First identification of KPC-2 and VIM-1 producing Klebsiella pneumoniae in Bulgaria

Diagnostic Microbiology and Infectious Disease

Volumn 77, Issue 3, 2013, Pages 252-253

  Markovska, Rumyana ^a   Schneider, Ines ^b   Stoeva, Temenuga ^c   Bojkova, Kalina ^c   Boyanova, Lyudmila ^a   Bauernfeind, Adolf ^b   Mitov, Ivan ^a  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b MICOER Institute   (Germany)

^c MEDICAL UNIVERSITY OF VARNA   (Bulgaria)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; BETA LACTAMASE; CARBAPENEM DERIVATIVE; TOBRAMYCIN; UNCLASSIFIED DRUG; VERONA INTEGRON ENCODED METALLO BETA LACTAMASE 1;

ADULT; ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; BLA CTX M 15 GENE; BLA KPC 2 GENE; BLA VIM 1 GENE; BULGARIA; CASE REPORT; CONTROLLED STUDY; ENZYME SYNTHESIS; FEMALE; GENE SEQUENCE; HUMAN; ISOELECTRIC FOCUSING; KLEBSIELLA PNEUMONIAE; LETTER; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RANDOM AMPLIFIED POLYMORPHIC DNA; REPLICON;

ADULT; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; BULGARIA; FEMALE; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOLECULAR TYPING; RANDOM AMPLIFIED POLYMORPHIC DNA TECHNIQUE;

EID: 84885383301     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2013.07.019     Document Type: Letter

References (12)

1. Carattoli A., Bertini A., Villa L., Falbo V., Hopkins K.L., Threlfall E.J. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 2005, 63:219-228.
2. Clinical and Laboratory Standards Institute (CLSI) Performance Standards for Antimicrobial Susceptibility Testing. Sixteenth Informational Supplement. Approve standard (M100-S21) 2011, CLSI, Wayne, PA.
3. Cuzon G., Naas T., Truong H., Villegas M.V., Wisell K.T., Carmeli Y., et al. Worldwide diversity of Klebsiella pneumoniae that produce beta-lactamase blaKPC-2 gene. Emerg Infect Dis 2010, 16:1349-1356.
4. Giakkoupi P., Papagiannitsis C.C., Miriagou V., Pappa O., Polemis M., Tryfinopoulou K., et al. An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009-10). J Antimicrob Chemother 2011, 66:1510-1513.
5. Markovska R., Schneider I., Keuleyan E., Sredkova M., Ivanova D., Markova B., et al. Extended-spectrum beta-lactamase producing Enterobacteriaceae in Bulgarian hospitals. Microb Drug Resist 2008, 14:119-128.
6. Nordmann P., Naas T., Poirel L. Global spread of carbapenemase-producing Enterobacteriaceae. Emerg Infect Dis 2011, 17(10):1791-1798.
7. Poirel L., Walsh T.R., Cuvillier V., Nordmann P. Multiplex PCR for detection of acquired carbapenemase genes. Diagn Microbiol Infect Dis 2011, 70:119-123.
8. Poirel L, Savov E, Nazli A, Trifonova A, Gergova I, Todovora I, et al. Outbreak of New Delhi metallo beta-lactamase-1 (NDM-1)-producing Escherichia coli isolates in a hospital in Bulgaria. 23rd ECCMID 2013, Berlin, Germany P1286.
9. Richter S.N., Frasson I., Franchin E., Bergo C., Lavezzo E., Barzon L., et al. KPC-mediated resistance in Klebsiella pneumoniae in two hospitals in Padua, Italy, June 2009-December 2011: massive spreading of a KPC-3-encoding plasmid and involvement of non-intensive care units. Gut Pathog 2012, 4-7.
10. Smith Moland E., Hanson N., Herrera V., Black J., Lockhart T., Hossain A., et al. Plasmid-mediated, carbapenem-hydrolysing β-lactamase, KPC-2, in Klebsiella pneumoniae isolates. J Antimicrob Chemother 2003, 51:711-714.
11. Steinmann J., Kaase M., Gatermann S., Popp W., Steinmann E., Damman M., et al. Outbreak due to a Klebsiella pneumoniae strain harbouring KPC-2 and VIM-1 in a German university hospital, July 2010 to January 2011. Euro Surveill 2011, 16(33):18. pii:19944.
12. Tofteland S., Naseer U., Lislevand J.H., Sundsfjord A., Samuelsen O. A long-term low-frequency hospital outbreak of KPC-producing Klebsiella pneumoniae involving intergenus plasmid diffusion and a persisting environmental reservoir. PLoS One 2013, 8:e59015.