(Z)-4-Bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one sensitizes Escherichia coli persister cells to antibiotics

Applied Microbiology and Biotechnology

Volumn 97, Issue 20, 2013, Pages 9145-9154

  Pan, Jiachuan ^a,b   Xie, Xin ^c,d   Tian, Wang ^c   Bahar, Ali Adem ^a,b   Lin, Nan ^c   Song, Fangchao ^a,b   An, Jing ^c   Ren, Dacheng ^a,b  

^a Syracuse University   (United States)

^b SYRACUSE UNIVERSITY   (United States)

^c SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

^d LIAONING UNIVERSITY   (China)

Author keywords

Antibiotic tolerance; Biofilm; Inhibition; Persister; Quorum sensing

Indexed keywords

ANTIBIOTIC TOLERANCES; BACTERIAL CELLS; DRUG RESISTANCE GENES; ESCHERICHIA COLI GROWTHS; MAMMALIAN CELLS; MULTIDRUG RESISTANCE; PERSISTER; QUORUM-SENSING;

BIOFILMS; CELLS; CYTOLOGY; ENZYME INHIBITION; ESCHERICHIA COLI;

ANTIBIOTICS;

4 BROMO 5 (BROMOMETHYLENE) 3 METHYLFURAN 2(5H) ONE; AMPICILLIN; ANTIBIOTIC AGENT; FURANONE DERIVATIVE; GENTAMICIN; OFLOXACIN; TETRACYCLINE; TOBRAMYCIN; UNCLASSIFIED DRUG;

ANTIBIOTICS; BACTERIUM; BIOFILM; DRUG RESISTANCE; GROWTH; PERSISTENCE; PH; SUBPOPULATION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL GROWTH; BACTERIAL PERSISTER CELL; BACTERIUM MUTANT; BIOFILM; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISPERSION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; DRUG SAFETY; DRUG SENSITIZATION; DRUG TOLERABILITY; DRUG TOLERANCE; ESCHERICHIA COLI; IN VITRO STUDY; IN VIVO STUDY; MAMMAL CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PH; QUORUM SENSING; WILD TYPE;

3T3 CELLS; 4-BUTYROLACTONE; ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CELL LINE; CELL SURVIVAL; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; HUMANS; MICE; MICE, INBRED C57BL; MICROBIAL SENSITIVITY TESTS; QUORUM SENSING;

EID: 84885337535     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5185-2     Document Type: Article

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