In vitro efficacy of approved and experimental antivirals against novel genotype 3 hepatitis C virus subgenomic replicons

Antiviral Research

Volumn 100, Issue 2, 2013, Pages 439-445

  Yu, Mei ^a   Corsa, Amoreena C ^a   Xu, Simin ^a   Peng, Betty ^a   Gong, Ruoyu ^a   Lee, Yu Jen ^a   Chan, Katie ^a   Mo, Hongmei ^a   Delaney IV, William ^a   Cheng, Guofeng ^a  

^a Gilead Sciences   (United States)

Author keywords

Direct acting antivirals; Genotype 3 HCV; Huh 7 1C cells; P89L mutation in NS3; Pan genotype

Indexed keywords

ANTIVIRUS AGENT; BOCEPREVIR; CILUPREVIR; CYCLOPHILIN A; DACLATASVIR; FILIBUVIR; GS 9669; MK 3281; MK 5172; NESBUVIR; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4; SOFOSBUVIR; TEGOBUVIR; TELAPREVIR; UNCLASSIFIED DRUG; VEDROPREVIR; VIRUS RNA; ANTIBIOTIC G 418; CYCLOSPORIN A; LUCIFERASE; RENILLA LUCIFERIN 2 MONOOXYGENASE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; GENOTYPE; HEPATITIS C VIRUS; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; REPLICON; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA REPLICATION; 2-C-METHYL ADENOSINE; 2-CMEA; 50% EFFECTIVE INHIBITORY CONCENTRATION; CELL LINE; CLASSIFICATION; CSA; DAA; DIRECT-ACTING ANTIVIRALS; DRUG EFFECT; EC(50); GENETICS; GENOTYPE 3 HCV; GT; HCV; HEPATIC C VIRUS; HUH-7 1C CELLS; HUMAN; LIVER CELL; METHODOLOGY; MICROBIAL SENSITIVITY TEST; NEO; NEOMYCIN TRANSFERASE GENE; NON-STRUCTURAL; NS; P89L MUTATION IN NS3; PAN-GENOTYPE; RELATIVE LIGHT UNITS; REPORTER GENE; RLU; RLUC; VIROLOGY; VIRUS REPLICATION;

HEPATITIS C VIRUS;

2-C-METHYL ADENOSINE; 2-CMEA; 50% EFFECTIVE INHIBITORY CONCENTRATION; CSA; CYCLOSPORIN A; DAA; DIRECT-ACTING ANTIVIRALS; EC(50); G418; GENETICIN; GENOTYPE; GENOTYPE 3 HCV; GT; HCV; HEPATIC C VIRUS; HUH-7 1C CELLS; NEO; NEOMYCIN TRANSFERASE GENE; NON-STRUCTURAL; NS; P89L MUTATION IN NS3; PAN-GENOTYPE; RELATIVE LIGHT UNITS; RENILLA LUCIFERASE; RLU; RLUC;

ANTIVIRAL AGENTS; CELL LINE; GENES, REPORTER; GENOTYPE; HEPACIVIRUS; HEPATOCYTES; HUMANS; LUCIFERASES; MICROBIAL SENSITIVITY TESTS; REPLICON; VIRUS REPLICATION;

EID: 84885334074     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2013.08.018     Document Type: Article

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