Wheat germ agglutinin-functionalised crosslinked polyelectrolyte microparticles for local colon delivery of 5-FU: In vitro efficacy and in vivo gastrointestinal distribution

Journal of Microencapsulation

Volumn 30, Issue 7, 2013, Pages 643-656

  Glavas Dodov, Marija ^a   Steffansen, Bente ^b   Crcarevska, Maja S ^a   Geskovski, Nikola ^a   Dimchevska, Simona ^a   Kuzmanovska, Sonja ^c   Goracinova, Katerina ^a  

^a SS Cyril and Methodius University Faculty of Pharmacy   (Macedonia)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c SS CYRIL AND METHODIUS UNIVERSITY OF SKOPJE   (Macedonia)

Author keywords

5 fluorouracil; Caco 2; Gastrointestinal distribution; Hydrogel microparticles; Wheat germ agglutinin

Indexed keywords

ALGINIC ACID; CALCIUM ALGINATE; CHITOSAN; DRUG CARRIER; FLUOROURACIL; HYDROXYPROPYLMETHYLCELLULOSE; HYDROXYPROPYLMETHYLCELLULOSE PHTHALATE; POLYELECTROLYTE; WHEAT GERM AGGLUTININ;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN CACO 2; COLON CANCER; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG PENETRATION; DRUG UPTAKE; GASTROINTESTINAL TRACT; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; RAT;

ALGINATES; ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CACO-2 CELLS; CHITOSAN; COLON; COLONIC NEOPLASMS; DRUG CARRIERS; FLUOROURACIL; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; MALE; RATS; RATS, WISTAR; TRITICUM; WHEAT GERM AGGLUTININS;

EID: 84885357366     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.3109/02652048.2013.770099     Document Type: Article

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