Exploring the structural insights on human laforin mutation K87A in lafora disease - A molecular dynamics study

Applied Biochemistry and Biotechnology

Volumn 171, Issue 4, 2013, Pages 874-882

  Srikumar, P S ^a   Rohini, K ^a  

^a AIMST UNIVERSITY   (Malaysia)

Author keywords

Conformation; Lafora Disease; Laforin; Molecular Dynamics Simulations; Mutant; Principal Component Analysis

Indexed keywords

ALIPHATIC AMINO ACIDS; CARBOHYDRATE-BINDING MODULES; LAFORIN; MOLECULAR DYNAMICS SIMULATIONS; MUTANT; PRINCIPLE COMPONENT ANALYSIS; ROOT MEAN SQUARE DEVIATIONS; SOLVENT ACCESSIBILITY;

AMINO ACIDS; CONFORMATIONS; HYDROGEN BONDS; PRINCIPAL COMPONENT ANALYSIS; PROTEINS;

MOLECULAR DYNAMICS;

AMINO ACID; CARBOHYDRATE BINDING PROTEIN; GLYCOGEN; LAFORIN; MUTANT PROTEIN; SOLVENT; UNCLASSIFIED DRUG;

ACIDITY; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; GENE MUTATION; GENE STRUCTURE; HYDROGEN BOND; MOLECULAR DYNAMICS; MYOCLONUS EPILEPSY; PRINCIPAL COMPONENT ANALYSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STABILITY; SIMULATION; VALIDATION STUDY;

HUMANS; LAFORA DISEASE; MOLECULAR DYNAMICS SIMULATION; MUTATION; PRINCIPAL COMPONENT ANALYSIS; PROTEIN STRUCTURE, SECONDARY; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR;

EID: 84885173246     PISSN: 02732289     EISSN: 15590291     Source Type: Journal    
DOI: 10.1007/s12010-013-0393-x     Document Type: Article

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