PGE2 and PGF2α concentrations in human endometrial fluid as biomarkers for embryonic implantation

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 10, 2013, Pages 4123-4132

  Vilella, F ^a   Ramirez, L ^a   Berlanga, O ^a   Martinez S ^a   Alama P ^b   Meseguer, M ^b   Pellicer, A ^b   Simon C ^a,b,c  

^a Biomedical Research Institute Hospital Clinic de Valencia INCLIVA   (Spain)

^b UNIVERSITY OF VALENCIA   (Spain)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E SYNTHASE; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN F2 ALPHA RECEPTOR; PROSTAGLANDIN F2 ALPHA SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG;

ADULT; ANIMAL TISSUE; ARTICLE; BLASTOCYST; BODY FLUID; CELL ADHESION; CONTROLLED STUDY; ECTODERM; EMBRYO; EMBRYO ADHESION; EMBRYO TRANSFER; ENDOMETRIAL FLUID; ENZYME INHIBITION; ENZYME RELEASE; FEMALE; FERTILIZATION IN VITRO; HORMONAL REGULATION; HORMONE SUBSTITUTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IN VITRO STUDY; IN VIVO STUDY; INFERTILITY THERAPY; IUD INSERTER; LIQUID CHROMATOGRAPHY; MAJOR CLINICAL STUDY; MENSTRUAL CYCLE; MOUSE; NIDATION; NONHUMAN; OOCYTE DONATION; OVULATION INDUCTION; PILOT STUDY; PREGNANCY OUTCOME; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TROPHOECTODERM; WESTERN BLOTTING; ENDOMETRIUM; EXTRACELLULAR FLUID; METABOLISM; PHYSIOLOGY; PREGNANCY;

ADULT; BIOLOGICAL MARKERS; DINOPROST; DINOPROSTONE; EMBRYO IMPLANTATION; EMBRYO TRANSFER; ENDOMETRIUM; EXTRACELLULAR FLUID; FEMALE; HUMANS; OVULATION INDUCTION; PREGNANCY;

EID: 84885235527     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-2205     Document Type: Article

References (29)

1. World Health Organization. Progress in reproductive health research, number 63, 2003. http://www.who.int. Accessed September 20, 2010.
2. Norwitz ER, Schust DJ, Fisher SJ Implantation and the survival of early pregnancy. N Engl J Med. 2001; 345: 1400-1408.
3. Ferraretti AP, Goossens V, de Mouzon J, et al Assisted reproductive technology in Europe, 2008: results generated from European registers by ESHRE. Hum Reprod. 2012; 27: 2571-2584.
4. Society for Assisted Reproductive Technology. http://www.sart.org. Accessed September 20, 2010.
5. Wang H, Dey SK Roadmap to embryo implantation: clues from mouse models. Nat Rev Genet. 2006; 7: 185-199.
6. Jabbour HN, Sales KJ Prostaglandin receptor signalling and function in human endometrial pathology. Trends Endocrinol Metab. 2004; 15: 398-404.
7. Wang H, Dey SK Lipid signaling in embryo implantation. Prostaglandins Other Lipid Mediat. 2005; 77: 84-102.
8. Achache H, Tsafrir A, Prus D., Reich R, Revel A. Defective endometrial prostaglandin synthesis identified in patients with repeated implantation failure undergoing in vitro fertilization. Fertil Steril. 2010; 94: 1271-1278.
9. Catalano RD, Wilson MR, Boddy S.C., Jabbour HN Comprehensive expression analysis of prostanoid enzymes and receptors in the human endometrium across the menstrual cycle. Mol Hum Reprod. 2011; 17: 182-192.
10. Yoshizawa JM, Wong DTW. Salivary microRNAs and oral cancer detection. Methods Mol Biol. 2013; 936: 313-324.
11. Stevens T, Berk MP, Lopez R, et al Lipidomic profiling of serum and pancreatic fluid in chronic pancreatitis. Pancreas. 2012; 41: 518-522.
12. Simón C., Gimeno MJ, Mercader A, et al Embryonic regulation of integrins β3, α4, and α1 in human endometrial epithelial cells in vitro. J Clin Endocrinol Metab. 1997; 82: 2607-2616.
13. van der Gaast MH, Beier-Hellwig K, Fauser BCJM, Beier HM, Macklon NS Endometrial secretion aspiration prior to embryo transfer does not reduce implantation rates. Reprod Biomed Online. 2003; 7: 105-109.
14. Murakami M, Nakatani Y, Tanioka T., Kudo I. Prostaglandin E synthase. Prostaglandins Other Lipid Mediat. 2002; 68-69: 383-399.
15. Nishizawa M, Nakajima T, Yasuda K., et al. Close kinship of human 20α-hydroxysteroid dehydrogenase gene with three aldoketo reductase genes. Genes Cells. 2000; 5: 111-125.
16. Blesson CS, Büttner E, Masironi B., Sahlin L. Prostaglandin receptors EP and FP are regulated by estradiol and progesterone in the uterus of ovariectomized rats. Reprod Biol Endocrinol. 2012; 10: 3.
17. Lim H, Paria BC, Das S.K., et al Multiple female reproductive failures in cyclooxygenase 2-deficient mice. Cell. 1997; 91: 197-208.
18. Narumiya S, Sugimoto Y, Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev. 1999; 79: 1193-1226.
19. Martín J.C., Jasper MJ, Valbuena D, et al Increased adhesiveness in cultured endometrial-derived cells is related to the absence of moesin expression. Biol Reprod. 2000; 63: 1370-1376.
20. Díaz-Gimeno P., Horcajadas JA, Martinez-Conejero JA, et al A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature. Fertil Steril. 2011; 95: 50-60, 60.e1-e15.
21. Díaz-Gimeno P., Ruiz-Alonso M, Blesa D., et al The accuracy and reproducibility of the endometrial receptivity array is superior to histology as a diagnostic method for endometrial receptivity. Fertil Steril. 2013; 99(2): 508-517.
22. Bogan RL, Murphy MJ, Stouffer R.L., Hennebold JD Prostaglandin synthesis, metabolism, and signaling potential in the rhesus macaque corpus luteum throughout the luteal phase of the menstrual cycle. Endocrinology. 2008; 149: 5861-5871.
23. Chapdelaine P, Kang J, Boucher-Kovalik S, Caron N., Tremblay JP, Fortier MA Decidualization and maintenance of a functional prostaglandin system in human endometrial cell lines following transformation with SV40 large T antigen. Mol Hum Reprod. 2006; 12: 309-319.
24. Choi HJ, Park S-H, Kim J, Do K.H., Moon Y. Induction of human microsomal prostaglandin E synthase 1 by activated oncogene RhoA GTPase in A549 human epithelial cancer cells. Biochem Biophys Res Commun. 2011; 413(3): 448-453.
25. Song H, Lim H, Paria B.C., et al Cytosolic phospholipase A2α is crucial [correction of A2α deficiency is crucial] for "on-time" embryo implantation that directs subsequent development. Development. 2002; 129: 2879-2889.
26. Ye X, Hama K, Contos J.J., et al LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing. Nature. 2005; 435: 104-108.
27. Garrido-Gómez T, Dominguez F, Quiñonero A, et al. Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F-actin regulation. FASEB J. 2012; 26: 3715-3727.
28. Dominguez F, Simón C, Quiñonero A, et al. Human endometrial CD98 is essential for blastocyst adhesion. PLoS ONE. 2010; 5: e13380.
29. Vilella F, Herrero E, Torres J., la Torre-Ruiz de MA. Pkc1 and the upstream elements of the cell integrity pathway in Saccharomyces cerevisiae, Rom2 and Mtl1, are required for cellular responses to oxidative stress. J Biol Chem. 2005; 280: 9149-9159.