Angiotensin receptor blockade has protective effects on the poststenotic porcine kidney

Kidney International

Volumn 84, Issue 4, 2013, Pages 767-775

  Zhang, Xin ^a   Eirin, Alfonso ^a   Li, Zi Lun ^a,b   Crane, John A ^a   Krier, James D ^a   Ebrahimi, Behzad ^a   Pawar, Aditya S ^a   Zhu, Xiang Yang ^a   Tang, Hui ^a   Jordan, Kyra L ^a   Lerman, Amir ^a   Textor, Stephen C ^a   Lerman, Lilach O ^a  

^a MAYO CLINIC   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

angiotensin II type I receptor blockade; microvasculature; renal artery stenosis

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN RECEPTOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBROBLAST GROWTH FACTOR 2; HYDRALAZINE PLUS HYDROCHLOROTHIAZIDE PLUS RESERPINE; THROMBOSPONDIN 1; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; VALSARTAN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE MEASUREMENT; CONTROLLED STUDY; DOMESTIC PIG; FEMALE; GLOMERULUS FILTRATION RATE; KIDNEY ARTERY STENOSIS; KIDNEY BLOOD FLOW; KIDNEY PERFUSION; KIDNEY TUBULE FUNCTION; LONG TERM CARE; MICROCIRCULATION; MULTIDETECTOR COMPUTED TOMOGRAPHY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; OXYGEN BLOOD LEVEL; OXYGENATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RENAL PROTECTION;

ACUTE KIDNEY INJURY; ANGIOTENSIN RECEPTOR ANTAGONISTS; ANIMALS; CONSTRICTION, PATHOLOGIC; DISEASE MODELS, ANIMAL; FEMALE; GLOMERULAR FILTRATION RATE; HEMODYNAMICS; KIDNEY; MICROCIRCULATION; OXIDATIVE STRESS; RECEPTORS, ANGIOTENSIN; RENAL ARTERY OBSTRUCTION; SWINE; TETRAZOLES; VALINE;

EID: 84885294216     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.144     Document Type: Article

References (40)

1. Colyer WR Jr., Cooper CJ. Cardiovascular morbidity and mortality and renal artery stenosis. Prog Cardiovasc Dis 2009; 52: 238-242.
2. Yusuf S, Sleight P, Pogue J et al. Effects of an angiotensin- convertingenzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 2000; 342: 145-153.
3. Yusuf S, Teo KK, Pogue J et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med 2008; 358: 1547-1559.
4. Dworkin LD. Controversial treatment of atherosclerotic renal vascular disease: the cardiovascular outcomes in renal atherosclerotic lesions trial. Hypertension 2006; 48: 350-356.
5. Onuigbo MA, Onuigbo NT. Worsening renal failure in older chronic kidney disease patients with renal artery stenosis concurrently on renin angiotensin aldosterone system blockade: a prospective 50-month Mayo-Health-System clinic analysis. QJM 2008; 101: 519-527.
6. Chrysochou C, Foley RN, Young JF et al. Dispelling the myth: the use of renin-angiotensin blockade in atheromatous renovascular disease. Nephrol Dial Transplant 2012; 27: 1403-1409.
7. Zhu XY, Chade AR, Rodriguez-Porcel M et al. Cortical microvascular remodeling in the stenotic kidney: role of increased oxidative stress. Arterioscler Thromb Vasc Biol 2004; 24: 1854-1859.
8. Chade AR, Zhu X, Mushin OP et al. Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia. FASEB J 2006; 20: 1706-1708.
9. Onozato ML, Tojo A, Goto A et al. Oxidative stress and nitric oxide synthase in rat diabetic nephropathy: effects of ACEI and ARB. Kidney Int 2002; 61: 186-194.
10. Esteban V, Lorenzo O, Ruperez M et al. Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. J Am Soc Nephrol 2004; 15: 1514-1529.
11. Warner L, Glockner JF, Woollard J et al. Determinations of renal cortical and medullary oxygenation using blood oxygen level-dependent magnetic resonance imaging and selective diuretics. Invest Radiol 2011; 46: 41-47.
12. Ebrahimi B, Gloviczki M, Woollard JR et al. Compartmental analysis of renal BOLD MRI data: introduction and validation. Invest Radiol 2012; 47: 175-182.
13. Yuan HT, Suri C, Yancopoulos GD et al. Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation. J Am Soc Nephrol 1999; 10: 1722-1736.
14. Chade AR, Zhu X, Lavi R et al. Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation 2009; 119: 547-557.
15. Lerman LO, Textor SC, Grande JP. Mechanisms of tissue injury in renal artery stenosis: ischemia and beyond. Prog Cardiovasc Dis 2009; 52: 196-203.
16. Favreau F, Zhu XY, Krier JD et al. Revascularization of swine renal artery stenosis improves renal function but not the changes in vascular structure. Kidney Int 2010; 78: 1110-1118.
17. Chade AR, Kelsen S. Reversal of renal dysfunction by targeted administration of VEGF into the stenotic kidney: a novel potential therapeutic approach. Am J Physiol Renal Physiol 2012; 302: F1342-F1350.
18. Ruiz-Ortega M, Ruperez M, Lorenzo O et al. Angiotensin II regulates the synthesis of proinflammatory cytokines and chemokines in the kidney. Kidney Int Suppl 2002; 82: S12-S22.
19. Eirin A, Zhu XY, Urbieta-Caceres VH et al. Persistent kidney dysfunction in swine renal artery stenosis correlates with outer cortical microvascular remodeling. Am J Physiol Renal Physiol 2011; 300: F1394-F1401.
20. Echols MR, Yancy CW. Isosorbide dinitrate-hydralazine combination therapy in African Americans with heart failure. Vasc Health Risk Manag 2006; 2: 423-431.
21. Xu B, Thornton C, Makris A et al. Anti-hypertensive drugs alter cytokine production from preeclamptic placentas and peripheral blood mononuclear cells. Hypertens Pregnancy 2007; 26: 343-356.
22. Komatsu K, Numabe A, Ono Y et al. Hydrochlorothiazide increases efferent glomerular arteriolar resistance in spontaneously hypertensive rats. J Cardiovasc Pharmacol Ther 1996; 1: 57-64.
23. Velasquez MT, Striffler JS, Abraham AA et al. Perindopril ameliorates glomerular and renal tubulointerstitial injury in the SHR/N-corpulent rat. Hypertension 1997; 30: 1232-1237.
24. Gloviczki ML, Glockner JF, Crane JA et al. Blood oxygen level-dependent magnetic resonance imaging identifies cortical hypoxia in severe renovascular disease. Hypertension 2011; 58: 1066-1072.
25. Gloviczki ML, Glockner JF, Lerman LO et al. Preserved oxygenation despite reduced blood flow in poststenotic kidneys in human atherosclerotic renal artery stenosis. Hypertension 2010; 55: 961-966.
26. Ebrahimi B, Li Z, Eirin A et al. Addition of endothelial progenitor cells to renal revascularization restores medullary tubular oxygen consumption in swine renal artery stenosis. Am J Physiol Renal Physiol 2012; 302: F1478-F1485.
27. Wolf G, Ritz E. Combination therapy with ACE inhibitors and angiotensin II receptor blockers to halt progression of chronic renal disease: pathophysiology and indications. Kidney Int 2005; 67: 799-812.
28. Matavelli LC, Huang J, Siragy HM. Angiotensin AT(2) receptor stimulation inhibits early renal inflammation in renovascular hypertension. Hypertension 2011; 57: 308-313.
29. Rizkalla B, Forbes JM, Cooper ME et al. Increased renal vascular endothelial growth factor and angiopoietins by angiotensin II infusion is mediated by both AT1 and AT2 receptors. J Am Soc Nephrol 2003; 14: 3061-3071.
30. Willis LM, El-Remessy AB, Somanath PR et al. Angiotensin receptor blockers and angiogenesis: clinical and experimental evidence. Clin Sci (Lond) 2011; 120: 307-319.
31. Gallinat S, Busche S, Raizada MK et al. The angiotensin II type 2 receptor: an enigma with multiple variations. Am J Physiol Endocrinol Metab 2000; 278: E357-E374.
32. Ozono R, Wang ZQ, Moore AF et al. Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney. Hypertension 1997; 30: 1238-1246.
33. Munzenmaier DH, Greene AS. Chronic angiotensin II AT1 receptor blockade increases cerebral cortical microvessel density. Am J Physiol Heart Circ Physiol 2006; 290: H512-H516.
34. Chade AR, Rodriguez-Porcel M, Grande JP et al. Distinct renal injury in early atherosclerosis and renovascular disease. Circulation 2002; 106: 1165-1171.
35. Zhu XY, Rodriguez-Porcel M, Bentley MD et al. Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia. Circulation 2004; 109: 2109-2115.
36. Zhu XY, Daghini E, Chade AR et al. Simvastatin prevents coronary microvascular remodeling in renovascular hypertensive pigs. J Am Soc Nephrol 2007; 18: 1209-1217.
37. Chatzizisis YS, Jonas M, Beigel R et al. Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques. Atherosclerosis 2009; 203: 387-394.
38. Randsbaek F, Lund S, Kimose HH et al. Angiotensin II inhibition increases cellular glucose transport during reperfusion but not ischemia in pig hearts. Scand Cardiovasc J 2003; 37: 205-210.
39. Daghini E, Primak AN, Chade AR et al. Assessment of renal hemodynamics and function in pigs with 64-section multidetector CT: comparison with electron-beam CT. Radiology 2007; 243: 405-412.
40. Eirin A, Gloviczki ML, Tang H et al. Chronic renovascular hypertension is associated with elevated levels of neutrophil gelatinase-associated lipocalin. Nephrol Dial Transplant 2012; 27: 4153-4161.