Massive transfusion: Blood component ratios

Current Opinion in Hematology

Volumn 20, Issue 6, 2013, Pages 521-525

  Lal, Devika S ^a   Shaz, Beth H ^a  

^a NEW YORK BLOOD CENTER   (United States)

Author keywords

Massive transfusion; massive transfusion protocols; transfusion; trauma induced coagulopathy

Indexed keywords

ANTIFIBRINOLYTIC AGENT;

ARMY; BLEEDING; BLOOD CLOTTING DISORDER; BLOOD COMPONENT THERAPY; BLOOD TRANSFUSION; CLINICAL PROTOCOL; ERYTHROCYTE TRANSFUSION; HOSPITAL POLICY; HUMAN; INJURY SEVERITY; LABORATORY; OUTCOME ASSESSMENT; PLASMA TRANSFUSION; POINT OF CARE TESTING; PRIORITY JOURNAL; REVIEW; SURVIVAL; THROMBOCYTE TRANSFUSION; THROMBOELASTOGRAPHY;

BLOOD COMPONENT TRANSFUSION; CLINICAL PROTOCOLS; HEMORRHAGIC DISORDERS; HUMANS; WOUNDS AND INJURIES;

EID: 84885395626     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0b013e3283653982     Document Type: Review

References (16)

1. Malone DL, Hess JR, Fingerhut A. Massive transfusion practices around the globe and a suggestion for a common massive transfusion protocol. J Trauma 2006; 60:S91-S96.
2. Cotton BA, Au BK, Nunez TC, et al. Predefined massive transfusion protocols are associated with a reduction in organ failure and postinjury complications. J Trauma 2009; 66:41-49.
3. Shaz BH, Winkler AM, James AB, et al. Pathophysiology of early trauma induced coagulopathy: emerging evidence for hemodilution and coagulation factor depletion. J Trauma 2011; 70:1401-1407.
4. Borgman M, Spinella P, Perkins J, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma 2007; 63:805-813.
5. Duchesne J, Islam T, Stuke I, et al. Hemostatic resuscitation during surgery improves survival in patients with traumatic-induced coagulopathy. J Trauma 2009; 67:33-37.
6. Gunter OJ, Au B, Isbell J, et al. Optimizing outcomes in damage control resuscitation: identifying blood product ratios associated with improved survival. J Trauma 2008; 65:527-534.
7. Holcomb J, Wade C, Michalek J, et al. Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg 2008; 248:447-458.
8. Shaz B, Dente C, Nicolas J, et al. Increased number of coagulation products in relationship to red blood cell products transfused improves mortality in trauma patients. Transfusion 2010; 50:493-500.
9. Teixeira P, Inaba K, Shulman I, et al. Impact of plasma transfusion in massively transfused trauma patients. J Trauma 2009; 66:693-697.
10. Zink K, Sambasivan C, Holcomb J, et al. A high ratio of plasma and platelets to packed red blood cells in the first 6 h of massive transfusion improves outcomes in a large multicenter study. Am J Surg 2009; 197:565-570.
11. Dzik WH, Blajchman MA, Fergusson D, et al. Clinical review: Canadian national advisory committee on blood and blood products-massive transfusion consensus conference 2011: report of the panel. Criti Care 2011; 15:242.
12. Holcomb JB, del Junco DJ, Fox EE, et al. The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks. JAMA Surg 2013; 148:127-136.
13. Josephson CD, Glynn SA, Kleinman SH, et al. A multidisciplinary 'think tank': the top 10 clinical trial opportunities in transfusion medicine from the National Heart, Lung, and Blood Institute-sponsored 2009 state-of-the-science symposium. Transfusion 2011; 51:828-841.
14. Walsh M, Thomas SG, Howard JC, et al. Blood component therapy in trauma guided with the utilization of the perfusionist and thromboelastography. J Extra Corpor Technol 2011; 43:162-167.
15. Shakur H, Roberts I, Bautista R, et al. CRASH-2 trial collaborators: effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant hemorrhage (CRASH-2): a randomized, placebo-controlled trial. Lancet 2010; 376:23-32.
16. Morrison JJ, Dubose JJ, Rasmussen TE, Midwinter MJ. Military application of tranexamic acid in trauma emergency resuscitation (MATTERs) study. Arch Surg 2012; 147:113-119.