메뉴 건너뛰기




Volumn 9, Issue 10, 2013, Pages 2049-2059

Cross reactivity of serum antibody responses elicited by DNA vaccines expressing HA antigens from H1N1 subtype influenza vaccines in the past 30 years

Author keywords

Antibody; DNA vaccine; H1N1; Hemagglutinin; Influenza

Indexed keywords

DNA VACCINE; HORSERADISH PEROXIDASE; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; POLYETHYLENEIMINE;

EID: 84885141966     PISSN: 21645515     EISSN: 2164554X     Source Type: Journal    
DOI: 10.4161/hv.25735     Document Type: Article
Times cited : (9)

References (39)
  • 1
    • 84866112420 scopus 로고    scopus 로고
    • New treatments for influenza
    • PMID:22973873
    • Barik S. New treatments for influenza. BMC Med 2012;10:104; PMID:22973873; http://dx.doi.org/10.1186/1741-7015-10-104
    • (2012) BMC Med , vol.10 , pp. 104
    • Barik, S.1
  • 3
    • 18844389483 scopus 로고    scopus 로고
    • Influenza vaccines: Recent advances in production technologies
    • PMID: 15660212
    • Bardiya N, Bae JH. Influenza vaccines: recent advances in production technologies. Appl Microbiol Biotechnol 2005;67:299-305; PMID: 15660212; http://dx.doi.org/10.1007/s0025 3-004-1874-1
    • (2005) Appl Microbiol Biotechnol , vol.67 , pp. 299-305
    • Bardiya, N.1    Bae, J.H.2
  • 4
    • 79960997012 scopus 로고    scopus 로고
    • Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccinespecific antibodies
    • PMID:21785218
    • Sasaki S, Sullivan M, Narvaez CF, Holmes TH, Furman D, Zheng NY, et al. Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccinespecific antibodies. J Clin Invest 2011;121:3109-19; PMID:21785218; http://dx.doi.org/10.1172/JCI57834
    • (2011) J Clin Invest , vol.121 , pp. 3109-3119
    • Sasaki, S.1    Sullivan, M.2    Narvaez, C.F.3    Holmes, T.H.4    Furman, D.5    Zheng, N.Y.6
  • 5
    • 79751480796 scopus 로고    scopus 로고
    • The relative efficacy of trivalent live attenuated and inactivated influenza vaccines in children and adults
    • PMID:21306569
    • Ambrose CS, Levin MJ, Belshe RB. The relative efficacy of trivalent live attenuated and inactivated influenza vaccines in children and adults. Influenza Other Respi Viruses 2011;5:67-75; PMID:21306569; http://dx.doi.org/10.1111/j. 1750-2659.2010.00183.x
    • (2011) Influenza Other Respi Viruses , vol.5 , pp. 67-75
    • Ambrose, C.S.1    Levin, M.J.2    Belshe, R.B.3
  • 6
    • 0442323299 scopus 로고    scopus 로고
    • Influenza virus: Immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines
    • PMID: 14723616
    • Cox RJ, Brokstad KA, Ogra P Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines. Scand J Immunol 2004;59:1-15; PMID: 14723616; http://dx.doi.org/10.1111/j.0300-9475.2004.01382.x
    • (2004) Scand J Immunol , vol.59 , pp. 1-15
    • Cox, R.J.1    Brokstad, K.A.2    Ogra, P.3
  • 7
    • 79956212139 scopus 로고    scopus 로고
    • Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virus
    • PMID:21600020
    • Harris K, Ream R, Gao J, Eichelberger MC. Intramuscular immunization of mice with live influenza virus is more immunogenic and offers greater protection than immunization with inactivated virus. Virol J 2011;8:251; PMID:21600020; http://dx.doi.org/10.1186/1743-422X-8-251
    • (2011) Virol J , vol.8 , pp. 251
    • Harris, K.1    Ream, R.2    Gao, J.3    Eichelberger, M.C.4
  • 8
    • 0021186924 scopus 로고
    • A one-year study of trivalent influenza vaccines in primed and unprimed volunteers: Immunogenicity, clinical reactions and protection
    • PMID:6736638
    • Masurel N, Laufer J. A one-year study of trivalent influenza vaccines in primed and unprimed volunteers: immunogenicity, clinical reactions and protection. J Hyg (Lond) 1984;92:263-76; PMID:6736638; http://dx.doi.org/10. 1017/S0022172400064500
    • (1984) J Hyg (Lond) , vol.92 , pp. 263-276
    • Masurel, N.1    Laufer, J.2
  • 9
    • 0022868418 scopus 로고
    • Influenza vaccine: The effects of the 1986/1987 viral strains
    • PMID:3552460
    • Ward AE, Hareus AW, Bryett KA, Moore RA. Influenza vaccine: the effects of the 1986/1987 viral strains. Curr Med Res Opin 1987;10:414-21; PMID:3552460; http://dx.doi.org/10.1185/03007998709111111
    • (1987) Curr Med Res Opin , vol.10 , pp. 414-421
    • Ward, A.E.1    Hareus, A.W.2    Bryett, K.A.3    Moore, R.A.4
  • 10
    • 0026604014 scopus 로고
    • Immunogenicity of inactivated influenza vaccine in residential homes for elderly people
    • PMID: 1615780
    • Nicholson KG, Baker DJ, Chakraverty P, Farquhar A, Hurd D, Kent J, et al. Immunogenicity of inactivated influenza vaccine in residential homes for elderly people. Age Ageing 1992;21:182-8; PMID: 1615780; http://dx.doi.org/10. 1093/ageing/21.3.182
    • (1992) Age Ageing , vol.21 , pp. 182-188
    • Nicholson, K.G.1    Baker, D.J.2    Chakraverty, P.3    Farquhar, A.4    Hurd, D.5    Kent, J.6
  • 11
    • 0027406275 scopus 로고
    • Genetic and antigenic analyses of influenza A (H1N1) viruses, 1986-1991
    • PMID:8493812
    • Xu X, Rocha EP, Regenery HL, Kendal AP, Cox NJ. Genetic and antigenic analyses of influenza A (H1N1) viruses, 1986-1991. Virus Res 1993;28:37-55; PMID:8493812; http://dx.doi.org/10.1016/0168-1702 (93) 90088-5
    • (1993) Virus Res , vol.28 , pp. 37-55
    • Xu, X.1    Rocha, E.P.2    Regenery, H.L.3    Kendal, A.P.4    Cox, N.J.5
  • 12
    • 0031925541 scopus 로고    scopus 로고
    • Safety and immunogenicity of low and high doses of trivalent live cold-adapted influenza vaccine administered intranasally as drops or spray to healthy children
    • PMID:9593032
    • King JC Jr., Lagos R, Bernstein DI, Piedra PA, Kotloff K, Bryant M, et al. Safety and immunogenicity of low and high doses of trivalent live cold-adapted influenza vaccine administered intranasally as drops or spray to healthy children. J Infect Dis 1998;177:1394-7; PMID:9593032; http://dx.doi.org/10.1086/517822
    • (1998) J Infect Dis , vol.177 , pp. 1394-1397
    • King Jr., J.C.1    Lagos, R.2    Bernstein, D.I.3    Piedra, P.A.4    Kotloff, K.5    Bryant, M.6
  • 13
    • 0037424114 scopus 로고    scopus 로고
    • Safety and immunogenicity of a liveattenuated influenza vaccine blended and filled at two manufacturing facilities
    • PMID: 12559802
    • Nolan T, Lee MS, Cordova JM, Cho I, Walker RE, August MJ, et al. Safety and immunogenicity of a liveattenuated influenza vaccine blended and filled at two manufacturing facilities. Vaccine 2003;21:1224-31; PMID: 12559802; http://dx.doi.org/10.1016/S0264-410X (02) 00484-X
    • (2003) Vaccine , vol.21 , pp. 1224-1231
    • Nolan, T.1    Lee, M.S.2    Cordova, J.M.3    Cho, I.4    Walker, R.E.5    August, M.J.6
  • 14
    • 0035879705 scopus 로고    scopus 로고
    • Influenza revaccination of elderly travelers: Antibody response to single influenza vaccination and revaccination at 12 weeks
    • PMID:11424016
    • Buxton JA, Skowronski DM, Ng H, Marion SA, Li Y, King A, et al. Influenza revaccination of elderly travelers: antibody response to single influenza vaccination and revaccination at 12 weeks. J Infect Dis 2001;184:188-91; PMID:11424016; http://dx.doi.org/10.1086/322013
    • (2001) J Infect Dis , vol.184 , pp. 188-191
    • Buxton, J.A.1    Skowronski, D.M.2    Ng, H.3    Marion, S.A.4    Li, Y.5    King, A.6
  • 15
    • 0035918179 scopus 로고    scopus 로고
    • Advisory Committee on Immunization Practices. Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP)
    • PMID:11334444
    • Bridges CB, Fukuda K, Cox NJ, Singleton J A; Advisory Committee on Immunization Practices. Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2001;50(RR-4):1-44; PMID:11334444
    • (2001) MMWR Recomm Rep , vol.50 , Issue.RR4 , pp. 1-44
    • Bridges, C.B.1    Fukuda, K.2    Cox, N.J.3    Singleton, J.A.4
  • 16
    • 54549122371 scopus 로고    scopus 로고
    • National Influenza Surveillance Scheme. Annual report of the National Influenza Surveillance Scheme, 2007
    • PMID:18767420
    • Owen R, Barr IG, Pengilley A, Liu C, Paterson B, Kaczmarek M; National Influenza Surveillance Scheme. Annual report of the National Influenza Surveillance Scheme, 2007. Commun Dis Intell QRep 2008;32:208-26; PMID:18767420
    • (2008) Commun Dis Intell QRep , vol.32 , pp. 208-226
    • Owen, R.1    Barr, I.G.2    Pengilley, A.3    Liu, C.4    Paterson, B.5    Kaczmarek, M.6
  • 17
    • 77958195467 scopus 로고    scopus 로고
    • An influenza B outbreak during the 2007/2008 winter among appropriately immunized elderly people living in a nursing home
    • PMID:20846530
    • Camilloni B, Neri M, Lepri E, Basileo M, Sigismondi N, Puzelli S, et al. An influenza B outbreak during the 2007/2008 winter among appropriately immunized elderly people living in a nursing home. Vaccine 2010;28:7536-41; PMID:20846530; http://dx.doi.org/10.1016/j.vaccine.2010.08.064
    • (2010) Vaccine , vol.28 , pp. 7536-7541
    • Camilloni, B.1    Neri, M.2    Lepri, E.3    Basileo, M.4    Sigismondi, N.5    Puzelli, S.6
  • 18
    • 77954326171 scopus 로고    scopus 로고
    • Course of seasonal influenza A/Brisbane/5 9/07 H1N1 infection in the ferret
    • PMID:20618974
    • McBrayer A, Camp JV, Tapp R, Yamshchikov V, Grimes S, Noah DL, et al. Course of seasonal influenza A/Brisbane/5 9/07 H1N1 infection in the ferret. Virol J 2010;7:149; PMID:20618974; http://dx.doi.org/10.1186/1743-422X-7-149
    • (2010) Virol J , vol.7 , pp. 149
    • McBrayer, A.1    Camp, J.V.2    Tapp, R.3    Yamshchikov, V.4    Grimes, S.5    Noah, D.L.6
  • 19
    • 72849150175 scopus 로고    scopus 로고
    • Generation of live attenuated novel influenza virus A/California/7/09 (H1N1) vaccines with high yield in embryonated chicken eggs
    • PMID: 19864389
    • Chen Z, Wang W, Zhou H, Suguitan AL Jr., Shambaugh C, Kim L, et al. Generation of live attenuated novel influenza virus A/California/7/09 (H1N1) vaccines with high yield in embryonated chicken eggs. J Virol 2010;84:44-51; PMID: 19864389; http://dx.doi.org/10.1128/JVI. 02106-09
    • (2010) J Virol , vol.84 , pp. 44-51
    • Chen, Z.1    Wang, W.2    Zhou, H.3    Suguitan Jr., A.L.4    Shambaugh, C.5    Kim, L.6
  • 20
    • 33751243362 scopus 로고    scopus 로고
    • Hemagglutinin (HA) proteins from H1 and H3 serotypes of influenza A viruses require different antigen designs for the induction of optimal protective antibody responses as studied by codon-optimized HA DNA vaccines
    • PMID: 16987975
    • Wang S, Taaffe J, Parker C, Solórzano A, Cao H, Garcfa-Sastre A, et al. Hemagglutinin (HA) proteins from H1 and H3 serotypes of influenza A viruses require different antigen designs for the induction of optimal protective antibody responses as studied by codon-optimized HA DNA vaccines. J Virol 2006;80:11628-37; PMID: 16987975; http://dx.doi.org/10.1128/JVI. 01065-06
    • (2006) J Virol , vol.80 , pp. 11628-11637
    • Wang, S.1    Taaffe, J.2    Parker, C.3    Solórzano, A.4    Cao, H.5    Garcfa-Sastre, A.6
  • 21
    • 0020416123 scopus 로고
    • The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype)
    • PMID:6186384
    • Caton AJ, Brownlee GG, Yewdell JW, Gerhard W. The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype). Cell 1982;31:417-27; PMID:6186384; http://dx.doi.org/10.1016/0092-8674 (82) 90135-0
    • (1982) Cell , vol.31 , pp. 417-427
    • Caton, A.J.1    Brownlee, G.G.2    Yewdell, J.W.3    Gerhard, W.4
  • 22
    • 0019981550 scopus 로고
    • Enumeration of antigenic sites of influenza virus hemagglutinin
    • PMID:6182104
    • Jackson DC, Murray JM, White DO, Gerhard WU. Enumeration of antigenic sites of influenza virus hemagglutinin. Infect Immun 1982;37:912-8; PMID:6182104
    • (1982) Infect Immun , vol.37 , pp. 912-918
    • Jackson, D.C.1    Murray, J.M.2    White, D.O.3    Gerhard, W.U.4
  • 23
    • 0020044535 scopus 로고
    • Conformational changes at topologically distinct antigenic sites on the influenza A/PR/8/34 virus HA molecule are induced by the binding of monoclonal antibodies
    • PMID:6177092
    • Lubeck M, Gerhard W. Conformational changes at topologically distinct antigenic sites on the influenza A/PR/8/34 virus HA molecule are induced by the binding of monoclonal antibodies. Virology 1982;118:1-7; PMID:6177092; http://dx.doi.org/10.1016/0042-6822 (82) 90313-0
    • (1982) Virology , vol.118 , pp. 1-7
    • Lubeck, M.1    Gerhard, W.2
  • 24
    • 0036308877 scopus 로고    scopus 로고
    • Influenza vaccines: Present and future
    • PMID: 12093881
    • Palese P, Garcfa-Sastre A. Influenza vaccines: present and future. J Clin Invest 2002;110:9-13; PMID: 12093881
    • (2002) J Clin Invest , vol.110 , pp. 9-13
    • Palese, P.1    Garcfa-Sastre, A.2
  • 25
    • 70349873173 scopus 로고    scopus 로고
    • Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus
    • PMID:19745214
    • Hancock K, Veguilla V, Lu X, Zhong W, Butler EN, Sun H, et al. Cross-reactive antibody responses to the 2009 pandemic H1N1 influenza virus. N Engl J Med 2009;361:1945-52; PMID:19745214; http://dx.doi.org/10.1056/ NEJMoa0906453
    • (2009) N Engl J Med , vol.361 , pp. 1945-1952
    • Hancock, K.1    Veguilla, V.2    Lu, X.3    Zhong, W.4    Butler, E.N.5    Sun, H.6
  • 26
    • 77951165843 scopus 로고    scopus 로고
    • Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus
    • PMID:20339031
    • Xu R, Ekiert DC, Krause JC, Hai R, Crowe JE Jr., Wilson I A. Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science 2010;328:357-60; PMID:20339031; http://dx.doi.org/10.1126/science. 1186430
    • (2010) Science , vol.328 , pp. 357-360
    • Xu, R.1    Ekiert, D.C.2    Krause, J.C.3    Hai, R.4    Crowe Jr., J.E.5    Wilson, I.A.6
  • 27
    • 45049083212 scopus 로고    scopus 로고
    • Heterologous HA DNA vaccine prime-inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 or H3 serotype influenza viruses
    • PMID: 18538900
    • Wang S, Parker C, Taaffe J, Solórzano A, Garcfa-Sastre A, Lu S. Heterologous HA DNA vaccine prime-inactivated influenza vaccine boost is more effective than using DNA or inactivated vaccine alone in eliciting antibody responses against H1 or H3 serotype influenza viruses. Vaccine 2008;26:3626-33; PMID: 18538900; http://dx.doi.org/10.1016Zj.vaccine.2008.04.073
    • (2008) Vaccine , vol.26 , pp. 3626-3633
    • Wang, S.1    Parker, C.2    Taaffe, J.3    Solórzano, A.4    Garcfa-Sastre, A.5    Lu, S.6
  • 29
    • 31344448218 scopus 로고    scopus 로고
    • Influenza pandemics of the 20th century
    • PMID: 16494710
    • Kilbourne ED. Influenza pandemics of the 20th century. Emerg Infect Dis 2006;12:9-14; PMID: 16494710; http://dx.doi.org/10.3201/eid1201.051254
    • (2006) Emerg Infect Dis , vol.12 , pp. 9-14
    • Kilbourne, E.D.1
  • 30
    • 79952140653 scopus 로고    scopus 로고
    • Influenza virus vaccine based on the conserved hemagglutinin stalk domain
    • PMID:20689752
    • Steel J, Lowen AC, Wang TT, Yondola M, Gao Q, Haye K, et al. Influenza virus vaccine based on the conserved hemagglutinin stalk domain. MBio 2010;1:e00018-10; PMID:20689752; http://dx.doi.org/10.1128ZmBio.00018-10
    • (2010) MBio , vol.1
    • Steel, J.1    Lowen, A.C.2    Wang, T.T.3    Yondola, M.4    Gao, Q.5    Haye, K.6
  • 31
    • 80455168614 scopus 로고    scopus 로고
    • Why do influenza virus subtypes die out? A hypothesis
    • PMID:21878571
    • Palese P, Wang TT. Why do influenza virus subtypes die out? A hypothesis. MBio 2011;2:e00150-11; PMID:21878571; http://dx.doi.org/10.1128/mBio.00150-11
    • (2011) MBio , vol.2
    • Palese, P.1    Wang, T.T.2
  • 32
    • 84872924387 scopus 로고    scopus 로고
    • 1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans
    • PMID:23087428
    • Miller MS, Tsibane T, Krammer F, Hai R, Rahmat S, Basler CF, et al. 1976 and 2009 H1N1 influenza virus vaccines boost anti-hemagglutinin stalk antibodies in humans. J Infect Dis 2013;207:98-105; PMID:23087428; http://dx.doi.org/10. 1093/infdis/jis652
    • (2013) J Infect Dis , vol.207 , pp. 98-105
    • Miller, M.S.1    Tsibane, T.2    Krammer, F.3    Hai, R.4    Rahmat, S.5    Basler, C.F.6
  • 33
    • 77956119219 scopus 로고    scopus 로고
    • Induction of broadly neutralizing H1N1 influenza antibodies by vaccination
    • PMID:20647428
    • Wei CJ, Boyington JC, McTamney PM, Kong WP, Pearce MB, Xu L, et al. Induction of broadly neutralizing H1N1 influenza antibodies by vaccination. Science 2010;329:1060-4; PMID:20647428; http://dx.doi.org/10.1126/science. 1192517
    • (2010) Science , vol.329 , pp. 1060-1064
    • Wei, C.J.1    Boyington, J.C.2    McTamney, P.M.3    Kong, W.P.4    Pearce, M.B.5    Xu, L.6
  • 34
    • 84876791705 scopus 로고    scopus 로고
    • Cross-reactive humoral responses to influenza and their implications for a universal vaccine
    • PMID:23405860
    • Chiu C, Wrammert J, Li GM, McCausland M, Wilson PC, Ahmed R. Cross-reactive humoral responses to influenza and their implications for a universal vaccine. Ann N Y Acad Sci 2013;1283:13-21; PMID:23405860; http://dx.doi.org/10.1111/nyas.12012
    • (2013) Ann N Y Acad Sci , vol.1283 , pp. 13-21
    • Chiu, C.1    Wrammert, J.2    Li, G.M.3    McCausland, M.4    Wilson, P.C.5    Ahmed, R.6
  • 35
    • 33646840487 scopus 로고    scopus 로고
    • Relative contributions of codon usage, promoter efficiency and leader sequence to the antigen expression and immunogenicity of HIV-1 Env DNA vaccine
    • PMID: 16140431
    • Wang S, Farfan-Arribas DJ, Shen S, Chou TH, Hirsch A, He F, et al. Relative contributions of codon usage, promoter efficiency and leader sequence to the antigen expression and immunogenicity of HIV-1 Env DNA vaccine. Vaccine 2006;24:4531-40; PMID: 16140431; http://dx.doi.org/10.1016/j.vaccine.2005.08.023
    • (2006) Vaccine , vol.24 , pp. 4531-4540
    • Wang, S.1    Farfan-Arribas, D.J.2    Shen, S.3    Chou, T.H.4    Hirsch, A.5    He, F.6
  • 36
    • 33746651142 scopus 로고    scopus 로고
    • Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E
    • PMID:16616287
    • Wang S, Pal R, Mascola JR, Chou TH, Mboudjeka I, Shen S, et al. Polyvalent HIV-1 Env vaccine formulations delivered by the DNA priming plus protein boosting approach are effective in generating neutralizing antibodies against primary human immunodeficiency virus type 1 isolates from subtypes A, B, C, D and E. Virology 2006;350:34-47; PMID:16616287; http://dx.doi.org/10.1016/ j.virol.2006.02.032
    • (2006) Virology , vol.350 , pp. 34-47
    • Wang, S.1    Pal, R.2    Mascola, J.R.3    Chou, T.H.4    Mboudjeka, I.5    Shen, S.6
  • 37
    • 41549123253 scopus 로고    scopus 로고
    • The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods
    • PMID: 18378365
    • Wang S, Zhang C, Zhang L, Li J, Huang Z, Lu S. The relative immunogenicity of DNA vaccines delivered by the intramuscular needle injection, electroporation and gene gun methods. Vaccine 2008;26:2100-10; PMID: 18378365; http://dx.doi.org/10.1016/j.vaccine.2008.02.033
    • (2008) Vaccine , vol.26 , pp. 2100-2110
    • Wang, S.1    Zhang, C.2    Zhang, L.3    Li, J.4    Huang, Z.5    Lu, S.6
  • 38
    • 47749129289 scopus 로고    scopus 로고
    • Improved induction of antibodies against key neutralizing epitopes by human immunodeficiency virus type 1 gpl20 DNA prime-protein boost vaccination compared to gpl20 protein-only vaccination
    • PMID:18495775
    • Vaine M, Wang S, Crooks ET, Jiang P, Montefiori DC, Binley J, et al. Improved induction of antibodies against key neutralizing epitopes by human immunodeficiency virus type 1 gpl20 DNA prime-protein boost vaccination compared to gpl20 protein-only vaccination. J Virol 2008;82:7369-78; PMID:18495775; http://dx.doi.org/1 0.1128/JVI.00562-08
    • (2008) J Virol , vol.82 , pp. 7369-7378
    • Vaine, M.1    Wang, S.2    Crooks, E.T.3    Jiang, P.4    Montefiori, D.C.5    Binley, J.6
  • 39
    • 83755225209 scopus 로고    scopus 로고
    • Polyvalent DNA vaccines expressing HA antigens of H5N1 influenza viruses with an optimized leader sequence elicit cross-protective antibody responses
    • PMID:22205966
    • Wang S, Hackett A, Jia N, Zhang C, Zhang L, Parker C, et al. Polyvalent DNA vaccines expressing HA antigens of H5N1 influenza viruses with an optimized leader sequence elicit cross-protective antibody responses. PLoS One 2011;6:e28757; PMID:22205966; http://dx.doi.org/10.1371/journal. pone.0028757
    • (2011) PLoS One , vol.6
    • Wang, S.1    Hackett, A.2    Jia, N.3    Zhang, C.4    Zhang, L.5    Parker, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.