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Volumn 29, Issue 5, 2013, Pages 642-648

Structural changes in the gray matter of unmedicated patients with obsessive-compulsive disorder: A voxel-based morphometric study

Author keywords

gray matter; magnetic resonance imaging; obsessive compulsive disorder; voxel based morphometry

Indexed keywords

ADULT; ARTICLE; BRAIN SIZE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GLOBUS PALLIDUS; GRAY MATTER; HUMAN; MALE; MIDDLE TEMPORAL GYRUS; MORPHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OBSESSIVE COMPULSIVE DISORDER; OCCIPITAL GYRUS; PARAHIPPOCAMPAL GYRUS; PARIETAL GYRUS; PARS OPERCULARIS; SUPERIOR FRONTAL GYRUS; SUPRAMARGINAL GYRUS; VOXEL BASED MORPHOMETRY;

EID: 84885292818     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-013-1370-7     Document Type: Article
Times cited : (30)

References (40)
  • 2
    • 0026514476 scopus 로고
    • The epidemiology and differential diagnosis of obsessive compulsive disorder
    • 1564054
    • Rasmussen SA, Eisen JL. The epidemiology and differential diagnosis of obsessive compulsive disorder. J Clin Psychiatry 1992, 53Suppl: 4-10.
    • (1992) J Clin Psychiatry , vol.53 , Issue.SUPPL. , pp. 4-10
    • Rasmussen, S.A.1    Eisen, J.L.2
  • 4
    • 0036426996 scopus 로고    scopus 로고
    • Structural gray matter differences between first-episode schizophrenics and normal controls using voxelbased morphometry
    • 12377162 10.1006/nimg.2002.1180
    • Job DE, Whalley HC, McConnell S, Glabus M, Johnstone EC, Lawrie SM. Structural gray matter differences between first-episode schizophrenics and normal controls using voxelbased morphometry. Neuroimage 2002, 17: 880-889.
    • (2002) Neuroimage , vol.17 , pp. 880-889
    • Job, D.E.1    Whalley, H.C.2    McConnell, S.3    Glabus, M.4    Johnstone, E.C.5    Lawrie, S.M.6
  • 5
    • 77956627406 scopus 로고    scopus 로고
    • Clinical and anatomical heterogeneity in autistic spectrum disorder: A structural MRI study
    • 19891805 10.1017/S0033291709991541 1:STN:280:DC%2BC3cvhtlOjtQ%3D%3D
    • Toal F, Daly EM, Page L, Deeley Q, Hallahan B, Bloemen O, et al. Clinical and anatomical heterogeneity in autistic spectrum disorder: a structural MRI study. Psychol Med 2010, 40: 1171-1181.
    • (2010) Psychol Med , vol.40 , pp. 1171-1181
    • Toal, F.1    Daly, E.M.2    Page, L.3    Deeley, Q.4    Hallahan, B.5    Bloemen, O.6
  • 6
    • 29144481596 scopus 로고    scopus 로고
    • Neuroimaging studies of obsessive-compulsive disorder in adults and children
    • 16242823 10.1016/j.cpr.2005.06.010
    • Friedlander L, Desrocher M. Neuroimaging studies of obsessive-compulsive disorder in adults and children. Clin Psychol Rev 2006, 26: 32-49.
    • (2006) Clin Psychol Rev , vol.26 , pp. 32-49
    • Friedlander, L.1    Desrocher, M.2
  • 7
    • 0037365859 scopus 로고    scopus 로고
    • Differential brain metabolic predictors of response to paroxetine in obsessive-compulsive disorder versus major depression
    • 12611834 10.1176/appi.ajp.160.3.522
    • Saxena S, Brody AL, Ho ML, Zohrabi N, Maidment KM, Baxter LR Jr. Differential brain metabolic predictors of response to paroxetine in obsessive-compulsive disorder versus major depression. Am J Psychiatry 2003, 160: 522-532.
    • (2003) Am J Psychiatry , vol.160 , pp. 522-532
    • Saxena, S.1    Brody, A.L.2    Ho, M.L.3    Zohrabi, N.4    Maidment, K.M.5    Baxter, Jr.L.R.6
  • 8
    • 2942560512 scopus 로고    scopus 로고
    • Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessivecompulsive disorder
    • 15169693 10.1176/appi.ajp.161.6.1049
    • Szeszko PR, MacMillan S, McMeniman M, Chen S, Baribault K, Lim KO, et al. Brain structural abnormalities in psychotropic drug-naive pediatric patients with obsessivecompulsive disorder. Am J Psychiatry 2004, 161: 1049-1056.
    • (2004) Am J Psychiatry , vol.161 , pp. 1049-1056
    • Szeszko, P.R.1    Macmillan, S.2    McMeniman, M.3    Chen, S.4    Baribault, K.5    Lim, K.O.6
  • 9
    • 25844478536 scopus 로고    scopus 로고
    • Regional gray matter abnormalities in obsessive-compulsive disorder: A voxel-based morphometry study
    • 15978549 10.1016/j.biopsych.2005.04.021
    • Valente AA Jr, Miguel EC, Castro CC, Amaro E Jr, Duran FL, Buchpiguel CA, et al. Regional gray matter abnormalities in obsessive-compulsive disorder: a voxel-based morphometry study. Biol Psychiatry 2005, 58: 479-487.
    • (2005) Biol Psychiatry , vol.58 , pp. 479-487
    • Valente, Jr.A.A.1    Miguel, E.C.2    Castro, C.C.3    Amaro, Jr.E.4    Duran, F.L.5    Buchpiguel, C.A.6
  • 10
    • 41149160098 scopus 로고    scopus 로고
    • Gray matter differences between pediatric obsessive-compulsive disorder patients and highrisk siblings: A preliminary voxel-based morphometry study
    • 18314272 10.1016/j.neulet.2008.02.011 1:CAS:528:DC%2BD1cXktVCksbk%3D
    • Gilbert AR, Keshavan MS, Diwadkar V, Nutche J, Macmaster F, Easter PC, et al. Gray matter differences between pediatric obsessive-compulsive disorder patients and highrisk siblings: a preliminary voxel-based morphometry study. Neurosci Lett 2008, 435: 45-50.
    • (2008) Neurosci Lett , vol.435 , pp. 45-50
    • Gilbert, A.R.1    Keshavan, M.S.2    Diwadkar, V.3    Nutche, J.4    Macmaster, F.5    Easter, P.C.6
  • 11
    • 53549125323 scopus 로고    scopus 로고
    • Gray matter structural alterations in obsessive-compulsive disorder: Relationship to neuropsychological functions
    • 18938065 10.1016/j.pscychresns.2008.03.005
    • Christian CJ, Lencz T, Robinson DG, Burdick KE, Ashtari M, Malhotra AK, et al. Gray matter structural alterations in obsessive-compulsive disorder: relationship to neuropsychological functions. Psychiatry Res 2008, 164: 123-131.
    • (2008) Psychiatry Res , vol.164 , pp. 123-131
    • Christian, C.J.1    Lencz, T.2    Robinson, D.G.3    Burdick, K.E.4    Ashtari, M.5    Malhotra, A.K.6
  • 12
    • 40549102436 scopus 로고    scopus 로고
    • Voxel-based morphometry study of gray matter abnormalities in obsessive-compulsive disorder
    • 18303194 10.3346/jkms.2008.23.1.24
    • Yoo SY, Roh MS, Choi JS, Kang DH, Ha TH, Lee JM, et al. Voxel-based morphometry study of gray matter abnormalities in obsessive-compulsive disorder. J Korean Med Sci 2008, 23: 24-30.
    • (2008) J Korean Med Sci , vol.23 , pp. 24-30
    • Yoo, S.Y.1    Roh, M.S.2    Choi, J.S.3    Kang, D.H.4    Ha, T.H.5    Lee, J.M.6
  • 14
    • 20444501009 scopus 로고    scopus 로고
    • Unified segmentation
    • 15955494 10.1016/j.neuroimage.2005.02.018
    • Ashburner J, Friston KJ. Unified segmentation. Neuroimage 2005, 26: 839-851.
    • (2005) Neuroimage , vol.26 , pp. 839-851
    • Ashburner, J.1    Friston, K.J.2
  • 15
    • 0034781637 scopus 로고    scopus 로고
    • Grey matter abnormalities in obsessive-compulsive disorder: Statistical parametric mapping of segmented magnetic resonance images
    • 11581113 10.1192/bjp.179.4.330 1:STN:280:DC%2BD3Mrnt1GjtQ%3D%3D
    • Kim JJ, Lee MC, Kim J, Kim IY, Kim SI, Han MH, et al. Grey matter abnormalities in obsessive-compulsive disorder: statistical parametric mapping of segmented magnetic resonance images. Br J Psychiatry 2001, 179: 330-334.
    • (2001) Br J Psychiatry , vol.179 , pp. 330-334
    • Kim, J.J.1    Lee, M.C.2    Kim, J.3    Kim, I.Y.4    Kim, S.I.5    Han, M.H.6
  • 16
    • 60549114222 scopus 로고    scopus 로고
    • Neuroimaging in obsessive-compulsive disorder
    • 19210199 10.1586/14737175.9.2.255
    • Kwon JS, Jang JH, Choi JS, Kang DH. Neuroimaging in obsessive-compulsive disorder. Expert Rev Neurother 2009, 9: 255-269.
    • (2009) Expert Rev Neurother , vol.9 , pp. 255-269
    • Kwon, J.S.1    Jang, J.H.2    Choi, J.S.3    Kang, D.H.4
  • 17
    • 65249136462 scopus 로고    scopus 로고
    • The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems
    • 18952675 10.1093/brain/awn267
    • van den Heuvel OA, Remijnse PL, Mataix-Cols D, Vrenken H, Groenewegen HJ, Uylings HB, et al. The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems. Brain 2009, 132: 853-868.
    • (2009) Brain , vol.132 , pp. 853-868
    • Van Den Heuvel, O.A.1    Remijnse, P.L.2    Mataix-Cols, D.3    Vrenken, H.4    Groenewegen, H.J.5    Uylings, H.B.6
  • 18
    • 75749095926 scopus 로고    scopus 로고
    • Gray matter alterations in obsessive-compulsive disorder: An anatomic likelihood estimation meta-analysis
    • 19890260 10.1038/npp.2009.175 1:CAS:528:DC%2BC3cXhtlCrurk%3D
    • Rotge JY, Langbour N, Guehl D, Bioulac B, Jaafari N, Allard M, et al. Gray matter alterations in obsessive-compulsive disorder: an anatomic likelihood estimation meta-analysis. Neuropsychopharmacology 2010, 35: 686-691.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 686-691
    • Rotge, J.Y.1    Langbour, N.2    Guehl, D.3    Bioulac, B.4    Jaafari, N.5    Allard, M.6
  • 19
    • 2942564586 scopus 로고    scopus 로고
    • Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder
    • 15184236 10.1001/archpsyc.61.6.564
    • Mataix-Cols D, Wooderson S, Lawrence N, Brammer MJ, Speckens A, Phillips ML. Distinct neural correlates of washing, checking, and hoarding symptom dimensions in obsessive-compulsive disorder. Arch Gen Psychiatry 2004, 61: 564-576.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 564-576
    • Mataix-Cols, D.1    Wooderson, S.2    Lawrence, N.3    Brammer, M.J.4    Speckens, A.5    Phillips, M.L.6
  • 20
    • 77955863442 scopus 로고    scopus 로고
    • Basal ganglia MR relaxometry in obsessivecompulsive disorder: T2 depends upon age of symptom onset
    • 20503112 10.1007/s11682-009-9083-2
    • Correia S, Hubbard E, Hassenstab J, Yip A, Vymazal J, Herynek V, et al. Basal ganglia MR relaxometry in obsessivecompulsive disorder: T2 depends upon age of symptom onset. Brain Imaging Behav 2010, 4: 35-45.
    • (2010) Brain Imaging Behav , vol.4 , pp. 35-45
    • Correia, S.1    Hubbard, E.2    Hassenstab, J.3    Yip, A.4    Vymazal, J.5    Herynek, V.6
  • 21
    • 34547799764 scopus 로고    scopus 로고
    • Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder
    • 17679639 10.1001/archpsyc.64.8.946 1:CAS:528:DC%2BD2sXhtVWhsLvP
    • Yucel M, Harrison BJ, Wood SJ, Fornito A, Wellard RM, Pujol J, et al. Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorder. Arch Gen Psychiatry 2007, 64: 946-955.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 946-955
    • Yucel, M.1    Harrison, B.J.2    Wood, S.J.3    Fornito, A.4    Wellard, R.M.5    Pujol, J.6
  • 22
    • 1342289404 scopus 로고    scopus 로고
    • Anterior prefrontal cortex: Insights into function from anatomy and neuroimaging
    • 14976518 10.1038/nrn1343 1:CAS:528:DC%2BD2cXhsVWnsLY%3D
    • Ramnani N, Owen AM. Anterior prefrontal cortex: insights into function from anatomy and neuroimaging. Nat Rev Neurosci 2004, 5: 184-194.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 184-194
    • Ramnani, N.1    Owen, A.M.2
  • 23
    • 69249217668 scopus 로고    scopus 로고
    • Medial frontal and dorsal cortical morphometric abnormalities are related to obsessivecompulsive disorder
    • 19666084 10.1016/j.neulet.2009.08.012 1:CAS:528:DC%2BD1MXhtVKrsrrP
    • Koprivova J, Horacek J, Tintera J, Prasko J, Raszka M, Ibrahim I, et al. Medial frontal and dorsal cortical morphometric abnormalities are related to obsessivecompulsive disorder. Neurosci Lett 2009, 464: 62-66.
    • (2009) Neurosci Lett , vol.464 , pp. 62-66
    • Koprivova, J.1    Horacek, J.2    Tintera, J.3    Prasko, J.4    Raszka, M.5    Ibrahim, I.6
  • 24
    • 77954516879 scopus 로고    scopus 로고
    • Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disorders
    • 20603451 10.1001/archgenpsychiatry.2010.70
    • Radua J, van den Heuvel OA, Surguladze S, Mataix-Cols D. Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disorders. Arch Gen Psychiatry 2010, 67: 701-711.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 701-711
    • Radua, J.1    Van Den Heuvel, O.A.2    Surguladze, S.3    Mataix-Cols, D.4
  • 25
    • 77956951012 scopus 로고    scopus 로고
    • Regional gray and white matter volume abnormalities in obsessive-compulsive disorder: A voxelbased morphometry study
    • 20833001 10.1016/j.pscychresns.2010.06.011
    • Togao O, Yoshiura T, Nakao T, Nabeyama M, Sanematsu H, Nakagawa A, et al. Regional gray and white matter volume abnormalities in obsessive-compulsive disorder: a voxelbased morphometry study. Psychiatry Res 2010, 184: 29-37.
    • (2010) Psychiatry Res , vol.184 , pp. 29-37
    • Togao, O.1    Yoshiura, T.2    Nakao, T.3    Nabeyama, M.4    Sanematsu, H.5    Nakagawa, A.6
  • 26
    • 0034054982 scopus 로고    scopus 로고
    • Imaging cognition II: An empirical review of 275 PET and fMRI studies
    • 10769304 10.1162/08989290051137585 1:STN:280:DC%2BD3c3jtl2lug%3D%3D
    • Cabeza R, Nyberg L. Imaging cognition II: An empirical review of 275 PET and fMRI studies. J Cogn Neurosci 2000, 12: 1-47.
    • (2000) J Cogn Neurosci , vol.12 , pp. 1-47
    • Cabeza, R.1    Nyberg, L.2
  • 27
    • 0030660466 scopus 로고    scopus 로고
    • A neural basis for the retrieval of conceptual knowledge
    • 9347478 10.1016/S0028-3932(97)00085-7 1:STN:280:DyaK1c%2FgslSntQ%3D%3D
    • Tranel D, Damasio H, Damasio AR. A neural basis for the retrieval of conceptual knowledge. Neuropsychologia 1997, 35: 1319-1327.
    • (1997) Neuropsychologia , vol.35 , pp. 1319-1327
    • Tranel, D.1    Damasio, H.2    Damasio, A.R.3
  • 28
    • 53549126338 scopus 로고    scopus 로고
    • Greater regional cortical gray matter thickness in obsessive-compulsive disorder
    • 18797315 10.1097/WNR.0b013e3283112720
    • Narayan VM, Narr KL, Phillips OR, Thompson PM, Toga AW, Szeszko PR. Greater regional cortical gray matter thickness in obsessive-compulsive disorder. Neuroreport 2008, 19: 1551-1555.
    • (2008) Neuroreport , vol.19 , pp. 1551-1555
    • Narayan, V.M.1    Narr, K.L.2    Phillips, O.R.3    Thompson, P.M.4    Toga, A.W.5    Szeszko, P.R.6
  • 29
    • 0036534141 scopus 로고    scopus 로고
    • An fMRI study on the time-limited role of the medial temporal lobe in long-term topographical autobiographic memory
    • 11970809 10.1162/089892902317362010
    • Niki K, Luo J. An fMRI study on the time-limited role of the medial temporal lobe in long-term topographical autobiographic memory. J Cogn Neurosci 2002, 14: 500-507.
    • (2002) J Cogn Neurosci , vol.14 , pp. 500-507
    • Niki, K.1    Luo, J.2
  • 30
    • 35748948653 scopus 로고    scopus 로고
    • Memory and executive functioning in obsessive-compulsive disorder: A selective review
    • 17442402 10.1016/j.jad.2007.02.023
    • Olley A, Malhi G, Sachdev P. Memory and executive functioning in obsessive-compulsive disorder: a selective review. J Affect Disord 2007, 104: 15-23.
    • (2007) J Affect Disord , vol.104 , pp. 15-23
    • Olley, A.1    Malhi, G.2    Sachdev, P.3
  • 31
    • 74949083492 scopus 로고    scopus 로고
    • Human middle temporal cortex, perceptual bias, and perceptual memory for ambiguous three-dimensional motion
    • 20071541 10.1523/JNEUROSCI.4171-09.2010 1:CAS:528:DC%2BC3cXhtFahtbs%3D
    • Brascamp JW, Kanai R, Walsh V, van Ee R. Human middle temporal cortex, perceptual bias, and perceptual memory for ambiguous three-dimensional motion. J Neurosci 2010, 30: 760-766.
    • (2010) J Neurosci , vol.30 , pp. 760-766
    • Brascamp, J.W.1    Kanai, R.2    Walsh, V.3    Van Ee, R.4
  • 32
    • 34249055712 scopus 로고    scopus 로고
    • The medial temporal lobe and recognition memory
    • 17417939 10.1146/annurev.neuro.30.051606.094328 1:CAS:528: DC%2BD2sXptFKntbk%3D
    • Eichenbaum H, Yonelinas AP, Ranganath C. The medial temporal lobe and recognition memory. Annu Rev Neurosci 2007, 30: 123-152.
    • (2007) Annu Rev Neurosci , vol.30 , pp. 123-152
    • Eichenbaum, H.1    Yonelinas, A.P.2    Ranganath, C.3
  • 33
    • 63449100524 scopus 로고    scopus 로고
    • Brain changes in children and adolescents with obsessive-compulsive disorder before and after treatment: A voxel-based morphometric MRI study
    • 19321314 10.1016/j.pscychresns.2008.12.007
    • Lazaro L, Bargallo N, Castro-Fornieles J, Falcon C, Andres S, Calvo R, et al. Brain changes in children and adolescents with obsessive-compulsive disorder before and after treatment: a voxel-based morphometric MRI study. Psychiatry Res 2009, 172: 140-146.
    • (2009) Psychiatry Res , vol.172 , pp. 140-146
    • Lazaro, L.1    Bargallo, N.2    Castro-Fornieles, J.3    Falcon, C.4    Andres, S.5    Calvo, R.6
  • 34
    • 33750929375 scopus 로고    scopus 로고
    • Fractionating attentional control using event-related fMRI
    • 16436686 10.1093/cercor/bhj116
    • Hampshire A, Owen AM. Fractionating attentional control using event-related fMRI. Cereb Cortex 2006, 16: 1679-1689.
    • (2006) Cereb Cortex , vol.16 , pp. 1679-1689
    • Hampshire, A.1    Owen, A.M.2
  • 35
    • 38649135063 scopus 로고    scopus 로고
    • Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: The orbitofronto-striatal model revisited
    • 18061263 10.1016/j.neubiorev.2007.09.005
    • Menzies L, Chamberlain SR, Laird AR, Thelen SM, Sahakian BJ, Bullmore ET. Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited. Neurosci Biobehav Rev 2008, 32: 525-549.
    • (2008) Neurosci Biobehav Rev , vol.32 , pp. 525-549
    • Menzies, L.1    Chamberlain, S.R.2    Laird, A.R.3    Thelen, S.M.4    Sahakian, B.J.5    Bullmore, E.T.6
  • 36
    • 84868118056 scopus 로고    scopus 로고
    • Obsessive-compulsive symptom dimensions correlate to specific gray matter volumes in treatment-naive patients
    • 23040160 10.1016/j.jpsychires.2012.09.002
    • Alvarenga PG, do Rosario MC, Batistuzzo MC, Diniz JB, Shavitt RG, Duran FL, et al. Obsessive-compulsive symptom dimensions correlate to specific gray matter volumes in treatment-naive patients. J Psychiatr Res 2012, 46: 1635-1642.
    • (2012) J Psychiatr Res , vol.46 , pp. 1635-1642
    • Alvarenga, P.G.1    Do Rosario, M.C.2    Batistuzzo, M.C.3    Diniz, J.B.4    Shavitt, R.G.5    Duran, F.L.6
  • 37
    • 70450211847 scopus 로고    scopus 로고
    • Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorder
    • 19880927 10.1192/bjp.bp.108.055046
    • Radua J, Mataix-Cols D. Voxel-wise meta-analysis of grey matter changes in obsessive-compulsive disorder. Br J Psychiatry 2009, 195: 393-402.
    • (2009) Br J Psychiatry , vol.195 , pp. 393-402
    • Radua, J.1    Mataix-Cols, D.2
  • 38
    • 21744448853 scopus 로고    scopus 로고
    • White matter abnormalities in obsessive-compulsive disorder: A diffusion tensor imaging study
    • 15997020 10.1001/archpsyc.62.7.782
    • Szeszko PR, Ardekani BA, Ashtari M, Malhotra AK, Robinson DG, Bilder RM, et al. White matter abnormalities in obsessive-compulsive disorder: a diffusion tensor imaging study. Arch Gen Psychiatry 2005, 62: 782-790.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 782-790
    • Szeszko, P.R.1    Ardekani, B.A.2    Ashtari, M.3    Malhotra, A.K.4    Robinson, D.G.5    Bilder, R.M.6
  • 39
    • 54349111367 scopus 로고    scopus 로고
    • Gray matter structural alterations in psychotropic drug-naive pediatric obsessive-compulsive disorder: An optimized voxel-based morphometry study
    • 18413702 10.1176/appi.ajp.2008.08010033
    • Szeszko PR, Christian C, Macmaster F, Lencz T, Mirza Y, Taormina SP, et al. Gray matter structural alterations in psychotropic drug-naive pediatric obsessive-compulsive disorder: an optimized voxel-based morphometry study. Am J Psychiatry 2008, 165: 1299-1307.
    • (2008) Am J Psychiatry , vol.165 , pp. 1299-1307
    • Szeszko, P.R.1    Christian, C.2    Macmaster, F.3    Lencz, T.4    Mirza, Y.5    Taormina, S.P.6
  • 40
    • 46649116486 scopus 로고    scopus 로고
    • A 1H magnetic resonance spectroscopy study in adults with obsessive compulsive disorder: Relationship between metabolite concentrations and symptom severity
    • 18528631 10.1007/s00702-008-0045-4
    • Starck G, Ljungberg M, Nilsson M, Jonsson L, Lundberg S, Ivarsson T, et al. A 1H magnetic resonance spectroscopy study in adults with obsessive compulsive disorder: relationship between metabolite concentrations and symptom severity. J Neural Transm 2008, 115: 1051-1062.
    • (2008) J Neural Transm , vol.115 , pp. 1051-1062
    • Starck, G.1    Ljungberg, M.2    Nilsson, M.3    Jonsson, L.4    Lundberg, S.5    Ivarsson, T.6


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