Cyclooxygenase-2 promotes hepatocellular apoptosis by interacting with TNF-α and IL-6 in the pathogenesis of nonalcoholic steatohepatitis in rats

Digestive Diseases and Sciences

Volumn 58, Issue 10, 2013, Pages 2895-2902

  Cheng, Qi ^a   Li, Ning ^a   Chen, Mingquan ^a   Zheng, Jianming ^a   Qian, Zhiping ^b   Wang, Xinyu ^a   Huang, Chong ^a   Xu, Shuchang ^c   Shi, Guangfeng ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

^c TONGJI UNIVERSITY   (China)

Author keywords

Apoptosis; COX 2; IL 6; Inflammation; Nonalcoholic steatohepatitis; TNF

Indexed keywords

CELECOXIB; CYCLOOXYGENASE 2; EOSIN; HEMATOXYLIN; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; DISEASE SEVERITY; ELECTRON MICROSCOPY; GENE EXPRESSION; INFLAMMATION; LIVER CELL; MALE; MEDIATOR RELEASE; NICK END LABELING; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; APOPTOSIS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; FATTY LIVER; HEPATOCYTES; INTERLEUKIN-6; LIVER; MALE; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; SEVERITY OF ILLNESS INDEX; SULFONAMIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84885321773     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-013-2823-6     Document Type: Article

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