Australasian Resuscitation In Sepsis Evaluation trial statistical analysis plan

EMA - Emergency Medicine Australasia

Volumn 25, Issue 5, 2013, Pages 406-415

  Delaney, Anthony ^a,b   Peake, Sandra L ^c,d,e   Bellomo, Rinaldo ^c,f,g   Cameron, Peter ^c,h   Holdgate, Anna ^i,j   Howe, Belinda ^c   Higgins, Alisa ^c   Presneill, Jeffrey ^k   Webb, Steve ^c,l,m  

^a ROYAL NORTH SHORE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d QUEEN ELIZABETH HOSPITAL   (Australia)

^e UNIVERSITY OF ADELAIDE   (Australia)

^f UNIVERSITY OF MELBOURNE   (Australia)

^g AUSTIN HOSPITAL   (Australia)

^h ALFRED HOSPITAL   (Australia)

ⁱ UNIVERSITY OF NEW SOUTH WALES   (Australia)

^j LIVERPOOL HOSPITAL   (Australia)

^k MATER HOSPITAL   (Australia)

^l ROYAL PERTH HOSPITAL   (Australia)

^m UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

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Author keywords

Randomised controlled trial; Sepsis; Statistical analysis plan

Indexed keywords

CORTICOSTEROID; DOBUTAMINE; HYPERTENSIVE FACTOR; INFUSION FLUID;

ADVERSE OUTCOME; ANTIBIOTIC THERAPY; ARTERIAL LINE; ARTICLE; ARTIFICIAL VENTILATION; BLOOD TRANSFUSION; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; DISEASE SEVERITY; EARLY GOAL DIRECTED THERAPY; EMERGENCY WARD; HUMAN; MORTALITY; MULTICENTER STUDY; PATIENT CARE; PATIENT SAFETY; PRIORITY JOURNAL; PULMONARY ARTERY CATHETER; RANDOMIZED CONTROLLED TRIAL; RESUSCITATION; SEPSIS; STATISTICAL ANALYSIS; STUDY DESIGN; SURVIVAL TIME; THERAPY; TREATMENT CONTRAINDICATION; TREATMENT OUTCOME;

RANDOMISED CONTROLLED TRIAL; SEPSIS; STATISTICAL ANALYSIS PLAN;

AUSTRALASIA; DATA INTERPRETATION, STATISTICAL; HUMANS; RESUSCITATION; SEPSIS;

EID: 84885172343     PISSN: 17426731     EISSN: 17426723     Source Type: Journal    
DOI: 10.1111/1742-6723.12116     Document Type: Article

References (16)

1. Bellomo R, Cass A, Cole L etal. Intensity of continuous renal-replacement therapy in critically ill patients. N. Engl. J. Med. 2009; 361: 1627-1638.
2. Finfer S, Cass A, Gallagher M, Lee J, Su S, Bellomo R. The RENAL (Randomised Evaluation of Normal vs. Augmented Level of Replacement Therapy) study: statistical analysis plan. Crit. Care Resusc. 2009; 11: 58-66.
3. Finfer S, Heritier S. The NICE-SUGAR (Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation) Study: statistical analysis plan. Crit. Care Resusc. 2009; 11: 46-57.
4. Myburgh J, Li Q, Heritier S, Dan A, Glass P. Statistical analysis plan for the Crystalloid Versus Hydroxyethyl Starch Trial (CHEST). Crit. Care Resusc. 2012; 14: 44-52.
5. Thompson BT, Ranieri VM, Finfer S etal. Statistical analysis plan of PROWESS SHOCK study. Intensive Care Med. 2010; 36: 1972-1973.
6. Boutron I, Moher D, Altman DG, Schulz KF, Ravaud P. Extending the CONSORT statement to randomized trials of nonpharmacologic treatment: explanation and elaboration. Ann. Intern. Med. 2008; 148: 295-309.
7. Boutron I, Moher D, Altman DG, Schulz KF, Ravaud P. Methods and processes of the CONSORT Group: example of an extension for trials assessing nonpharmacologic treatments. Ann. Intern. Med. 2008; 148: W60-66.
8. Bone RC, Balk RA, Cerra FB etal. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992; 101: 1644-1655.
9. The NICE-SUGAR investigators. Intensive versus conventional glucose control in critically ill patients. N. Engl. J. Med. 2009; 360: 1283-1297.
10. Finfer S, Bellomo R, Lipman J, French C, Dobb G, Myburgh J. Adult-population incidence of severe sepsis in Australian and New Zealand intensive care units. Intensive Care Med. 2004; 30: 589-596.
11. Peake SL, Bailey M, Bellomo R etal. Australasian resuscitation of sepsis evaluation (ARISE): a multi-centre, prospective, inception cohort study. Resuscitation 2009; 80: 811-818.
12. The ARISE investigators, The ANZICS APD management committee. The outcome of patients with sepsis and septic shock presenting to emergency departments in Australia and New Zealand. Crit. Care Resusc. 2007; 9: 8-18.
13. Weycker D, Akhras KS, Edelsberg J, Angus DC, Oster G. Long-term mortality and medical care charges in patients with severe sepsis. Crit. Care Med. 2003; 31: 2316-2323.
14. Angus DC, Laterre PF, Helterbrand J etal. The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis. Crit. Care Med. 2004; 32: 2199-2206.
15. Rivers E, Nguyen B, Havstad S etal. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N. Engl. J. Med. 2001; 345: 1368-1377.
16. Reade MC, Huang DT, Bell D etal. Variability in management of early severe sepsis. Emerg. Med. J. 2010; 27: 110-115.