Generation of toxic degradation products by sonication of Pluronic® dispersants: Implications for nanotoxicity testing

Nanotoxicology

Volumn 7, Issue 7, 2013, Pages 1272-1281

  Wang, Ruhung ^a   Hughes, Tyler ^a   Beck, Simon ^a   Vakil, Samee ^a   Li, Synyoung ^a   Pantano, Paul ^a   Draper, Rockford K ^a  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Carbon nanotubes; Nanoparticles; Nanotoxicology; Poloxamer; Ultrasound

Indexed keywords

COPOLYMER; DISPERSANT; GLUTATHIONE; MACROGOL; MULTI WALLED NANOTUBE; POLOXAMER; REACTIVE OXYGEN METABOLITE; TOXIC SUBSTANCE;

ANIMAL CELL; ANIMAL CELL CULTURE; AQUEOUS SOLUTION; ARTICLE; CYTOTOXICITY; DETOXIFICATION; LIGHT SCATTERING; MICROSCOPY; NANOTOXICITY TESTING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT; TISSUE CULTURE; TOXICITY TESTING; ULTRASOUND;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; GLUTATHIONE; KIDNEY; MICROSCOPY, PHASE-CONTRAST; NANOTUBES, CARBON; POLOXAMER; RATS; REACTIVE OXYGEN SPECIES; SERUM ALBUMIN, BOVINE; SONICATION; SUSPENSIONS; TOXICITY TESTS;

EID: 84885115367     PISSN: 17435390     EISSN: 17435404     Source Type: Journal    
DOI: 10.3109/17435390.2012.736547     Document Type: Article

References (22)

1. Alexandridis P, Holzwarth JF, Hatton TA. 1994. Micellization of poly (ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymers in aqueous solutions: Thermodynamics of copolymer association. Macromolecules 27:2414-2425.
2. Bahadur P, Li P, Almgren M, Brown W. 1992. Effect of potassium fluoride on the micellar behavior of Pluronic F-68 in aqueous solution. Langmuir 8:1903-1907.
3. Ciofani G, Raffa V, Pensabene V, Menciassi A, Dario P. 2008. Dispersion of multi-walled carbon nanotubes in aqueous Pluronic F127 solutions for biological applications. Fullerenes Nanotubes Carbon Nanostructures 17:11-25.
4. Kawasaki H, Takeda Y, Arakawa R. 2007. Mass spectrometric analysis for high molecular weight synthetic polymers using ultrasonic degradation and the mechanism of degradation. Anal Chem 79:4182-4187.
5. Koda S, Mori H, Matsumoto K, Nomura H. 1994. Ultrasonic degradation of water-soluble polymers. Polymer (Guildf) 35:30-33.
6. Kurfürst MM. 1992. Detection and molecular weight determination of polyethylene glycol-modified hirudin by staining after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem 200:244-248.
7. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
8. Mejia J, Tichelaar F, Saout C, Toussaint O, Masereel B, Mekhalif Z, et al. 2011. Effects of the dispersion methods in Pluronic F108 on the size and the surface composition of MWCNTs and their implications in toxicology assessment. J Nanopart Res 13:655-667.
9. Nascentes CC, Korn M, Sousa CS, Arruda MAZ. 2001. Use of ultrasonic baths for analytical applications: a new approach for optimisation conditions. J Braz Chem Soc 12:57-63.
10. Neppiras EA. 1984. Acoustic cavitation series: part one: Acoustic cavitation: an introduction. Ultrasonics 22:25-28.
11. Singla R, Grieser F, Ashokkumar M. 2009. Kinetics and mechanism for the sonochemical degradation of a nonionic surfactant. J Phys Chem A 113:2865-2872.
12. Sostaric JZ, Riesz P. 2002. Adsorption of surfactants at the gas/solution Interface of cavitation bubbles: an ultrasound intensity-independent frequency effect in sonochemistry. J Phys Chem B 106:12537-12548.
13. Suslick KS. 1990. Sonochemistry. Science 247:1439-1445.
14. Suslick KS, Flannigan DJ. 2008. Inside a collapsing bubble: Sonoluminescence and the conditions during cavitation. Annu Rev Phys Chem 59:659-683.
15. Suslick KS, Price GJ. 1999. Applications of ultrasound to materials chemistry. Annu Rev Mater Sci 29:295-326.
16. Taurozzi JS, Hackley VA, Wiesner MR. 2011. Ultrasonic dispersion of nanoparticles for environmental, health and safety assessment-issues and recommendations. Nanotoxicology 5:711-729.
17. Vijayalakshmi SP, Madras G. 2004. Effect of temperature on the ultrasonic degradation of polyacrylamide and poly(ethylene oxide). Polym Degradat Stab 84:341-344.
18. Vijayalakshmi SP, Madras G. 2005. Effect of initial molecular weight and solvents on the ultrasonic degradation of poly(ethylene oxide). Polym Degradat Stab 90:116-122.
19. Wang R, Mikoryak C, Li S, Bushdiecker D, Musselman IH, Pantano P, et al. 2011. Cytotoxicity screening of single-walled carbon nanotubes: detection and removal of cytotoxic contaminants from carboxylated carbon nanotubes. Mol Pharm 8:1351-1361.
20. Watanabe T, Okabayashi M, Kurokawa D, Nishimoto Y, Ozawa T, Kawasaki H, et al. 2010. Determination of primary bond scissions by mass spectrometric analysis of ultrasonic degradation products of poly(ethylene oxide-block-propylene oxide) copolymers. J Mass Spectrom 45:799-805.
21. Zeineldin R, Al-Haik M, Hudson LG. 2009. Role of polyethylene glycol integrity in specific receptor targeting of carbon nanotubes to cancer cells. Nano Lett 9:751-757.
22. Zhou Z, Chu B. 1988.Light-scattering study on the association behavior of triblock polymers of ethylene oxide and propylene oxide in aqueous solution. J Colloid Interface Sci 126:171-180.