleic Acids Res 2007, 35:1245-1256.
    • (2007) Nucleic Acids Res , vol.35 , pp. 1245-1256
    • Renaud, S.1    Loukinov, D.2    Abdullaev, Z.3
  • 34
    • 29444435624 scopus 로고    scopus 로고
    • Differential cis-regulation of human versus mouse TERT gene expression invivo: identification of a human-specific repressive element
    • Horikawa I., Chiang Y.J., Patterson T., et al. Differential cis-regulation of human versus mouse TERT gene expression invivo: identification of a human-specific repressive element. Proc Natl Acad Sci U S A 2005, 102:18437-18442.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 18437-18442
    • Horikawa, I.1    Chiang, Y.J.2    Patterson, T.3
  • 35
    • 13944280970 scopus 로고    scopus 로고
    • Anovel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues
    • Ritz J.M., Kuhle O., Riethdorf S., et al. Anovel transgenic mouse model reveals humanlike regulation of an 8-kbp human TERT gene promoter fragment in normal and tumor tissues. Cancer Res 2005, 65:1187-1196.
    • (2005) Cancer Res , vol.65 , pp. 1187-1196
    • Ritz, J.M.1    Kuhle, O.2    Riethdorf, S.3
  • 36
    • 85027947257 scopus 로고    scopus 로고
    • Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy
    • Huzen J., Peeters W., de Boer R.A., et al. Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy. Arterioscler Thromb Vasc Biol 2011, 31:1219-1225.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1219-1225
    • Huzen, J.1    Peeters, W.2    de Boer, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.