Carcinoembryonic antigen-related cell adhesion molecule 1 inhibits MMP-9-mediated blood-brain-barrier breakdown in a mouse model for ischemic stroke

Circulation Research

Volumn 113, Issue 8, 2013, Pages 1013-1022

  Ludewig, Peter ^a   Sedlacik, Jan ^a   Gelderblom, Mathias ^a   Bernreuther, Christian ^a   Korkusuz, Yücel ^a   Wagener, Christoph ^a   Gerloff, Christian ^a   Fiehler, Jens ^a   Magnus, Tim ^a   Horst, Andrea Kristina ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Animal model of human disease remodeling; Inflammation; Ischemic stroke; Neutrophils; Vascular system injuries

Indexed keywords

CARCINOEMBRYONIC ANTIGEN RELATED CELL ADHESION MOLECULE 1; EVANS BLUE; GELATINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN ISCHEMIA; CELL ISOLATION; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MIDDLE CEREBRAL ARTERY; MOUSE; NEUROIMAGING; NEUTROPHIL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; REPERFUSION INJURY; WILD TYPE; ZYMOGRAPHY;

ANIMAL MODEL OF HUMAN DISEASE REMODELING; INFLAMMATION; ISCHEMIC STROKE; NEUTROPHILS; VASCULAR SYSTEM INJURIES;

ANIMALS; ANTIGENS, CD; ATROPHY; BEHAVIOR, ANIMAL; BLOOD-BRAIN BARRIER; BRAIN EDEMA; CAPILLARY PERMEABILITY; CARCINOEMBRYONIC ANTIGEN; CELL ADHESION MOLECULES; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; HETEROCYCLIC COMPOUNDS, 1-RING; HUMANS; INFARCTION, MIDDLE CEREBRAL ARTERY; INFLAMMATION MEDIATORS; MAGNETIC RESONANCE IMAGING; MALE; MATRIX METALLOPROTEINASE 9; MATRIX METALLOPROTEINASE INHIBITORS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MOTOR ACTIVITY; NEUROLOGIC EXAMINATION; NEUTROPHIL ACTIVATION; NEUTROPHIL INFILTRATION; NEUTROPHILS; SULFONES; TIME FACTORS;

EID: 84885211216     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.113.301207     Document Type: Article

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