Editorial: Challenging ticagrelor's claimed reduction in the rate of definite stent thrombosis versus clopidogrel: Insights from the FDA reports

International Journal of Cardiology

Volumn 168, Issue 2, 2013, Pages 633-635

  Di Nicolantonio, James J ^a   Biondi Zoccai, Giuseppe ^b  

^a Wegmans Pharmacy   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Acute coronary syndrome; Clopidogrel; Stent thrombosis; Ticagrelor

Indexed keywords

ADENOSINE; CLOPIDOGREL; DRUG DERIVATIVE; TICAGRELOR; TICLOPIDINE;

ACUTE CORONARY SYNDROME; COMPARATIVE STUDY; DRUG ELUTING STENT; EDITORIAL; FOOD AND DRUG ADMINISTRATION; HUMAN; RANDOMIZED CONTROLLED TRIAL (TOPIC); STENT THROMBOSIS; THROMBOSIS; UNITED STATES;

ACUTE CORONARY SYNDROME; CLOPIDOGREL; STENT THROMBOSIS; TICAGRELOR;

ADENOSINE; DRUG-ELUTING STENTS; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; THROMBOSIS; TICLOPIDINE; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 84885313186     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2013.04.149     Document Type: Editorial

References (8)

1. Wallentin L, Becker RC, Budaj A, et al. Ticagrelor versus clopidogrel In patients with acute coronary syndromes. N Engl J Med 2009;361:1045-57.
2. http://www1.astrazeneca-us.com/pi/brilInta.pdf.
3. http://www.accessdata.fda.gov/drugsatfda-docs/nda/2011/ 022433Orig1s000Lbl.pdf.
4. https://www.brilIntatouchpoInts.com/stent-thrombosis/.
5. U.S. Food and Drug Administration. Drug approval package: BrilInta (tricagrelor) tablets. Available from http://www.accessdata.fda.gov/drugsatfda- docs/nda/2011/022433Orig1s000TOC.cfm; Feb. 9 2013 . [Accessed].
6. Serebruany VL, DiNicolantonio JJ, Can MM. Mortality In the TRACER and ATLAS ACS 2 trials: two more reasons to audit vital records In PLATO. Cardiology 2012;123: 11-4.
7. DiNicolantonio JJ, Can MM, Serebruany VL. Lost In follow-up rates In TRACER, ATLAS ACS 2, TRiTON and TRA 2P trials: challenging PLATO mortality rates. Int J Cardiol 2013;164:255-8.
8. DiNicolantonio JJ, Serebruany VL. Exploring the reduction In myocardial Infarction In the PLATO trial: which patients benefited on ticagrelor vs. clopidogrel? Int J Cardio 2013;165:396-7.