메뉴 건너뛰기




Volumn 12, Issue 11, 2013, Pages 1037-1038

The murky path to drug discovery in ALS becomes clearer

Author keywords

[No Author keywords available]

Indexed keywords

DEXPRAMIPEXOLE; DOPAMINE; LEVODOPA; RILUZOLE;

EID: 84885383793     PISSN: 14744422     EISSN: 14744465     Source Type: Journal    
DOI: 10.1016/S1474-4422(13)70224-2     Document Type: Letter
Times cited : (6)

References (13)
  • 1
    • 84885388013 scopus 로고    scopus 로고
    • Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial
    • for the EMPOWER investigators, published online Sept 23.
    • Cudkowicz M, van den Berg LH, Shefner JM, et al. Dexpramipexole versus placebo for patients with amyotrophic lateral sclerosis (EMPOWER): a randomised, double-blind, phase 3 trial. Lancet Neurol 2013, for the EMPOWER investigators, published online Sept 23. http://dx.doi.org/10.1016/S1474-4422(13)70221-7.
    • (2013) Lancet Neurol
    • Cudkowicz, M.1    van den Berg, L.H.2    Shefner, J.M.3
  • 2
    • 84875543467 scopus 로고    scopus 로고
    • The current and projected economic burden of Parkinson's disease in the United States
    • Kowal SL, Dall TM, Chakrabarti R, Storm MV, Jain A The current and projected economic burden of Parkinson's disease in the United States. Mov Disord 2013, 28:311-318.
    • (2013) Mov Disord , vol.28 , pp. 311-318
    • Kowal, S.L.1    Dall, T.M.2    Chakrabarti, R.3    Storm, M.V.4    Jain, A.5
  • 3
    • 0014208039 scopus 로고
    • Aromatic amino acids and modification of parkinsonism
    • Cotzias GC, Van Woert MH, Schiffer LM Aromatic amino acids and modification of parkinsonism. N Engl J Med 1967, 276:374-379.
    • (1967) N Engl J Med , vol.276 , pp. 374-379
    • Cotzias, G.C.1    Van Woert, M.H.2    Schiffer, L.M.3
  • 4
    • 0021111491 scopus 로고
    • The origin of "Awakenings"
    • Sacks O The origin of "Awakenings". Br Med J (Clin Res Ed) 1983, 287:1968-1969.
    • (1983) Br Med J (Clin Res Ed) , vol.287 , pp. 1968-1969
    • Sacks, O.1
  • 5
    • 0029977337 scopus 로고    scopus 로고
    • Dose-ranging study of riluzole in amyotrophic lateral sclerosis
    • Amyotrophic Lateral Sclerosis/Riluzole Study Group II
    • Lacomblez L, Bensimon G, Leigh PN, Guillet P, Meininger V Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Lancet 1996, 347:1425-1431. Amyotrophic Lateral Sclerosis/Riluzole Study Group II.
    • (1996) Lancet , vol.347 , pp. 1425-1431
    • Lacomblez, L.1    Bensimon, G.2    Leigh, P.N.3    Guillet, P.4    Meininger, V.5
  • 6
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • ALS/Riluzole Study Group
    • Bensimon G, Lacomblez L, Meininger V A controlled trial of riluzole in amyotrophic lateral sclerosis. N Engl J Med 1994, 330:585-591. ALS/Riluzole Study Group.
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 7
    • 39349107014 scopus 로고    scopus 로고
    • Design, power, and interpretation of studies in the standard murine model of ALS
    • Scott S, Kranz JE, Cole J, et al. Design, power, and interpretation of studies in the standard murine model of ALS. Amyotroph Lateral Scler 2008, 9:4-15.
    • (2008) Amyotroph Lateral Scler , vol.9 , pp. 4-15
    • Scott, S.1    Kranz, J.E.2    Cole, J.3
  • 8
    • 84856101199 scopus 로고    scopus 로고
    • The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis
    • Cudkowicz M, Bozik ME, Ingersoll EW, et al. The effects of dexpramipexole (KNS-760704) in individuals with amyotrophic lateral sclerosis. Nat Med 2011, 17:1652-1656.
    • (2011) Nat Med , vol.17 , pp. 1652-1656
    • Cudkowicz, M.1    Bozik, M.E.2    Ingersoll, E.W.3
  • 10
    • 33845418269 scopus 로고    scopus 로고
    • Selecting promising ALS therapies in clinical trials
    • Cheung YK, Gordon PH, Levin B Selecting promising ALS therapies in clinical trials. Neurology 2006, 67:1748-1751.
    • (2006) Neurology , vol.67 , pp. 1748-1751
    • Cheung, Y.K.1    Gordon, P.H.2    Levin, B.3
  • 11
    • 77952190999 scopus 로고    scopus 로고
    • Toward more efficient clinical trials for amyotrophic lateral sclerosis
    • Cudkowicz ME, Katz J, Moore DH, et al. Toward more efficient clinical trials for amyotrophic lateral sclerosis. Amyotroph Lateral Scler 2010, 11:259-265.
    • (2010) Amyotroph Lateral Scler , vol.11 , pp. 259-265
    • Cudkowicz, M.E.1    Katz, J.2    Moore, D.H.3
  • 12
    • 48349092132 scopus 로고    scopus 로고
    • A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS
    • Gordon PH, Cheung YK, Levin B, et al. A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. Amyotroph Lateral Scler 2008, 9:212-222.
    • (2008) Amyotroph Lateral Scler , vol.9 , pp. 212-222
    • Gordon, P.H.1    Cheung, Y.K.2    Levin, B.3
  • 13
    • 70249116820 scopus 로고    scopus 로고
    • Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
    • Kaufmann P, Thompson JL, Levy G, et al. Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III. Ann Neurol 2009, 66:235-244.
    • (2009) Ann Neurol , vol.66 , pp. 235-244
    • Kaufmann, P.1    Thompson, J.L.2    Levy, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.