메뉴 건너뛰기




Volumn 68, Issue 6, 2013, Pages 1364-1372

Safety and feasibility of treatment simplification to atazanavir/ ritonavir1lamivudine in hiv-infected patients on stable treatment with two nucleos(t)ide reverse transcriptase inhibitors1atazanavir/ ritonavir with virological suppression (atazanavir and lamivudine for treatment simplification, atlas pilot study)

Author keywords

Combined antiretroviral therapy; Dual therapy; Long term tolerability; Switch

Indexed keywords

ATAZANAVIR PLUS RITONAVIR; BILIRUBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LAMIVUDINE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; VIRUS RNA;

EID: 84885150446     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt007     Document Type: Article
Times cited : (49)

References (52)
  • 1
    • 33748116898 scopus 로고    scopus 로고
    • Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study
    • Palella FJ Jr, Baker RK, Moorman AC, et al. Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV outpatient study. J Acquir Immune Defic Syndr 2006; 43: 27-34.
    • (2006) J Acquir Immune Defic Syndr , vol.43 , pp. 27-34
    • Palella, F.J.1    Baker, R.K.2    Moorman, A.C.3
  • 2
    • 84885126061 scopus 로고    scopus 로고
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. Department of Health and Human Services; March 27, (21 November 2012, date last accessed)
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents. Department of Health and Human Services; March 27, 2012. http:// www.aidsinfo.nih.gov/contentfiles/lvguidelines/adultandadolescentgl.pdf (21 November 2012, date last accessed).
    • (2012)
  • 3
    • 84885152065 scopus 로고    scopus 로고
    • European AIDS Clinical Society (EACS). Guidelines: Clinical Management and Treatment of HIV Infected Adults in Europe, Prevention and Management of Non-Infectious Comorbidities in HIV, Version 6.1, November (21 November 2012, date last accessed)
    • European AIDS Clinical Society (EACS). Guidelines: Clinical Management and Treatment of HIV Infected Adults in Europe, Prevention and Management of Non-Infectious Comorbidities in HIV, Version 6.1, November 2012. http://www.europeanaidsclinicalsociety.org/images/stories/ EACS-Pdf/EACSGuidelines-v6.1-English-Nov2012.pdf (21 November 2012, date last accessed).
    • (2012)
  • 4
    • 84885164303 scopus 로고    scopus 로고
    • British HIV Association. British HIV Association Guidelines for the Treatment of HIV-1-Positive Adults With Antiretroviral Therapy (21 November 2012, date last accessed)
    • British HIV Association. British HIV Association Guidelines for the Treatment of HIV-1-Positive Adults With Antiretroviral Therapy 2012. http://www.bhiva.org/documents/Guidelines/Treatment/2012/hiv1029_2.pdf (21 November 2012, date last accessed).
    • (2012)
  • 5
    • 84885105131 scopus 로고    scopus 로고
    • Linee Guida Italiane sull' Utilizzo dei Farmaci Antiretrovirali e sulla Gestione Diagnostico-clinica delle Persone con Infezione da HIV-1, Luglio (21 November 2012, date last accessed)
    • Linee Guida Italiane sull' Utilizzo dei Farmaci Antiretrovirali e sulla Gestione Diagnostico-clinica delle Persone con Infezione da HIV-1, Luglio 2012. http://www.salute.gov.it/imgs/C_17_pubblicazioni_1793_allegato.pdf (21 November 2012, date last accessed).
    • (2012)
  • 6
    • 59849124358 scopus 로고    scopus 로고
    • HIV monotherapy with ritonavir-boosted protease inhibitors: a systematic review
    • Bierman WF, van Agtmael MA, Nijhuis M, et al. HIV monotherapy with ritonavir-boosted protease inhibitors: a systematic review. AIDS 2009; 23: 279-91.
    • (2009) AIDS , vol.23 , pp. 279-91
    • Bierman, W.F.1    van Agtmael, M.A.2    Nijhuis, M.3
  • 7
    • 27444444039 scopus 로고    scopus 로고
    • Lopinavir/ritonavir as single-drug therapy for maintenance of HIV-1 viral suppression: 48-week results of a randomized, controlled, open-label, proof-of-concept pilot clinical trial (OK Study)
    • Arribas JR, Pulido F, Delgado R, et al. Lopinavir/ritonavir as single-drug therapy for maintenance of HIV-1 viral suppression: 48-week results of a randomized, controlled, open-label, proof-of-concept pilot clinical trial (OK Study). J Acquir Immune Defic Syndr 2005; 40: 280-7.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , pp. 280-7
    • Arribas, J.R.1    Pulido, F.2    Delgado, R.3
  • 8
    • 37549030881 scopus 로고    scopus 로고
    • Lopinavir-ritonavir monotherapy versus lopinavir-ritonavir and two nucleosides for maintenance therapy of HIV
    • Pulido F, Arribas JR, Delgado R, et al. Lopinavir-ritonavir monotherapy versus lopinavir-ritonavir and two nucleosides for maintenance therapy of HIV. AIDS 2008; 22: F1-9.
    • (2008) AIDS , vol.22
    • Pulido, F.1    Arribas, J.R.2    Delgado, R.3
  • 9
    • 79959983491 scopus 로고    scopus 로고
    • Viral response in stable patients switching to fosamprenavir/ritonavir monotherapy (the FONT Study)
    • Saumoy M, Tiraboschi J, Gutierrez M, et al. Viral response in stable patients switching to fosamprenavir/ritonavir monotherapy (the FONT Study). HIV Med 2011; 12: 438-41.
    • (2011) HIV Med , vol.12 , pp. 438-41
    • Saumoy, M.1    Tiraboschi, J.2    Gutierrez, M.3
  • 10
    • 77957230936 scopus 로고    scopus 로고
    • Efficacy of darunavir/ ritonavir maintenance monotherapy in patients with HIV-1 viral suppression: a randomized open-label, noninferiority trial, MONOI-ANRS 136
    • Katlama C, Valantin MA, Algarte-Genin M, et al. Efficacy of darunavir/ ritonavir maintenance monotherapy in patients with HIV-1 viral suppression: a randomized open-label, noninferiority trial, MONOI-ANRS 136. AIDS 2010; 24: 2365-74.
    • (2010) AIDS , vol.24 , pp. 2365-74
    • Katlama, C.1    Valantin, M.A.2    Algarte-Genin, M.3
  • 11
    • 74249086332 scopus 로고    scopus 로고
    • The MONET trial: darunavir/ ritonavir with or without nucleoside analogues, for patients with HIV RNA below 50 copies/ml
    • Arribas JR, Horban A, Gerstoft J, et al. The MONET trial: darunavir/ ritonavir with or without nucleoside analogues, for patients with HIV RNA below 50 copies/ml. AIDS 2010; 24: 223-30.
    • (2010) AIDS , vol.24 , pp. 223-30
    • Arribas, J.R.1    Horban, A.2    Gerstoft, J.3
  • 12
    • 84863199008 scopus 로고    scopus 로고
    • The MONET trial: week 144 analysis of the efficacy of darunavir/ritonavir (DRV/r) monotherapy versus DRV/r plus two nucleoside reverse transcriptase inhibitors, for patients with viral load ,50 HIV-1 RNA copies/mL at baseline
    • Arribas J, Clumeck N, Nelson M, et al. The MONET trial: week 144 analysis of the efficacy of darunavir/ritonavir (DRV/r) monotherapy versus DRV/r plus two nucleoside reverse transcriptase inhibitors, for patients with viral load ,50 HIV-1 RNA copies/mL at baseline. HIV Med 2012; 13: 398-405.
    • (2012) HIV Med , vol.13 , pp. 398-405
    • Arribas, J.1    Clumeck, N.2    Nelson, M.3
  • 13
    • 34250025874 scopus 로고    scopus 로고
    • The role ofcompartment penetration in PI-monotherapy: the Atazanavir-Ritonavir Monomaintenance (ATARITMO) Trial
    • Vernazza P, Daneel S, SchifferVet al. The role ofcompartment penetration in PI-monotherapy: the Atazanavir-Ritonavir Monomaintenance (ATARITMO) Trial. AIDS 2007; 21: 1309-15.
    • (2007) AIDS , vol.21 , pp. 1309-15
    • Vernazza, P.1    Daneel, S.2    Schiffer, V.3
  • 14
    • 65649151755 scopus 로고    scopus 로고
    • Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: final 48-week clinical and virologic outcomes
    • Wilkin TJ, McKinnon JE, DiRienzo AG, et al. Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: final 48-week clinical and virologic outcomes. J Infect Dis 2009; 199: 866-71.
    • (2009) J Infect Dis , vol.199 , pp. 866-71
    • Wilkin, T.J.1    McKinnon, J.E.2    DiRienzo, A.G.3
  • 15
    • 34147096424 scopus 로고    scopus 로고
    • Early virologic rebound in a pilot trial of ritonavir-boosted atazanavir as maintenance monotherapy
    • Karlström O, Josephson F, Sönnerborg A. Early virologic rebound in a pilot trial of ritonavir-boosted atazanavir as maintenance monotherapy. J Acquir Immune Defic Syndr 2007; 44: 417-22.
    • (2007) J Acquir Immune Defic Syndr , vol.44 , pp. 417-22
    • Karlström, O.1    Josephson, F.2    Sönnerborg, A.3
  • 16
    • 84885167402 scopus 로고    scopus 로고
    • Atazanavir/ritonavir monotherapy for maintenance of virologic suppression: 48 week primary analysis of the 96 week multicenter, open-label, single-arm, pilot OREY study
    • In: Abstracts of the Twelfth EACS Conference, Cologne, Germany, Oral PS4/6
    • Pulido F, Serrano O, Rivero A, et al. Atazanavir/ritonavir monotherapy for maintenance of virologic suppression: 48 week primary analysis of the 96 week multicenter, open-label, single-arm, pilot OREY study. In: Abstracts of the Twelfth EACS Conference, Cologne, Germany, 2009. Oral PS4/6.
    • (2009)
    • Pulido, F.1    Serrano, O.2    Rivero, A.3
  • 17
    • 77649201378 scopus 로고    scopus 로고
    • Once-daily atazanavir/ritonavir compared with twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 96-week efficacy and safety results of the CASTLE study
    • Molina JM, Andrade-Villanueva J, Echevarria J, et al. Once-daily atazanavir/ritonavir compared with twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 96-week efficacy and safety results of the CASTLE study. J Acquir Immune Defic Syndr 2010; 53: 323-32.
    • (2010) J Acquir Immune Defic Syndr , vol.53 , pp. 323-32
    • Molina, J.M.1    Andrade-Villanueva, J.2    Echevarria, J.3
  • 18
    • 79955440277 scopus 로고    scopus 로고
    • Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1
    • Daar ES, Tierney C, Fischl MA, et al. Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1. Ann Intern Med 2011; 154: 445-56.
    • (2011) Ann Intern Med , vol.154 , pp. 445-56
    • Daar, E.S.1    Tierney, C.2    Fischl, M.A.3
  • 19
    • 84859231900 scopus 로고    scopus 로고
    • 2011 update of the drug resistance mutations in HIV-1
    • Johnson VA, Calvez V, Günthard HF, et al. 2011 update of the drug resistance mutations in HIV-1. Top Antivir Med 2011; 19: 156-64.
    • (2011) Top Antivir Med , vol.19 , pp. 156-64
    • Johnson, V.A.1    Calvez, V.2    Günthard, H.F.3
  • 20
    • 2442657656 scopus 로고    scopus 로고
    • Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens
    • Colonno R, Rose R, McLaren C, et al. Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens. J Infect Dis 2004; 189: 1802-10.
    • (2004) J Infect Dis , vol.189 , pp. 1802-10
    • Colonno, R.1    Rose, R.2    McLaren, C.3
  • 21
    • 24144434946 scopus 로고    scopus 로고
    • Molecular basis for increased susceptibility of isolates with atazanavir resistance-conferring substitution I50L to other protease inhibitors
    • Yanchunas J Jr, Langley DR, Tao L, et al. Molecular basis for increased susceptibility of isolates with atazanavir resistance-conferring substitution I50L to other protease inhibitors. Antimicrob Agents Chemother 2005; 49: 3825-32.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3825-32
    • Yanchunas, J.1    Langley, D.R.2    Tao, L.3
  • 22
    • 0034947293 scopus 로고    scopus 로고
    • Increased drug susceptibility of HIV-1 reverse transcriptase mutants containing M184V and zidovudineassociated mutations: analysis of enzyme processivity, chain-terminator removal and viral replication
    • Naeger LK, Margot NA, Miller MD. Increased drug susceptibility of HIV-1 reverse transcriptase mutants containing M184V and zidovudineassociated mutations: analysis of enzyme processivity, chain-terminator removal and viral replication. Antivir Ther 2001; 6: 115-26.
    • (2001) Antivir Ther , vol.6 , pp. 115-26
    • Naeger, L.K.1    Margot, N.A.2    Miller, M.D.3
  • 23
    • 8944256865 scopus 로고    scopus 로고
    • Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients
    • Kuritzkes DR, Quinn JB, Benoit SL, et al. Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients. AIDS 1996; 10: 975-81.
    • (1996) AIDS , vol.10 , pp. 975-81
    • Kuritzkes, D.R.1    Quinn, J.B.2    Benoit, S.L.3
  • 24
    • 1542327561 scopus 로고    scopus 로고
    • Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients
    • Miller MD, Margot N, Lu B, et al. Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients. J Infect Dis 2004; 189: 837-46.
    • (2004) J Infect Dis , vol.189 , pp. 837-46
    • Miller, M.D.1    Margot, N.2    Lu, B.3
  • 25
    • 84885120041 scopus 로고    scopus 로고
    • Division of AIDS (DAIDS). Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events. Publish Date: December, (21 November 2012, date last accessed)
    • Division of AIDS (DAIDS). Division of AIDS Table for Grading the Severity of Adult and Pediatric Adverse Events. Publish Date: December, 2004. http://www.niaid.nih.gov/LabsAndResources/resources/DAIDSClinRsrch/ Documents/daidsaegradingtable.pdf (21 November 2012, date last accessed).
    • (2004)
  • 26
    • 75149148053 scopus 로고    scopus 로고
    • Atazanavir Ctrough is associated with efficacy and safety: definition of therapeutic range
    • In: Abstracts of the Twelfth Conference on Retroviruses and Opportunistic Infections, Boston, MA, USA, Abstract 645. Foundation for Retrovirology and Human Health, Alexandria, VA, USA
    • Gonzalez de Requena D, Bonora S, Canta F, et al. Atazanavir Ctrough is associated with efficacy and safety: definition of therapeutic range. In: Abstracts of the Twelfth Conference on Retroviruses and Opportunistic Infections, Boston, MA, USA, 2005. Abstract 645. Foundation for Retrovirology and Human Health, Alexandria, VA, USA.
    • (2005)
    • Gonzalez de Requena, D.1    Bonora, S.2    Canta, F.3
  • 27
    • 77953165375 scopus 로고    scopus 로고
    • Mid-dosing interval concentration of atazanavir and virological outcome in patients treated for HIV-1 infection
    • Fabbiani M, Di Giambenedetto S, Ragazzoni E, et al. Mid-dosing interval concentration of atazanavir and virological outcome in patients treated for HIV-1 infection. HIV Med 2010; 11: 326-33.
    • (2010) HIV Med , vol.11 , pp. 326-33
    • Fabbiani, M.1    Di Giambenedetto, S.2    Ragazzoni, E.3
  • 28
    • 0033574249 scopus 로고    scopus 로고
    • A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation
    • Levey AS, Bosch JP, Lewis JB, et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Ann Intern Med 1999; 130: 461-70.
    • (1999) Ann Intern Med , vol.130 , pp. 461-70
    • Levey, A.S.1    Bosch, J.P.2    Lewis, J.B.3
  • 29
    • 67249131485 scopus 로고    scopus 로고
    • Pharmacokinetic variability of antiretroviral drugs and correlation with virological outcome: 2 years of experience in routine clinical practice
    • Fabbiani M, Di Giambenedetto S, Bracciale L, et al. Pharmacokinetic variability of antiretroviral drugs and correlation with virological outcome: 2 years of experience in routine clinical practice. J Antimicrob Chemother 2009; 64: 109-17.
    • (2009) J Antimicrob Chemother , vol.64 , pp. 109-17
    • Fabbiani, M.1    Di Giambenedetto, S.2    Bracciale, L.3
  • 30
    • 77958518603 scopus 로고    scopus 로고
    • Asymmetry of the regimen is correlated to self-reported suboptimal adherence: results from AdUCSC, a cohort study on adherence in Italy
    • Murri R, Cingolani A, De Luca A, et al. Asymmetry of the regimen is correlated to self-reported suboptimal adherence: results from AdUCSC, a cohort study on adherence in Italy. J Acquir Immune Defic Syndr 2010; 55: 411-2.
    • (2010) J Acquir Immune Defic Syndr , vol.55 , pp. 411-2
    • Murri, R.1    Cingolani, A.2    De Luca, A.3
  • 31
    • 0035894169 scopus 로고    scopus 로고
    • Self-reported symptoms and medication side effects influence adherence to highly active antiretroviral therapy in persons with HIV infection
    • Ammassari A, Murri R, Pezzotti P, et al. Self-reported symptoms and medication side effects influence adherence to highly active antiretroviral therapy in persons with HIV infection. J Acquir Immune Defic Syndr 2001; 28: 445-9.
    • (2001) J Acquir Immune Defic Syndr , vol.28 , pp. 445-9
    • Ammassari, A.1    Murri, R.2    Pezzotti, P.3
  • 32
    • 77956598120 scopus 로고    scopus 로고
    • Practice effects in healthy adults: a longitudinal study on frequent repetitive cognitive testing
    • Bartels C, Wegrzyn M, Wiedl A, et al. Practice effects in healthy adults: a longitudinal study on frequent repetitive cognitive testing. BMC Neurosci 2010; 11: 118.
    • (2010) BMC Neurosci , vol.11 , pp. 118
    • Bartels, C.1    Wegrzyn, M.2    Wiedl, A.3
  • 33
    • 84873254823 scopus 로고    scopus 로고
    • Cardiovascular risk factors and carotid intima-media thickness are associated with lower cognitive performance in HIV-infected patients
    • doi:10.1111/j. 1468-1293.2012.01044.x
    • Fabbiani M, Ciccarelli N, Tana M, et al. Cardiovascular risk factors and carotid intima-media thickness are associated with lower cognitive performance in HIV-infected patients. HIV Med 2012; doi:10.1111/j. 1468-1293.2012.01044.x.
    • (2012) HIV Med
    • Fabbiani, M.1    Ciccarelli, N.2    Tana, M.3
  • 34
    • 84867328279 scopus 로고    scopus 로고
    • Increased ophthalmic artery resistance index is associated with cognitive impairment in HIV-infected patients
    • Grima P, Fabbiani M, Ciccarelli N, et al. Increased ophthalmic artery resistance index is associated with cognitive impairment in HIV-infected patients. J Infect 2012; 65: 439-46.
    • (2012) J Infect , vol.65 , pp. 439-46
    • Grima, P.1    Fabbiani, M.2    Ciccarelli, N.3
  • 35
    • 79953049661 scopus 로고    scopus 로고
    • Tenofovir discontinuation could predispose to urolithiasis in atazanavir-treated patients
    • Fabbiani M, Bracciale L, Doino M, et al. Tenofovir discontinuation could predispose to urolithiasis in atazanavir-treated patients. J Infect 2011; 62: 319-21.
    • (2011) J Infect , vol.62 , pp. 319-21
    • Fabbiani, M.1    Bracciale, L.2    Doino, M.3
  • 36
    • 34248547693 scopus 로고    scopus 로고
    • Atazanavir-associated nephrolithiasis: cases from the US Food and Drug Administration's Adverse Event Reporting System
    • Chan-Tack KM, Truffa MM, Struble KA, et al. Atazanavir-associated nephrolithiasis: cases from the US Food and Drug Administration's Adverse Event Reporting System. AIDS 2007; 21: 1215-8.
    • (2007) AIDS , vol.21 , pp. 1215-8
    • Chan-Tack, K.M.1    Truffa, M.M.2    Struble, K.A.3
  • 37
    • 80052897871 scopus 로고    scopus 로고
    • Abacavir/lamivudine versus tenofovir DF/emtricitabine as part of combination regimens for initial treatment of HIV: final results
    • Sax PE, Tierney C, Collier AC, et al. Abacavir/lamivudine versus tenofovir DF/emtricitabine as part of combination regimens for initial treatment of HIV: final results. J Infect Dis 2011; 204: 1191-201.
    • (2011) J Infect Dis , vol.204 , pp. 1191-201
    • Sax, P.E.1    Tierney, C.2    Collier, A.C.3
  • 38
    • 72449169534 scopus 로고    scopus 로고
    • Efficacy and safety of boosted and unboosted atazanavir-containing antiretroviral regimens in real life: results from a multicentre cohort study
    • Giuntini R, Martinelli C, Ricci E, et al. Efficacy and safety of boosted and unboosted atazanavir-containing antiretroviral regimens in real life: results from a multicentre cohort study. HIV Med 2010; 11: 40-5.
    • (2010) HIV Med , vol.11 , pp. 40-5
    • Giuntini, R.1    Martinelli, C.2    Ricci, E.3
  • 39
    • 84885163375 scopus 로고    scopus 로고
    • ATV-containing ART is not associated with an increased risk of cardio- or cerebro-vascular events in the D:A:D Study
    • In: Abstracts of the Nineteenth Conference on Retroviruses and Opportunistic Infections, Seattle, WA, USA, Abstract 823. Foundation for Retrovirology and Human Health, Alexandria, VA, USA
    • D'Arminio Monforte A, Reiss P, Ryom L, et al. ATV-containing ART is not associated with an increased risk of cardio- or cerebro-vascular events in the D:A:D Study. In: Abstracts of the Nineteenth Conference on Retroviruses and Opportunistic Infections, Seattle, WA, USA, 2012. Abstract 823. Foundation for Retrovirology and Human Health, Alexandria, VA, USA.
    • (2012)
    • D'Arminio Monforte, A.1    Reiss, P.2    Ryom, L.3
  • 40
    • 79951530133 scopus 로고    scopus 로고
    • Lipid-lowering effect of tenofovir in HIV-infected patients
    • Fabbiani M, Bracciale L, Doino M, et al. Lipid-lowering effect of tenofovir in HIV-infected patients. J Antimicrob Chemother 2011; 66: 682-3.
    • (2011) J Antimicrob Chemother , vol.66 , pp. 682-3
    • Fabbiani, M.1    Bracciale, L.2    Doino, M.3
  • 41
    • 77954319572 scopus 로고    scopus 로고
    • A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206
    • Tungsiripat M, Kitch D, Glesby MJ, et al. A pilot study to determine the impact on dyslipidemia of adding tenofovir to stable background antiretroviral therapy: ACTG 5206. AIDS 2010; 24: 1781-4.
    • (2010) AIDS , vol.24 , pp. 1781-4
    • Tungsiripat, M.1    Kitch, D.2    Glesby, M.J.3
  • 42
    • 77950688114 scopus 로고    scopus 로고
    • The effect of tenofovir disoproxil fumarate on whole-body insulin sensitivity, lipids and adipokines in healthy volunteers
    • Randell PA, Jackson AG, Zhong L, et al. The effect of tenofovir disoproxil fumarate on whole-body insulin sensitivity, lipids and adipokines in healthy volunteers. Antivir Ther 2010; 15: 227-33.
    • (2010) Antivir Ther , vol.15 , pp. 227-33
    • Randell, P.A.1    Jackson, A.G.2    Zhong, L.3
  • 43
    • 2542502584 scopus 로고    scopus 로고
    • Interactions between atazanavirritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients
    • Taburet AM, Piketty C, Chazallon C, et al. Interactions between atazanavirritonavir and tenofovir in heavily pretreated human immunodeficiency virus-infected patients. Antimicrob Agents Chemother 2004; 48: 2091-6.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 2091-6
    • Taburet, A.M.1    Piketty, C.2    Chazallon, C.3
  • 44
    • 68449100595 scopus 로고    scopus 로고
    • Metabolic bone disease in HIV infection
    • Borderi M, Gibellini D, Vescini F, et al. Metabolic bone disease in HIV infection. AIDS 2009; 23: 1297-310.
    • (2009) AIDS , vol.23 , pp. 1297-310
    • Borderi, M.1    Gibellini, D.2    Vescini, F.3
  • 45
    • 79957494036 scopus 로고    scopus 로고
    • Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: AIDS Clinical Trials Group A5224s, a substudy of ACTG A5202
    • McComsey GA, Kitch D, Daar ES, et al. Bone mineral density and fractures in antiretroviral-naive persons randomized to receive abacavir-lamivudine or tenofovir disoproxil fumarate-emtricitabine along with efavirenz or atazanavir-ritonavir: AIDS Clinical Trials Group A5224s, a substudy of ACTG A5202. J Infect Dis 2011; 203: 1791-801.
    • (2011) J Infect Dis , vol.203 , pp. 1791-801
    • McComsey, G.A.1    Kitch, D.2    Daar, E.S.3
  • 46
    • 75649093029 scopus 로고    scopus 로고
    • Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: the data collection on adverse events of anti-HIV drugs (D:A:D) study
    • Worm SW, Sabin C, Weber R, et al. Risk of myocardial infarction in patients with HIV infection exposed to specific individual antiretroviral drugs from the 3 major drug classes: the data collection on adverse events of anti-HIV drugs (D:A:D) study. J Infect Dis 2010; 201: 318-30.
    • (2010) J Infect Dis , vol.201 , pp. 318-30
    • Worm, S.W.1    Sabin, C.2    Weber, R.3
  • 47
    • 79951817556 scopus 로고    scopus 로고
    • Low vitamin D among HIV-infected adults: prevalence of and risk factors for low vitamin D levels in a cohort of HIV-infected adults and comparison to prevalence among adults in the US general population
    • Dao CN, Patel P, Overton ET, et al. Low vitamin D among HIV-infected adults: prevalence of and risk factors for low vitamin D levels in a cohort of HIV-infected adults and comparison to prevalence among adults in the US general population. Clin Infect Dis 2011; 52: 396-405.
    • (2011) Clin Infect Dis , vol.52 , pp. 396-405
    • Dao, C.N.1    Patel, P.2    Overton, E.T.3
  • 48
    • 79951820590 scopus 로고    scopus 로고
    • The effect of antiretrovirals on vitamin D
    • Yin M, Stein E. The effect of antiretrovirals on vitamin D. Clin Infect Dis 2011; 52: 406-8.
    • (2011) Clin Infect Dis , vol.52 , pp. 406-8
    • Yin, M.1    Stein, E.2
  • 49
    • 33750227103 scopus 로고    scopus 로고
    • A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy
    • Moyle GJ, Sabin CA, Cartledge J, et al. A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy. AIDS 2006; 20: 2043-50.
    • (2006) AIDS , vol.20 , pp. 2043-50
    • Moyle, G.J.1    Sabin, C.A.2    Cartledge, J.3
  • 50
    • 44449163367 scopus 로고    scopus 로고
    • Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/ lamivudine-a Staccato trial substudy
    • Ananworanich J, Nuesch R, CôtéHC, et al. Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/ lamivudine-a Staccato trial substudy. J Antimicrob Chemother 2008; 61: 1340-3.
    • (2008) J Antimicrob Chemother , vol.61 , pp. 1340-3
    • Ananworanich, J.1    Nuesch, R.2    Côté, H.C.3
  • 51
    • 65749093276 scopus 로고    scopus 로고
    • Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen
    • Gerschenson M, Kim C, Berzins B, et al. Mitochondrial function, morphology and metabolic parameters improve after switching from stavudine to a tenofovir-containing regimen. J Antimicrob Chemother 2009; 63: 1244-50.
    • (2009) J Antimicrob Chemother , vol.63 , pp. 1244-50
    • Gerschenson, M.1    Kim, C.2    Berzins, B.3
  • 52
    • 84861710765 scopus 로고    scopus 로고
    • Changes in body composition and mitochondrial DNA in HIV-1-infected patients switching to fixed-dose abacavir/lamivudine or tenofovir/emtricitabine: a substudy of the BICOMBO trial
    • Curran A, Martinez E, Podzamczer D, et al. Changes in body composition and mitochondrial DNA in HIV-1-infected patients switching to fixed-dose abacavir/lamivudine or tenofovir/emtricitabine: a substudy of the BICOMBO trial. Antivir Ther 2012; 17: 711-8.
    • (2012) Antivir Ther , vol.17 , pp. 711-8
    • Curran, A.1    Martinez, E.2    Podzamczer, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.