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Volumn 14, Issue 10, 2013, Pages 19987-20018

Non-coding RNAs: The "dark matter" of cardiovascular pathophysiology

Author keywords

Heart pathophysiology; Long non coding RNA; MicroRNA; Non coding RNA; Vascular development; Vascular disease

Indexed keywords

CALCINEURIN; LONG UNTRANSLATED RNA; MICRORNA 1; MICRORNA 133; MICRORNA 143; MICRORNA 145; MICRORNA 195; MICRORNA 378; MICRORNA 98; MITOGEN ACTIVATED PROTEIN KINASE; MYOSIN HEAVY CHAIN; THYROID HORMONE; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR SP1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

EID: 84885361567     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms141019987     Document Type: Review
Times cited : (51)

References (157)
  • 3
    • 3042767202 scopus 로고    scopus 로고
    • MicroRNAs: Small RNAs with a big role in gene regulation
    • He, L.; Hannon, G.J. MicroRNAs: Small RNAs with a big role in gene regulation. Nat. Rev. Genet. 2004, 5, 522-531.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 522-531
    • He, L.1    Hannon, G.J.2
  • 4
    • 60349120914 scopus 로고    scopus 로고
    • Long non-coding RNAs insight into functions
    • Mercer, T.R.; Dinger, M.E.; Mattick, J.S. Long non-coding RNAs insight into functions. Nat. Rev. Genet. 2009, 10, 155-159.
    • (2009) Nat. Rev. Genet , vol.10 , pp. 155-159
    • Mercer, T.R.1    Dinger, M.E.2    Mattick, J.S.3
  • 5
    • 84875183056 scopus 로고    scopus 로고
    • Structure and function of long noncoding RNAs in epigenetic regulation
    • Mercer, T.R.; Mattick, J.S. Structure and function of long noncoding RNAs in epigenetic regulation. Nat. Struct. Mol. Biol. 2013, 20, 300-307.
    • (2013) Nat. Struct. Mol. Biol , vol.20 , pp. 300-307
    • Mercer, T.R.1    Mattick, J.S.2
  • 6
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller, M. Non-coding RNAs in human disease. Nat. Rev. Genet. 2011, 12, 861-874.
    • (2011) Nat. Rev. Genet. , vol.12 , pp. 861-874
    • Esteller, M.1
  • 7
    • 54149090275 scopus 로고    scopus 로고
    • World Health Organization, WHO: Geneva, Switzerland
    • World Health Organization. The Global Burden of Disease 2004 Update. WHO: Geneva, Switzerland, 2008.
    • (2008) The Global Burden of Disease 2004 Update
  • 8
    • 78751660177 scopus 로고    scopus 로고
    • Pervasive roles of microRNAs in cardiovascular biology
    • Small, E.M.; Olson, E.N. Pervasive roles of microRNAs in cardiovascular biology. Nature 2011, 469, 336-342.
    • (2011) Nature , vol.469 , pp. 336-342
    • Small, E.M.1    Olson, E.N.2
  • 10
    • 84856136800 scopus 로고    scopus 로고
    • Recent studies of the human chromosome 9p21 locus, which is associated with atherosclerosis in human populations
    • Holdt, L.M.; Teupser, D. Recent studies of the human chromosome 9p21 locus, which is associated with atherosclerosis in human populations. Arterioscler. Thromb. Vasc. Biol. 2012, 32, 196-206.
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 196-206
    • Holdt, L.M.1    Teupser, D.2
  • 11
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros, V. The functions of animal microRNAs. Nature 2004, 431, 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 12
    • 77649253288 scopus 로고    scopus 로고
    • MicroRNAs add a new dimension to cardiovascular disease
    • Small, E.M.; Frost, R.J.; Olson, E.N. MicroRNAs add a new dimension to cardiovascular disease. Circulation 2010, 121, 1022-1032.
    • (2010) Circulation , vol.121 , pp. 1022-1032
    • Small, E.M.1    Frost, R.J.2    Olson, E.N.3
  • 13
    • 84875200257 scopus 로고    scopus 로고
    • Long noncoding RNAs: Cellular address codes in development and disease
    • Batista, P.J.; Chang, H.Y. Long noncoding RNAs: Cellular address codes in development and disease. Cell 2013, 152, 1298-1307.
    • (2013) Cell , vol.152 , pp. 1298-1307
    • Batista, P.J.1    Chang, H.Y.2
  • 14
    • 78649339069 scopus 로고    scopus 로고
    • Long noncoding RNA in genome regulation: Prospects and mechanisms
    • Hung, T.; Chang, H.Y. Long noncoding RNA in genome regulation: Prospects and mechanisms. RNA Biol. 2010, 7, 582-585.
    • (2010) RNA Biol. , vol.7 , pp. 582-585
    • Hung, T.1    Chang, H.Y.2
  • 16
    • 84866927722 scopus 로고    scopus 로고
    • The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart
    • Korostowski, L.; Sedlak, N.; Engel, N. The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart. PLoS Genet. 2012, 8, e1002956.
    • (2012) PLoS Genet. , vol.8
    • Korostowski, L.1    Sedlak, N.2    Engel, N.3
  • 18
    • 27944508215 scopus 로고    scopus 로고
    • CLIP: A method for identifying protein-RNA interaction sites in living cells
    • Ule, J.; Jensen, K.; Mele, A.; Darnell, R.B. CLIP: A method for identifying protein-RNA interaction sites in living cells. Methods 2005, 37, 376-386.
    • (2005) Methods , vol.37 , pp. 376-386
    • Ule, J.1    Jensen, K.2    Mele, A.3    Darnell, R.B.4
  • 20
    • 84555189622 scopus 로고    scopus 로고
    • Analysis of co-transcriptional RNA processing by RNA-ChIP assay
    • Bittencourt, D.; Auboeuf, D. Analysis of co-transcriptional RNA processing by RNA-ChIP assay. Methods Mol. Biol. 2012, 809, 563-577.
    • (2012) Methods Mol. Biol , vol.809 , pp. 563-577
    • Bittencourt, D.1    Auboeuf, D.2
  • 21
    • 84255160602 scopus 로고    scopus 로고
    • Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation
    • Hu, W.; Yuan, B.; Flygare, J.; Lodish, H.F. Long noncoding RNA-mediated anti-apoptotic activity in murine erythroid terminal differentiation. Genes Dev. 2011, 25, 2573-2578.
    • (2011) Genes Dev , vol.25 , pp. 2573-2578
    • Hu, W.1    Yuan, B.2    Flygare, J.3    Lodish, H.F.4
  • 22
    • 78651305638 scopus 로고    scopus 로고
    • Mining Affymetrix microarray data for long non-coding RNAs: Altered expression in the nucleus accumbens of heroin abusers
    • Michelhaugh, S.K.; Lipovich, L.; Blythe, J.; Jia, H.; Kapatos, G.; Bannon, M.J. Mining Affymetrix microarray data for long non-coding RNAs: Altered expression in the nucleus accumbens of heroin abusers. J. Neurochem. 2011, 116, 459-466.
    • (2011) J. Neurochem , vol.116 , pp. 459-466
    • Michelhaugh, S.K.1    Lipovich, L.2    Blythe, J.3    Jia, H.4    Kapatos, G.5    Bannon, M.J.6
  • 26
  • 34
    • 77953957633 scopus 로고    scopus 로고
    • A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno, L.; Salmena, L.; Zhang, J.; Carver, B.; Haveman, W.J.; Pandolfi, P.P. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010, 465, 1033-1038.
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 37
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson, G.K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med. 2005, 352, 1685-1695.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 39
    • 79957784091 scopus 로고    scopus 로고
    • Mechanisms of smooth muscle cell proliferation and endothelial regeneration after vascular injury and stenting: Approach to therapy
    • Curcio, A.; Torella, D.; Indolfi, C. Mechanisms of smooth muscle cell proliferation and endothelial regeneration after vascular injury and stenting: Approach to therapy. Circ. J. 2011, 75, 1287-1296.
    • (2011) Circ. J. , vol.75 , pp. 1287-1296
    • Curcio, A.1    Torella, D.2    Indolfi, C.3
  • 40
    • 34447632218 scopus 로고    scopus 로고
    • Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis
    • Kuehbacher, A.; Urbich, C.; Zeiher, A.M.; Dimmeler, S. Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis. Circ. Res. 2007, 101, 59-68.
    • (2007) Circ. Res. , vol.101 , pp. 59-68
    • Kuehbacher, A.1    Urbich, C.2    Zeiher, A.M.3    Dimmeler, S.4
  • 41
    • 34247554263 scopus 로고    scopus 로고
    • Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells
    • Suárez, Y.; Fernández-Hernando, C.; Pober, J.S.; Sessa, W.C. Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells. Circ. Res. 2007, 100, 1164-1173.
    • (2007) Circ. Res. , vol.100 , pp. 1164-1173
    • Suárez, Y.1    Fernández-Hernando, C.2    Pober, J.S.3    Sessa, W.C.4
  • 42
    • 52449100144 scopus 로고    scopus 로고
    • Role of microRNAs in vascular diseases, inflammation, and angiogenesis
    • Urbich, C.; Kuehbacher, A.; Dimmeler, S. Role of microRNAs in vascular diseases, inflammation, and angiogenesis. Cardiovasc. Res. 2008, 79, 581-588.
    • (2008) Cardiovasc. Res. , vol.79 , pp. 581-588
    • Urbich, C.1    Kuehbacher, A.2    Dimmeler, S.3
  • 45
    • 74849101761 scopus 로고    scopus 로고
    • The microRNA-17-92 cluster: Still a miRacle?
    • Bonauer, A.; Dimmeler, S. The microRNA-17-92 cluster: Still a miRacle? Cell Cycle 2009, 8, 3866-3873.
    • (2009) Cell Cycle , vol.8 , pp. 3866-3873
    • Bonauer, A.1    Dimmeler, S.2
  • 47
    • 84858701910 scopus 로고    scopus 로고
    • Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium
    • Fang, Y.; Davies, P.F. Site-specific microRNA-92a regulation of Kruppel-like factors 4 and 2 in atherosusceptible endothelium. Arterioscler. Thromb. Vasc. Biol. 2012, 32, 979-987.
    • (2012) Arterioscler. Thromb. Vasc. Biol. , vol.32 , pp. 979-987
    • Fang, Y.1    Davies, P.F.2
  • 51
    • 84864827128 scopus 로고    scopus 로고
    • Inhibition of mir-92a increases endothelial proliferation and migration in vitro as well as reduces neointimal proliferation in vivo after vascular injury
    • doi:10.1007/s00395-012-0296-y
    • Iaconetti, C.; Polimeni, A.; Sorrentino, S.; Sabatino, J.; Pironti, G.; Esposito, G.; Curcio, A.; Indolfi, C. Inhibition of mir-92a increases endothelial proliferation and migration in vitro as well as reduces neointimal proliferation in vivo after vascular injury. Basic Res. Cardiol. 2012, 107, doi:10.1007/s00395-012-0296-y.
    • (2012) Basic Res. Cardiol. , vol.107
    • Iaconetti, C.1    Polimeni, A.2    Sorrentino, S.3    Sabatino, J.4    Pironti, G.5    Esposito, G.6    Curcio, A.7    Indolfi, C.8
  • 52
    • 0036955020 scopus 로고    scopus 로고
    • Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats
    • Indolfi, C.; Torella, D.; Coppola, C.; Curcio, A.; Rodriguez, F.; Bilancio, A.; Leccia, A.; Arcucci, O.; Falco, M.; Leosco, D.; et al. Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in rats. Circ. Res. 2002, 91, 1190-1197.
    • (2002) Circ. Res. , vol.91 , pp. 1190-1197
    • Indolfi, C.1    Torella, D.2    Coppola, C.3    Curcio, A.4    Rodriguez, F.5    Bilancio, A.6    Leccia, A.7    Arcucci, O.8    Falco, M.9    Leosco, D.10
  • 54
    • 79953057954 scopus 로고    scopus 로고
    • Endothelial enriched microRNAs regulate angiotensin II-induced endothelial inflammation and migration
    • Zhu, N.; Zhang, D.; Chen, S.; Liu, X.; Lin, L.; Huang, X.; Guo, Z.; Liu, J.; Wang, Y.; Yuan, W.; et al. Endothelial enriched microRNAs regulate angiotensin II-induced endothelial inflammation and migration. Atherosclerosis 2011, 215, 286-293.
    • (2011) Atherosclerosis , vol.215 , pp. 286-293
    • Zhu, N.1    Zhang, D.2    Chen, S.3    Liu, X.4    Lin, L.5    Huang, X.6    Guo, Z.7    Liu, J.8    Wang, Y.9    Yuan, W.10
  • 55
    • 24644482721 scopus 로고    scopus 로고
    • Ets-1 is a critical regulator of Ang IImediated vascular inflammation and remodeling
    • Zhan, Y.; Brown, C.; Maynard, E.; Anshelevich, A.; Ni, W.; Ho, I.C.; Oettgen, P. Ets-1 is a critical regulator of Ang IImediated vascular inflammation and remodeling. J. Clin. Investig. 2005, 115, 2508-2516.
    • (2005) J. Clin. Investig. , vol.115 , pp. 2508-2516
    • Zhan, Y.1    Brown, C.2    Maynard, E.3    Anshelevich, A.4    Ni, W.5    Ho, I.C.6    Oettgen, P.7
  • 56
    • 84870236071 scopus 로고    scopus 로고
    • Essential role of microRNA-155 in regulating endothelium-dependent vasorelaxation by targeting endothelial nitric oxide synthase
    • Sun, H.X.; Zeng, D.Y.; Li, R.T.; Pang, R.P.; Yang, H.; Hu, Y.L.; Zhang, Q.; Jiang, Y.; Huang, L.Y.; Tang, Y.B.; et al. Essential role of microRNA-155 in regulating endothelium-dependent vasorelaxation by targeting endothelial nitric oxide synthase. Hypertension 2012, 60, 1407-1414.
    • (2012) Hypertension , vol.60 , pp. 1407-1414
    • Sun, H.X.1    Zeng, D.Y.2    Li, R.T.3    Pang, R.P.4    Yang, H.5    Hu, Y.L.6    Zhang, Q.7    Jiang, Y.8    Huang, L.Y.9    Tang, Y.B.10
  • 57
    • 33745571976 scopus 로고    scopus 로고
    • The immune response in atherosclerosis: A double-edged sword
    • Hansson, G.K.; Libby, P. The immune response in atherosclerosis: A double-edged sword. Nat. Rev. Immunol. 2006, 6, 508-519.
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 508-519
    • Hansson, G.K.1    Libby, P.2
  • 60
    • 77955795714 scopus 로고    scopus 로고
    • MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro
    • Fang, Y.; Shi, C.; Manduchi, E.; Civelek, M.; Davies, P.F. MicroRNA-10a regulation of proinflammatory phenotype in athero-susceptible endothelium in vivo and in vitro. Proc. Natl. Acad. Sci. USA 2010, 107, 13450-13455.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 13450-13455
    • Fang, Y.1    Shi, C.2    Manduchi, E.3    Civelek, M.4    Davies, P.F.5
  • 61
    • 77954952398 scopus 로고    scopus 로고
    • MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells
    • Li, D.; Yang, P., Xiong, Q.; Song, X.; Yang, X.; Liu. L.; Yuan, W.; Rui, Y.C. MicroRNA-125a/b-5p inhibits endothelin-1 expression in vascular endothelial cells. J. Hypertens. 2010, 28, 1646-1654.
    • (2010) J. Hypertens. , vol.28 , pp. 1646-1654
    • Li, D.1    Yang, P.2    Xiong, Q.3    Song, X.4    Yang, X.5    Liu, L.6    Yuan, W.7    Rui, Y.C.8
  • 62
    • 84865428817 scopus 로고    scopus 로고
    • Pathophysiological roles of endothelin receptors in cardiovascular diseases
    • Ohkita, M.; Tawa, M.; Kitada, K.; Matsumura, Y. Pathophysiological roles of endothelin receptors in cardiovascular diseases. J. Pharmacol. Sci. 2012, 119, 302-313.
    • (2012) J. Pharmacol. Sci. , vol.119 , pp. 302-313
    • Ohkita, M.1    Tawa, M.2    Kitada, K.3    Matsumura, Y.4
  • 63
    • 84857293493 scopus 로고    scopus 로고
    • Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease
    • Alexander, M.R.; Owens, G.K. Epigenetic control of smooth muscle cell differentiation and phenotypic switching in vascular development and disease. Annu. Rev. Physiol. 2012, 74, 13-40.
    • (2012) Annu. Rev. Physiol , vol.74 , pp. 13-40
    • Alexander, M.R.1    Owens, G.K.2
  • 64
    • 84862874414 scopus 로고    scopus 로고
    • Smooth muscle cell phenotypic switching in atherosclerosis
    • Gomez, D.; Owens, G.K. Smooth muscle cell phenotypic switching in atherosclerosis. Cardiovasc. Res. 2012, 95, 156-164.
    • (2012) Cardiovasc. Res. , vol.95 , pp. 156-164
    • Gomez, D.1    Owens, G.K.2
  • 65
    • 0035895594 scopus 로고    scopus 로고
    • Membrane-bound protein kinase A inhibits smooth muscle cell proliferation in vitro and in vivo by amplifying cAMP-protein kinase A signals
    • Indolfi, C.; Stabile, E.; Coppola, C.; Gallo, A.; Perrino, C.; Allevato, G.; Cavuto, L.; Torella, D.; Di Lorenzo, E.; Troncone, G.; et al. Membrane-bound protein kinase A inhibits smooth muscle cell proliferation in vitro and in vivo by amplifying cAMP-protein kinase A signals. Circ. Res. 2001, 88, 319-324.
    • (2001) Circ. Res. , vol.88 , pp. 319-324
    • Indolfi, C.1    Stabile, E.2    Coppola, C.3    Gallo, A.4    Perrino, C.5    Allevato, G.6    Cavuto, L.7    Torella, D.8    Di Lorenzo, E.9    Troncone, G.10
  • 68
    • 68049083397 scopus 로고    scopus 로고
    • MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation
    • Cheng, Y.; Liu, X.; Yang, J.; Lin, Y.; Xu, D.Z.; Lu, Q.; Deitch, E.A.; Huo, Y.; Delphin, E.S.; Zhang, C. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ. Res. 2009, 105, 158-166.
    • (2009) Circ. Res. , vol.105 , pp. 158-166
    • Cheng, Y.1    Liu, X.2    Yang, J.3    Lin, Y.4    Xu, D.Z.5    Lu, Q.6    Deitch, E.A.7    Huo, Y.8    Delphin, E.S.9    Zhang, C.10
  • 70
    • 40949138254 scopus 로고    scopus 로고
    • Molecular control of vascular smooth muscle cell differentiation and phenotypic plasticity
    • Owens, G.K. Molecular control of vascular smooth muscle cell differentiation and phenotypic plasticity. Novartis Found Symp. 2007, 283, 174-191.
    • (2007) Novartis Found Symp. , vol.283 , pp. 174-191
    • Owens, G.K.1
  • 71
    • 77950564432 scopus 로고    scopus 로고
    • MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro
    • Quintavalle, M.; Elia, L.; Condorelli, G.; Courtneidge, S.A. MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro. J. Cell Biol. 2010, 189, 13-22.
    • (2010) J. Cell Biol. , vol.189 , pp. 13-22
    • Quintavalle, M.1    Elia, L.2    Condorelli, G.3    Courtneidge, S.A.4
  • 72
    • 37549065952 scopus 로고    scopus 로고
    • Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors
    • Lagna, G.; Ku, M.M.; Nguyen, P.H.; Neuman, N.A.; Davis, B.N.; Hata, A. Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors. J. Biol. Chem. 2007, 282, 37244-37255.
    • (2007) J. Biol. Chem. , vol.282 , pp. 37244-37255
    • Lagna, G.1    Ku, M.M.2    Nguyen, P.H.3    Neuman, N.A.4    Davis, B.N.5    Hata, A.6
  • 73
    • 35448991324 scopus 로고    scopus 로고
    • Extracellular control of TGFβ signalling in vascular development and disease
    • Ten Dijke, P.; Arthur, H.M. Extracellular control of TGFβ signalling in vascular development and disease. Nat. Rev. Mol. Cell Biol. 2007, 8, 857-869.
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 857-869
    • Ten Dijke, P.1    Arthur, H.M.2
  • 74
    • 0037837819 scopus 로고    scopus 로고
    • Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype
    • King, K.E.; Iyemere, V.P.; Weissberg, P.L.; Shanahan, C.M. Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype. J. Biol. Chem. 2003, 278, 11661-11669.
    • (2003) J. Biol. Chem. , vol.278 , pp. 11661-11669
    • King, K.E.1    Iyemere, V.P.2    Weissberg, P.L.3    Shanahan, C.M.4
  • 75
    • 80051532504 scopus 로고    scopus 로고
    • Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4
    • Davis-Dusenbery, B.N.; Chan, M.C.; Reno, K.E.; Weisman, A.S.; Layne, M.D.; Lagna, G.; Hata, A. Down-regulation of Kruppel-like factor-4 (KLF4) by microRNA-143/145 is critical for modulation of vascular smooth muscle cell phenotype by transforming growth factor-beta and bone morphogenetic protein 4. J. Biol. Chem. 2011, 286, 28097-28110.
    • (2011) J. Biol. Chem. , vol.286 , pp. 28097-28110
    • Davis-Dusenbery, B.N.1    Chan, M.C.2    Reno, K.E.3    Weisman, A.S.4    Layne, M.D.5    Lagna, G.6    Hata, A.7
  • 76
    • 66249114665 scopus 로고    scopus 로고
    • Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle
    • Deaton, R.A.; Gan, Q.; Owens, G.K. Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle. Am. J. Physiol. Heart Circ. Physiol. 2009, 296, 1027-1037.
    • (2009) Am. J. Physiol. Heart Circ. Physiol. , vol.296 , pp. 1027-1037
    • Deaton, R.A.1    Gan, Q.2    Owens, G.K.3
  • 78
    • 34250172419 scopus 로고    scopus 로고
    • MicroRNA expression signa-ture and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation
    • Ji, R.; Cheng, Y.; Yue, J.; Yang, J.; Liu, X.; Chen, H.; Dean, D.B.; Zhang, C. MicroRNA expression signa-ture and antisense-mediated depletion reveal an essential role of microRNA in vascular neointimal lesion formation. Circ. Res. 2007, 100, 1579-1588.
    • (2007) Circ. Res , vol.100 , pp. 1579-1588
    • Ji, R.1    Cheng, Y.2    Yue, J.3    Yang, J.4    Liu, X.5    Chen, H.6    Dean, D.B.7    Zhang, C.8
  • 79
    • 61949252089 scopus 로고    scopus 로고
    • A necessary role of miR-221and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia
    • Liu, X.; Cheng, Y.; Zhang, S.; Lin, Y.; Yang, J.; Zhang, C. A necessary role of miR-221and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia. Circ. Res. 2009, 104, 476-487.
    • (2009) Circ. Res. , vol.104 , pp. 476-487
    • Liu, X.1    Cheng, Y.2    Zhang, S.3    Lin, Y.4    Yang, J.5    Zhang, C.6
  • 80
    • 78650897480 scopus 로고    scopus 로고
    • miR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth musclecell proliferation
    • Sun, S.G.; Zheng, B.; Han, M.; Fang, X.M.; Li, H.X.; Miao, S.B.; Su, M.; Han, Y.; Shi, H.J.; Wen, J.K. miR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth musclecell proliferation. EMBO Reports 2011, 12, 56-62.
    • (2011) EMBO Reports , vol.12 , pp. 56-62
    • Sun, S.G.1    Zheng, B.2    Han, M.3    Fang, X.M.4    Li, H.X.5    Miao, S.B.6    Su, M.7    Han, Y.8    Shi, H.J.9    Wen, J.K.10
  • 82
    • 63649147782 scopus 로고    scopus 로고
    • Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype
    • Davis, B.N.; Hilyard, A.C.; Nguyen, P.H.; Lagna, G.; Hata, A. Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J. Biol. Chem. 2009, 284, 3728-3738.
    • (2009) J. Biol. Chem , vol.284 , pp. 3728-3738
    • Davis, B.N.1    Hilyard, A.C.2    Nguyen, P.H.3    Lagna, G.4    Hata, A.5
  • 83
    • 77949668668 scopus 로고    scopus 로고
    • Role of Krüppel-like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells
    • Zheng, B.; Han, M.; Wen, J.K. Role of Krüppel-like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells. IUBMB Life 2010, 62, 132-139.
    • (2010) IUBMB Life , vol.62 , pp. 132-139
    • Zheng, B.1    Han, M.2    Wen, J.K.3
  • 86
    • 67349106068 scopus 로고    scopus 로고
    • MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4
    • Cheng, Y.; Liu, X.; Zhang, S.; Lin, Y.; Yang, J.; Zhang, C. MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4. J. Mol. Cell. Cardiol. 2009, 47, 5-14.
    • (2009) J. Mol. Cell. Cardiol. , vol.47 , pp. 5-14
    • Cheng, Y.1    Liu, X.2    Zhang, S.3    Lin, Y.4    Yang, J.5    Zhang, C.6
  • 87
    • 80052148252 scopus 로고    scopus 로고
    • MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities
    • Wang, M.; Li, W.; Chang, G.Q.; Ye, C.S.; Ou, J.S.; Li, X.X.; Liu, Y.; Cheang, T.Y.; Huang, X.L.; Wang, S.M. MicroRNA-21 regulates vascular smooth muscle cell function via targeting tropomyosin 1 in arteriosclerosis obliterans of lower extremities. Arterioscler. Thromb. Vasc. Biol. 2011, 31, 2044-2053.
    • (2011) Arterioscler. Thromb. Vasc. Biol , vol.31 , pp. 2044-2053
    • Wang, M.1    Li, W.2    Chang, G.Q.3    Ye, C.S.4    Ou, J.S.5    Li, X.X.6    Liu, Y.7    Cheang, T.Y.8    Huang, X.L.9    Wang, S.M.10
  • 90
    • 62349138052 scopus 로고    scopus 로고
    • MicroRNAs: Opening a new vein in angiogenesis research
    • doi:10.1126/scisignal.252pe1
    • Fish, J.E.; Srivastava, D. MicroRNAs: Opening a new vein in angiogenesis research. Sci. Signal. 2009, doi:10.1126/scisignal.252pe1.
    • (2009) Sci. Signal
    • Fish, J.E.1    Srivastava, D.2
  • 93
    • 84857020975 scopus 로고    scopus 로고
    • miR-221 is required for endothelial tip cell behaviors during vascular development
    • Nicoli, S.; Knyphausen, C.P.; Zhu, L.J.; Lakshmanan, A.; Lawson, N.D. miR-221 is required for endothelial tip cell behaviors during vascular development. Dev. Cell 2012, 22, 418-429.
    • (2012) Dev. Cell , vol.22 , pp. 418-429
    • Nicoli, S.1    Knyphausen, C.P.2    Zhu, L.J.3    Lakshmanan, A.4    Lawson, N.D.5
  • 95
    • 77951215303 scopus 로고    scopus 로고
    • miR-10a contributes to retinoid acid-induced smooth muscle cell differentiation
    • Huang, H.; Xie, C.; Sun, X.; Ritchie, R.P.; Zhang, J.; Chen, Y.E. miR-10a contributes to retinoid acid-induced smooth muscle cell differentiation. J. Biol. Chem. 2010, 285, 9383-9389.
    • (2010) J. Biol. Chem , vol.285 , pp. 9383-9389
    • Huang, H.1    Xie, C.2    Sun, X.3    Ritchie, R.P.4    Zhang, J.5    Chen, Y.E.6
  • 96
  • 97
    • 0037013163 scopus 로고    scopus 로고
    • Histone acetylation and recruitment of serum responsive factor and CREB-binding protein onto SM22 promoter during SM22 gene expression
    • Qiu, P.; Li, L. Histone acetylation and recruitment of serum responsive factor and CREB-binding protein onto SM22 promoter during SM22 gene expression. Circ. Res. 2002, 90, 858-865.
    • (2002) Circ. Res. , vol.90 , pp. 858-865
    • Qiu, P.1    Li, L.2
  • 99
    • 46449128469 scopus 로고    scopus 로고
    • SMAD proteins control DROSHA-mediated microRNA maturation
    • Davis, B.N.; Hilyard, A.C.; Lagna, G.; Hata, A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008, 454, 56-61.
    • (2008) Nature , vol.454 , pp. 56-61
    • Davis, B.N.1    Hilyard, A.C.2    Lagna, G.3    Hata, A.4
  • 102
    • 40549109924 scopus 로고    scopus 로고
    • PROCARDIS consortium. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
    • Broadbent, H.M.; Peden, J.F.; Lorkowski, S.; Goel, A.; Ongen, H.; Green, F.; Clarke, R.; Collins, R.; Franzosi, M.G.; Tognoni, G.; et al. PROCARDIS consortium. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. Hum. Mol. Genet. 2008, 17, 806-814.
    • (2008) Hum. Mol. Genet , vol.17 , pp. 806-814
    • Broadbent, H.M.1    Peden, J.F.2    Lorkowski, S.3    Goel, A.4    Ongen, H.5    Green, F.6    Clarke, R.7    Collins, R.8    Franzosi, M.G.9    Tognoni, G.10
  • 104
    • 77953096072 scopus 로고    scopus 로고
    • Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a
    • Yap, K.L.; Li, S.; Muñoz-Cabello, A.M.; Raguz, S.; Zeng, L.; Mujtaba, S.; Gil, J.; Walsh, M.J.; Zhou, M.M. Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a. Mol. Cell 2010, 38, 662-674.
    • (2010) Mol. Cell , vol.38 , pp. 662-674
    • Yap, K.L.1    Li, S.2    Muñoz-Cabello, A.M.3    Raguz, S.4    Zeng, L.5    Mujtaba, S.6    Gil, J.7    Walsh, M.J.8    Zhou, M.M.9
  • 106
    • 34447543034 scopus 로고    scopus 로고
    • Hypoxia-inducible expression of a natural cis-antisense transcript inhibits endothelial nitric-oxide synthase
    • Fish, J.E.; Matouk, C.C.; Yeboah, E.; Bevan, S.C.; Khan, M.; Patil, K.; Ohh, M.; Marsden, P.A. Hypoxia-inducible expression of a natural cis-antisense transcript inhibits endothelial nitric-oxide synthase. J. Biol. Chem. 2007, 282, 15652-15666.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15652-15666
    • Fish, J.E.1    Matouk, C.C.2    Yeboah, E.3    Bevan, S.C.4    Khan, M.5    Patil, K.6    Ohh, M.7    Marsden, P.A.8
  • 109
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Zhao, Y.; Samal, E.; Srivastava, D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 2005, 436, 214-220.
    • (2005) Nature , vol.436 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 112
    • 57749121689 scopus 로고    scopus 로고
    • microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart
    • Liu, N.; Bezprozvannaya, S.; Williams, A.H.; Qi, X.; Richardson, J.A.; Bassel-Duby, R.; Olson, E.N. microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev. 2008, 22, 3242-3254.
    • (2008) Genes Dev , vol.22 , pp. 3242-3254
    • Liu, N.1    Bezprozvannaya, S.2    Williams, A.H.3    Qi, X.4    Richardson, J.A.5    Bassel-Duby, R.6    Olson, E.N.7
  • 113
    • 64649094112 scopus 로고    scopus 로고
    • MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes
    • Ikeda, S.; He, A.; Kong, S.W.; Lu, J.; Bejar, R.; Bodyak, N.; Lee, K.H.; Ma, Q.; Kang, P.M.; Golub, T.R.; et al. MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol. Cell Biol. 2009, 29, 2193-2204.
    • (2009) Mol. Cell Biol , vol.29 , pp. 2193-2204
    • Ikeda, S.1    He, A.2    Kong, S.W.3    Lu, J.4    Bejar, R.5    Bodyak, N.6    Lee, K.H.7    Ma, Q.8    Kang, P.M.9    Golub, T.R.10
  • 115
    • 34748888492 scopus 로고    scopus 로고
    • Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure
    • Gupta, M.P. Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure. J. Mol. Cell. Cardiol. 2007, 43, 388-403.
    • (2007) J. Mol. Cell. Cardiol , vol.43 , pp. 388-403
    • Gupta, M.P.1
  • 117
    • 33646350032 scopus 로고    scopus 로고
    • Biophysical mechanisms of cardiac looping
    • Taber, L.A. Biophysical mechanisms of cardiac looping. Int. J. Dev. Biol. 2006, 50, 323-332.
    • (2006) Int. J. Dev. Biol. , vol.50 , pp. 323-332
    • Taber, L.A.1
  • 119
    • 80052596763 scopus 로고    scopus 로고
    • MicroRNA-23 restricts cardiac valve formation by inhibiting Has2 and extracellular hyaluronic acid production
    • Lagendijk, A.K.; Goumans, M.J.; Burkhard, S.B.; Bakkers J. MicroRNA-23 restricts cardiac valve formation by inhibiting Has2 and extracellular hyaluronic acid production. Circ. Res. 2011, 109, 649-657.
    • (2011) Circ. Res. , vol.109 , pp. 649-657
    • Lagendijk, A.K.1    Goumans, M.J.2    Burkhard, S.B.3    Bakkers, J.4
  • 121
    • 77957906102 scopus 로고    scopus 로고
    • VEGF signaling has distinct spatiotemporal roles during heart valve development
    • Stankunas, K.; Ma, G.K.; Kuhnert, F.J.; Kuo, C.J.; Chang, C.P. VEGF signaling has distinct spatiotemporal roles during heart valve development. Dev. Biol. 2010, 347, 325-336.
    • (2010) Dev. Biol. , vol.347 , pp. 325-336
    • Stankunas, K.1    Ma, G.K.2    Kuhnert, F.J.3    Kuo, C.J.4    Chang, C.P.5
  • 122
  • 123
    • 77951874053 scopus 로고    scopus 로고
    • NFATc4 is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophic repression
    • Li, Q.; Lin, X.; Yang, X.; Chang, J. NFATc4 is negatively regulated in miR-133a-mediated cardiomyocyte hypertrophic repression. Am. J. Physiol. Heart Circ. Physiol. 2010, 298, H1340-H1347.
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.298
    • Li, Q.1    Lin, X.2    Yang, X.3    Chang, J.4
  • 126
    • 79751513700 scopus 로고    scopus 로고
    • Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7
    • Yang, Y.; Ago, T.; Zhai, P.; Abdellatif, M.; Sadoshima, J. Thioredoxin 1 negatively regulates angiotensin II-induced cardiac hypertrophy through upregulation of miR-98/let-7. Circ. Res. 2011, 108, 305-313.
    • (2011) Circ. Res. , vol.108 , pp. 305-313
    • Yang, Y.1    Ago, T.2    Zhai, P.3    Abdellatif, M.4    Sadoshima, J.5
  • 127
    • 73449086958 scopus 로고    scopus 로고
    • Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions
    • Elia, L.; Contu, R.; Quintavalle, M.; Varrone, F.; Chimenti, C.; Russo, M.A.; Cimino, V.; de Marinis, L.; Frustaci, A.; Catalucci, D.; et al. Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation 2009, 120, 2377-2385.
    • (2009) Circulation , vol.120 , pp. 2377-2385
    • Elia, L.1    Contu, R.2    Quintavalle, M.3    Varrone, F.4    Chimenti, C.5    Russo, M.A.6    Cimino, V.7    de Marinis, L.8    Frustaci, A.9    Catalucci, D.10
  • 129
    • 77954895288 scopus 로고    scopus 로고
    • Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy
    • Li, Q.; Song, X.W.; Zou, J.; Wang, G.K.; Kremneva, E.; Li, X.Q.; Zhu, N.; Sun, T.; Lappalainen, P.; Yuan, W.J.; et al. Attenuation of microRNA-1 derepresses the cytoskeleton regulatory protein twinfilin-1 to provoke cardiac hypertrophy. J. Cell Sci. 2010, 123, 2444-2452.
    • (2010) J. Cell Sci , vol.123 , pp. 2444-2452
    • Li, Q.1    Song, X.W.2    Zou, J.3    Wang, G.K.4    Kremneva, E.5    Li, X.Q.6    Zhu, N.7    Sun, T.8    Lappalainen, P.9    Yuan, W.J.10
  • 130
    • 67649908891 scopus 로고    scopus 로고
    • MicroRNA-1 regulates cardiomyocyte apoptosis by targeting bcl-2
    • Tang, Y.; Zheng, J.; Sun, Y.; Wu, Z.; Liu, Z.; Huang, G. MicroRNA-1 regulates cardiomyocyte apoptosis by targeting bcl-2. Int. Heart J. 2009, 50, 377-387.
    • (2009) Int. Heart J. , vol.50 , pp. 377-387
    • Tang, Y.1    Zheng, J.2    Sun, Y.3    Wu, Z.4    Liu, Z.5    Huang, G.6
  • 131
    • 33847038668 scopus 로고    scopus 로고
    • MicroRNA play an essential role in development of cardiac hypertrophy
    • Sayed, D.; Hong, C.; Chen, I.Y.; Lypowy, J.; Abdellatif, M. MicroRNA play an essential role in development of cardiac hypertrophy. Circ. Res. 2007, 100, 416-424.
    • (2007) Circ. Res. , vol.100 , pp. 416-424
    • Sayed, D.1    Hong, C.2    Chen, I.Y.3    Lypowy, J.4    Abdellatif, M.5
  • 133
    • 77950463916 scopus 로고    scopus 로고
    • Reciprocal repression between microRNA-133 and calcineurin regulates cardiac hypertrophy: A novel mechanism for progressive cardiac hypertrophy
    • Dong, D.L.; Chen, C.; Huo, R.; Wang, N.; Li, Z.; Tu, Y.J.; Hu, J.T.; Chu, X.; Huang, W.; Yang, B.F. Reciprocal repression between microRNA-133 and calcineurin regulates cardiac hypertrophy: A novel mechanism for progressive cardiac hypertrophy. Hypertension 2010, 55, 946-952.
    • (2010) Hypertension , vol.55 , pp. 946-952
    • Dong, D.L.1    Chen, C.2    Huo, R.3    Wang, N.4    Li, Z.5    Tu, Y.J.6    Hu, J.T.7    Chu, X.8    Huang, W.9    Yang, B.F.10
  • 135
    • 74049096307 scopus 로고    scopus 로고
    • MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts
    • Matkovich, S.J.; Wang, W.; Tu, Y.; Eschenbacher, W.H.; Dorn, L.E.; Condorelli, G.; Diwan, A.; Nerbonne, J.M.; Dorn, G.W., 2nd. MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts. Circ. Res. 2010, 106, 166-175.
    • (2010) Circ. Res. , vol.106 , pp. 166-175
    • Matkovich, S.J.1    Wang, W.2    Tu, Y.3    Eschenbacher, W.H.4    Dorn, L.E.5    Condorelli, G.6    Diwan, A.7    Nerbonne, J.M.8    Dorn II, G.W.9
  • 137
    • 77951245829 scopus 로고    scopus 로고
    • miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy
    • Wang, K.; Long, B.; Zhou, J.; Li, P.F. miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy. J. Biol. Chem. 2010, 285, 11903-11912.
    • (2010) J. Biol. Chem. , vol.285 , pp. 11903-11912
    • Wang, K.1    Long, B.2    Zhou, J.3    Li, P.F.4
  • 138
    • 67749106564 scopus 로고    scopus 로고
    • miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy
    • Lin, Z.; Murtaza, I.; Wang, K.; Jiao, J.; Gao, J.; Li, P.F. miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 2009, 106, 12103-12108.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 12103-12108
    • Lin, Z.1    Murtaza, I.2    Wang, K.3    Jiao, J.4    Gao, J.5    Li, P.F.6
  • 140
    • 34247589595 scopus 로고    scopus 로고
    • Control of stress-dependent cardiac growth and gene expression by a microRNA
    • Van Rooij, E.; Sutherland, L.B.; Qi, X.; Richardson, J.A.; Hill, J.; Olson, E.N. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science 2007, 316, 575-579.
    • (2007) Science , vol.316 , pp. 575-579
    • Van Rooij, E.1    Sutherland, L.B.2    Qi, X.3    Richardson, J.A.4    Hill, J.5    Olson, E.N.6
  • 142
    • 79955800181 scopus 로고    scopus 로고
    • Elevated miR-499 levels blunt the cardiac stress response
    • Shieh, J.T.; Huang, Y.; Gilmore, J.; Srivastava, D. Elevated miR-499 levels blunt the cardiac stress response. PLoS One 2011, 6, e19481.
    • (2011) PLoS One , vol.6
    • Shieh, J.T.1    Huang, Y.2    Gilmore, J.3    Srivastava, D.4
  • 145
    • 34250770436 scopus 로고    scopus 로고
    • Transforming growth factor-beta and microRNA:MRNA regulatory networks in epithelial plasticity
    • Zavadil, J.; Narasimhan, M.; Blumenberg, M.; Schneider, R.J. Transforming growth factor-beta and microRNA:mRNA regulatory networks in epithelial plasticity. Cells Tissues Organs 2007, 185, 157-161.
    • (2007) Cells Tissues Organs , vol.185 , pp. 157-161
    • Zavadil, J.1    Narasimhan, M.2    Blumenberg, M.3    Schneider, R.J.4
  • 146
    • 62349141343 scopus 로고    scopus 로고
    • MicroRNA expression in response to murine myocardial infarction: MiR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue
    • Roy, S.; Khanna, S.; Hussain, S.R.; Biswas, S.; Azad, A.; Rink, C.; Gnyawali, S.; Shilo, S.; Nuovo, G.J.; Sen, C.K. MicroRNA expression in response to murine myocardial infarction: miR-21 regulates fibroblast metalloprotease-2 via phosphatase and tensin homologue. Cardiovasc. Res. 2009, 82, 21-29.
    • (2009) Cardiovasc. Res. , vol.82 , pp. 21-29
    • Roy, S.1    Khanna, S.2    Hussain, S.R.3    Biswas, S.4    Azad, A.5    Rink, C.6    Gnyawali, S.7    Shilo, S.8    Nuovo, G.J.9    Sen, C.K.10
  • 148
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin I (TPM1)
    • Zhu, S.M.; Si, M.L.; Wu, H.L.; Mo, Y.Y. MicroRNA-21 targets the tumor suppressor gene tropomyosin I (TPM1). J. Biol. Chem. 2007, 282, 14328-14336.
    • (2007) J. Biol. Chem. , vol.282 , pp. 14328-14336
    • Zhu, S.M.1    Si, M.L.2    Wu, H.L.3    Mo, Y.Y.4
  • 150
    • 55449100829 scopus 로고    scopus 로고
    • Toward microRNA-based therapeutics for heart disease: The sense in antisense
    • Van Rooij, E.; Marshall, W.S.; Olson, E.N. Toward microRNA-based therapeutics for heart disease: The sense in antisense. Circ. Res. 2008, 103, 919-928.
    • (2008) Circ. Res. , vol.103 , pp. 919-928
    • Van Rooij, E.1    Marshall, W.S.2    Olson, E.N.3
  • 151
    • 84868705910 scopus 로고    scopus 로고
    • Long noncoding RNAs in cardiac development and pathophysiology
    • Schonrock, N.; Harvey, R.P.; Mattick, J.S. Long noncoding RNAs in cardiac development and pathophysiology. Circ. Res. 2012, 111, 1349-1362.
    • (2012) Circ. Res. , vol.111 , pp. 1349-1362
    • Schonrock, N.1    Harvey, R.P.2    Mattick, J.S.3
  • 157
    • 12844269788 scopus 로고    scopus 로고
    • Role of endogenous antisense RNA in cardiac gene regulation
    • Luther, H.P. Role of endogenous antisense RNA in cardiac gene regulation. J. Mol. Med. 2005, 83, 26-32.
    • (2005) J. Mol. Med , vol.83 , pp. 26-32
    • Luther, H.P.1


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