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Volumn 3, Issue , 2013, Pages

Enhancing Cell Nucleus Accumulation and DNA Cleavage Activity of Anti-Cancer Drug via Graphene Quantum Dots

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; GRAPHITE; QUANTUM DOT;

EID: 84885097031     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep02852     Document Type: Article
Times cited : (188)

References (51)
  • 1
    • 84875132279 scopus 로고    scopus 로고
    • Can controversial nanotechnology promise drug delivery?
    • Devadasu, V. R., Bhardwaj, V. & Kumar, M. N. V. R. Can Controversial Nanotechnology Promise Drug Delivery? Chem. Rev. 113, 1686-1735 (2012).
    • (2012) Chem Rev. , vol.113 , pp. 1686-1735
    • Devadasu, V.R.1    Bhardwaj, V.2    Kumar, M.N.V.R.3
  • 2
    • 36849067019 scopus 로고    scopus 로고
    • Nanocarriers as an emerging platform for cancer therapy
    • Peer, D. et al. Nanocarriers as an emerging platform for cancer therapy. Nature Nanotech. 2, 751-760 (2007).
    • (2007) Nature Nanotech. , vol.2 , pp. 751-760
    • Peer, D.1
  • 3
    • 38949105860 scopus 로고    scopus 로고
    • Functionalized carbon nanotubes in drug design and discovery
    • Prato, M., Kostarelos, K. & Bianco, A. Functionalized Carbon Nanotubes in Drug Design and Discovery. Acc. Chem. Res. 41, 60-68 (2007).
    • (2007) Acc. Chem. Res. , vol.41 , pp. 60-68
    • Prato, M.1    Kostarelos, K.2    Bianco, A.3
  • 4
    • 84867377391 scopus 로고    scopus 로고
    • AmPhiPhilic homopolymer vesicles as unique nano-Carriers for cancer therapy
    • Mane, S. R. et al. AmPhiPhilic Homopolymer Vesicles as Unique Nano-Carriers for Cancer Therapy. Macromolecules 45, 8037-8042 (2012).
    • (2012) Macromolecules , vol.45 , pp. 8037-8042
    • Mane, S.R.1
  • 5
    • 78650294585 scopus 로고    scopus 로고
    • Synthesis and characterization of amPhiPhilic glycidol2chitosan2deoxycholic acid nanoparticles as a drug carrier for doxorubicin
    • Zhou, H. et al. Synthesis and Characterization of AmPhiPhilic Glycidol2Chitosan2Deoxycholic Acid Nanoparticles as a Drug Carrier for Doxorubicin. Biomacromolecules 11, 3480-3486 (2010).
    • (2010) Biomacromolecules , vol.11 , pp. 3480-3486
    • Zhou, H.1
  • 6
    • 0037462130 scopus 로고    scopus 로고
    • Multifunctional gold nanoparticle2peptide complexes for nuclear targeting
    • Tkachenko, A. G. et al. Multifunctional Gold Nanoparticle2Peptide Complexes for Nuclear Targeting. J. Am. Chem. Soc. 125, 4700-4701 (2003).
    • (2003) J. Am. Chem. Soc. , vol.125 , pp. 4700-4701
    • Tkachenko, A.G.1
  • 7
    • 84865141619 scopus 로고    scopus 로고
    • Self-Assembled plasmonic vesicles of sers-Encoded amPhiPhilic gold nanoparticles for cancer cell targeting and traceable intracellular drug Delivery
    • Song, J., Zhou, J.&Duan,H. Self-Assembled Plasmonic Vesicles of SERS-Encoded AmPhiPhilic Gold Nanoparticles for Cancer Cell Targeting and Traceable Intracellular Drug Delivery. J. Am. Chem. Soc. 134, 13458-13469 (2012).
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 13458-13469
    • Song, J.1    Zhou, J.2    Duan, H.3
  • 8
    • 54249097231 scopus 로고    scopus 로고
    • Designed fabrication of a multifunctional polymer nanomedical platform for simultaneous cancer-Targeted imaging and magnetically guided drug delivery
    • Kim, J. et al. Designed Fabrication of a Multifunctional Polymer Nanomedical Platform for Simultaneous Cancer-Targeted Imaging and Magnetically Guided Drug Delivery. Adv. Mater. 20, 478-483 (2008).
    • (2008) Adv. Mater. , vol.20 , pp. 478-483
    • Kim, J.1
  • 9
    • 79958792115 scopus 로고    scopus 로고
    • Ph-Triggered controlled drug release from mesoporous silica nanoparticles via intracelluar dissolution of zno nanolids
    • Muhammad, F. et al. Ph-Triggered Controlled Drug Release from Mesoporous Silica Nanoparticles via Intracelluar Dissolution of ZnO Nanolids. J. Am. Chem. Soc. 133, 8778-8781 (2011).
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 8778-8781
    • Muhammad, F.1
  • 10
    • 84867776387 scopus 로고    scopus 로고
    • Dna origamidelivery system for cancer therapy with tunable release properties
    • Zhao, YX. et al.DNA OrigamiDelivery System for Cancer Therapy with Tunable Release Properties. ACS Nano 6, 8684-8691 (2012).
    • (2012) ACS Nano , vol.6 , pp. 8684-8691
    • Zhao, Y.X.1
  • 11
    • 84855430040 scopus 로고    scopus 로고
    • Estrogen-Anchored Ph-Sensitive liposomes as nanomodule designed for site-Specific delivery of doxorubicin in breast cancer therapy
    • Paliwal, S. R. et al. Estrogen-Anchored Ph-Sensitive Liposomes as Nanomodule Designed for Site-Specific Delivery of Doxorubicin in Breast Cancer Therapy. Mol. Pharm. 9, 176-186 (2011).
    • (2011) Mol. Pharm. , vol.9 , pp. 176-186
    • Paliwal, S.R.1
  • 12
    • 84859343412 scopus 로고    scopus 로고
    • Nuclear-Targeted drug delivery of tat peptide-Conjugated monodisperse mesoporous silica nanoparticles
    • Pan, L. et al. Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles. J. Am. Chem. Soc. 134, 5722-5725 (2012).
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 5722-5725
    • Pan, L.1
  • 13
    • 84865998674 scopus 로고    scopus 로고
    • Ph and redox dual responsive nanoparticle for nuclear targeted drug delivery
    • K. C., R. B., Thapa, B. & Xu, P. Ph and Redox Dual Responsive Nanoparticle for Nuclear Targeted Drug Delivery. Mol. Pharm. 9, 2719-2729 (2012).
    • (2012) Mol. Pharm. , vol.9 , pp. 2719-2729
    • Thapa, B.1    Xu, P.2
  • 14
    • 34547690726 scopus 로고    scopus 로고
    • Immunological properties of engineered nanomaterials
    • Dobrovolskaia, M. A. & McNeil, S. E. Immunological properties of engineered nanomaterials. Nature Nanotech. 2, 469-478 (2007).
    • (2007) Nature Nanotech. , vol.2 , pp. 469-478
    • Dobrovolskaia, M.A.1    McNeil, S.E.2
  • 15
    • 84877626083 scopus 로고    scopus 로고
    • GraPhene: Promises, facts, opportunities, and challenges in nanomedicine
    • Mao, H. Y. et al. GraPhene: Promises, Facts, Opportunities, and Challenges in Nanomedicine. Chem. Rev. 113, 3407-3424 (2013).
    • (2013) Chem. Rev. , vol.113 , pp. 3407-3424
    • Mao, H.Y.1
  • 16
    • 79952586310 scopus 로고    scopus 로고
    • GraPhene in biomedicine: Opportunities and challenges
    • Feng, L. & Liu, Z. GraPhene in biomedicine: Opportunities and challenges. Nanomedicine 6, 317-324 (2011).
    • (2011) Nanomedicine , vol.6 , pp. 317-324
    • Feng, L.1    Liu, Z.2
  • 17
    • 84862551518 scopus 로고    scopus 로고
    • GraPhene: A versatile nanoplatform for biomedical applications
    • Zhang, Y., Nayak, T. R., Hong, H. & Cai, W. GraPhene: A versatile nanoplatform for biomedical applications. Nanoscale 4, 3833-3842 (2012).
    • (2012) Nanoscale , vol.4 , pp. 3833-3842
    • Zhang, Y.1    Nayak, T.R.2    Hong, H.3    Cai, W.4
  • 18
    • 53849085330 scopus 로고    scopus 로고
    • Nano-GraPhene oxide for cellular imaging and drug delivery
    • Sun, X. et al. Nano-GraPhene oxide for cellular imaging and drug delivery. Nano Res. 1, 203-212 (2008).
    • (2008) Nano Res. , vol.1 , pp. 203-212
    • Sun, X.1
  • 19
    • 80054038741 scopus 로고    scopus 로고
    • GraPhene oxide noncovalent photosensitizer and its anticancer activity in vitro
    • Zhou, L. et al. GraPhene Oxide Noncovalent Photosensitizer and Its Anticancer Activity In Vitro. Chem. Eur. J. 17, 12084-12091 (2011).
    • (2011) Chem. Eur. J. , vol.17 , pp. 12084-12091
    • Zhou, L.1
  • 20
    • 80052563472 scopus 로고    scopus 로고
    • Folic acid-Conjugated graphene oxide loaded with photosensitizers for targeting photodynamic therapy
    • Huang, P. et al. Folic Acid-Conjugated GraPhene Oxide loaded with Photosensitizers for Targeting Photodynamic Therapy. Theranostics 1, 240-250 (2011).
    • (2011) Theranostics , vol.1 , pp. 240-250
    • Huang, P.1
  • 21
    • 79951938481 scopus 로고    scopus 로고
    • Multi-Functionalized graPhene oxide based anticancer drug-Carrier with dual-Targeting function and Ph-Sensitivity
    • Yang, X. et al.Multi-Functionalized graPhene oxide based anticancer drug-Carrier with dual-Targeting function and Ph-Sensitivity. J. Mater. Chem. 21, 3448-3454 (2011).
    • (2011) J. Mater. Chem. , vol.21 , pp. 3448-3454
    • Yang, X.1
  • 22
    • 77956455985 scopus 로고    scopus 로고
    • Graphene in mice: Ultrahigh in vivo tumor uptake and efficient photothermal therapy
    • Yang, K. et al. GraPhene in Mice: Ultrahigh In Vivo Tumor Uptake and Efficient Photothermal Therapy. Nano Lett. 10, 3318-3323 (2010).
    • (2010) Nano Lett. , vol.10 , pp. 3318-3323
    • Yang, K.1
  • 23
    • 50249123111 scopus 로고    scopus 로고
    • PEgylated nanographene oxide for delivery of water-insoluble cancer drugs
    • Liu, Z., Robinson, J. T., Sun, X. & Dai, H. PEGylated NanograPhene Oxide for Delivery of Water-Insoluble Cancer Drugs. J. Am. Chem. Soc. 130, 10876-10877 (2008).
    • (2008) J. Am. Chem. Soc. , vol.130 , pp. 10876-10877
    • Liu, Z.1    Robinson, J.T.2    Sun, X.3    Dai, H.4
  • 24
    • 77649121111 scopus 로고    scopus 로고
    • Functional graphene oxide as a nanocarrier for controlled loading and targeted delivery of mixed anticancer drugs
    • Zhang, L., Xia, J., Zhao, Q., Liu, L. & Zhang, Z. Functional GraPhene Oxide as a Nanocarrier for Controlled Loading and Targeted Delivery of Mixed Anticancer Drugs. Small 6, 537-544 (2010).
    • (2010) Small , vol.6 , pp. 537-544
    • Zhang, L.1    Xia, J.2    Zhao, Q.3    Liu, L.4    Zhang, Z.5
  • 25
    • 78650730366 scopus 로고    scopus 로고
    • DNA Cleavage system of nanosized graphene oxide sheets and copper ions
    • Ren, H. et al. DNA Cleavage System of Nanosized GraPhene Oxide Sheets and Copper Ions. ACS Nano 4, 7169-7174 (2010).
    • (2010) ACS Nano , vol.4 , pp. 7169-7174
    • Ren, H.1
  • 26
    • 84864213687 scopus 로고    scopus 로고
    • Nuclease activity and cytotoxicity enhancement of the dna intercalators via graphene oxide
    • Zheng, B. et al. Nuclease Activity and Cytotoxicity Enhancement of the DNA Intercalators via GraPhene Oxide. J. Phys. Chem. C 116, 15839-15846 (2012).
    • (2012) J. Phys. Chem. C , vol.116 , pp. 15839-15846
    • Zheng, B.1
  • 27
    • 84865576277 scopus 로고    scopus 로고
    • Photo-Fenton reaction of graphene oxide: A new strategy to prepare graphene quantum dots for dna cleavage
    • Zhou, X. et al. Photo-Fenton Reaction of GraPhene Oxide: A New Strategy to Prepare GraPhene Quantum Dots for DNA Cleavage. ACS Nano 6, 6592-6599 (2012).
    • (2012) ACS Nano , vol.6 , pp. 6592-6599
    • Zhou, X.1
  • 29
    • 0016647722 scopus 로고
    • Adriamycin-A review
    • Carter, S. K. Adriamycin-A Review. J. Natl. Cancer Inst. 55, 1263-1263 (1975).
    • (1975) J. Natl. Cancer Inst. , vol.55 , pp. 1263-1263
    • Carter, S.K.1
  • 30
    • 33646394582 scopus 로고    scopus 로고
    • Doxorubicin-Dna adducts induce a non-Topoisomerase ii-Mediated form of cell death
    • Swift, L. P., RePhaeli, A.,Nudelman, A., Phillips, D. R.&Cutts, S. M. Doxorubicin-DNA Adducts Induce a Non-Topoisomerase II-Mediated Form of Cell Death. Cancer Res. 66, 4863-4871 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 4863-4871
    • Swift, L.P.1    Rephaeli, A.2    Nudelman, A.3    Phillips, D.R.4    Cutts, S.M.5
  • 31
    • 0027751822 scopus 로고
    • Dependence of nucleic acid degradation on in situ free-Radical production by adriamycin
    • Feinstein, E., Canaani, E. & Weiner, L. M. Dependence of Nucleic Acid Degradation on in situ Free-Radical Production by Adriamycin. Biochemistry 32, 13156-13161 (1993).
    • (1993) Biochemistry , vol.32 , pp. 13156-13161
    • Feinstein, E.1    Canaani, E.2    Weiner, L.M.3
  • 32
    • 0017646174 scopus 로고
    • Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents
    • William Lown, J., Sim, S. K., Majumdar, K. C. & Chang, R. Y. Strand scission of DNA by bound adriamycin and daunorubicin in the presence of reducing agents. Biochem. BioPhys. Res. Commun. 76, 705-710 (1977).
    • (1977) Biochem. BioPhys. Res. Commun. , vol.76 , pp. 705-710
    • William Lown, J.1    Sim, S.K.2    Majumdar, K.C.3    Chang, R.Y.4
  • 33
    • 0001764525 scopus 로고
    • Determining binding constants of metal complexes to dna by quenching of the emission of pt2(pop)44-(pop 5 P2O5H22-)
    • Kalsbeck, W. A. & Thorp, H. H. Determining Binding Constants of Metal Complexes to DNA by Quenching of the Emission of Pt2(pop)44-(pop 5 P2O5H22-). J. Am. Chem. Soc. 115, 7146-7151 (1993).
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 7146-7151
    • Kalsbeck, W.A.1    Thorp, H.H.2
  • 34
    • 36849063744 scopus 로고    scopus 로고
    • Supramolecular chemistry on water-Soluble carbon nanotubes for drug loading and delivery
    • Liu, Z., Sun, X., Nakayama-Ratchford, N. &Dai, H. Supramolecular Chemistry on Water-Soluble Carbon Nanotubes for Drug Loading and Delivery. ACS Nano 1, 50-56 (2007).
    • (2007) ACS Nano , vol.1 , pp. 50-56
    • Liu, Z.1    Sun, X.2    Nakayama-Ratchford, N.3    Dai, H.4
  • 35
    • 57049151286 scopus 로고    scopus 로고
    • High-Efficiency loading and controlled release of doxorubicin hydrochloride on graphene oxide
    • Yang, X. et al. High-Efficiency Loading and Controlled Release of Doxorubicin Hydrochloride on GraPhene Oxide. J. Phys. Chem. C 112, 17554-17558 (2008).
    • (2008) J. Phys. Chem. C , vol.112 , pp. 17554-17558
    • Yang, X.1
  • 36
    • 0022979405 scopus 로고
    • Single-Strand dna breaks induced by chromophore-Modified anthracyclines in p388 leukemia cells
    • Capranico, G., Soranzo, C. & Zunino, F. Single-Strand DNA Breaks Induced by ChromoPhore-Modified Anthracyclines in P388 Leukemia Cells. Cancer Res. 46, 5499-5503 (1986).
    • (1986) Cancer Res. , vol.46 , pp. 5499-5503
    • Capranico, G.1    Soranzo, C.2    Zunino, F.3
  • 37
    • 0033557922 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin d3 enhances the susceptibility of breast cancer cells to doxorubicin-Induced oxidative damage
    • Ravid, A. et al. 1,25-Dihydroxyvitamin D3 Enhances the Susceptibility of Breast Cancer Cells to Doxorubicin-Induced Oxidative Damage. Cancer Res. 59, 862-867 (1999).
    • (1999) Cancer Res. , vol.59 , pp. 862-867
    • Ravid, A.1
  • 38
    • 84863455559 scopus 로고    scopus 로고
    • Drug-Loaded chondroitin sulfate-Based nanogels: Preparation and characterization
    • Xi, J., Zhou, L. & Dai, H. Drug-Loaded chondroitin sulfate-Based nanogels: Preparation and characterization. Colloids Surf. B Biointerfaces 100, 107-115 (2012).
    • (2012) Colloids Surf. B Biointerfaces , vol.100 , pp. 107-115
    • Xi, J.1    Zhou, L.2    Dai, H.3
  • 39
    • 84885122587 scopus 로고    scopus 로고
    • Cellular internalization and low cytotoxicity of graphene quantum dots
    • 10.1002/adhm.201300066
    • Wu, C. et al. Cellular Internalization and Low Cytotoxicity of GraPhene Quantum Dots. Adv. Healthcare Mater. 10.1002/adhm.201300066 (2013).
    • (2013) Adv. Healthcare Mater.
    • Wu, C.1
  • 40
    • 74849110624 scopus 로고    scopus 로고
    • A novel doxorubicin-Mitomycin C co-Encapsulated nanoparticle formulation exhibits anti-Cancer synergy in multidrug resistant human breast cancer cells
    • Shuhendler, A. et al. A novel doxorubicin-Mitomycin C co-Encapsulated nanoparticle formulation exhibits anti-Cancer synergy in multidrug resistant human breast cancer cells. Breast Cancer Res. Treat. 119, 255-269 (2010).
    • (2010) Breast Cancer Res. Treat. , vol.119 , pp. 255-269
    • Shuhendler, A.1
  • 41
    • 77954880957 scopus 로고    scopus 로고
    • Gateways for the intracellular access of nanocarriers: A review of receptor-Mediated endocytosis mechanisms and of strategies in receptor targeting
    • Zaki, N. M. & Tirelli, N. Gateways for the intracellular access of nanocarriers: A review of receptor-Mediated endocytosis mechanisms and of strategies in receptor targeting. Expert Opin. Drug Deliv. 7, 895-913 (2010).
    • (2010) Expert Opin. Drug Deliv. , vol.7 , pp. 895-913
    • Zaki, N.M.1    Tirelli, N.2
  • 42
    • 84860322834 scopus 로고    scopus 로고
    • Size-Dependent cell uptake of protein-Coated graphene oxide nanosheets
    • Mu, Q. et al. Size-Dependent Cell Uptake of Protein-Coated GraPhene Oxide Nanosheets. ACS Appl. Mater. Interfaces 4, 2259-2266 (2012).
    • (2012) ACS Appl. Mater. Interfaces , vol.4 , pp. 2259-2266
    • Mu, Q.1
  • 43
    • 80455168058 scopus 로고    scopus 로고
    • Tailor-Made dual ph-Sensitive polymer-Doxorubicin nanoparticles for efficient anticancer drug delivery
    • Du, J. Z., Du, X. J., Mao, C. Q. & Wang, J. Tailor-Made Dual Ph-Sensitive Polymer-Doxorubicin Nanoparticles for Efficient Anticancer Drug Delivery. J. Am. Chem. Soc. 133, 17560-17563 (2011).
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 17560-17563
    • Du, J.Z.1    Du, X.J.2    Mao, C.Q.3    Wang, J.4
  • 44
    • 79961162541 scopus 로고    scopus 로고
    • Catechol polymers for phresponsive, targeted drug delivery to cancer cells
    • Su, J., Chen, F., Cryns, V. L. & Messersmith, P. B. Catechol Polymers for PhResponsive, Targeted Drug Delivery to Cancer Cells. J. Am. Chem. Soc. 133, 11850-11853 (2011).
    • (2011) J. Am. Chem. Soc. , vol.133 , pp. 11850-11853
    • Su, J.1    Chen, F.2    Cryns, V.L.3    Messersmith, P.B.4
  • 45
    • 0016652057 scopus 로고
    • Nuclear envelope permeability
    • Paine, P. L.,Moore, L. C. &Horowitz, S. B. Nuclear envelope permeability. Nature 254, 109-114 (1975).
    • (1975) Nature , vol.254 , pp. 109-114
    • Paine, P.L.1    Moore, L.C.2    Horowitz, S.B.3
  • 46
    • 0033764455 scopus 로고    scopus 로고
    • Supramolecular structure and nuclear targeting efficiency determine the enhancement of transfection by modifed polylysines
    • Chan, C. K. & Jans, D. A. Supramolecular structure and nuclear targeting efficiency determine the enhancement of transfection by modifed polylysines. Gene Ther. 7, 1690-1697 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 1690-1697
    • Chan, C.K.1    Jans, D.A.2
  • 47
    • 0033942026 scopus 로고    scopus 로고
    • Toxicity and dna binding of dextran-Doxorubicin conjugates in multidrug-Resistant kb-V1 cells: Pptimization of dextran size
    • Lam, W., Leung, C. H., Chan, H. L. & Fong, W. F. Toxicity and DNA binding of dextran-Doxorubicin conjugates in multidrug-Resistant KB-V1 cells: Optimization of dextran size. Anti-Cancer Drug 11, 377-384 (2000).
    • (2000) Anti-Cancer Drug , vol.11 , pp. 377-384
    • Lam, W.1    Leung, C.H.2    Chan, H.L.3    Fong, W.F.4
  • 48
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-Dependent transporters
    • Gottesman, M. M., Fojo, T. & Bates, S. E. Multidrug resistance in cancer: Role of ATP-Dependent transporters. Nat. Rev. Cancer 2, 48-58 (2002).
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 49
    • 0036176510 scopus 로고    scopus 로고
    • Mechanism of cancer drug resistance
    • Gottesman, M. M. Mechanism Of Cancer Drug Resistance. Annu. Rev. Med. 53, 615-627 (2002).
    • (2002) Annu. Rev. Med. , vol.53 , pp. 615-627
    • Gottesman, M.M.1
  • 50
    • 84865121664 scopus 로고    scopus 로고
    • DNA Origami as a carrier for circumvention of drug resistance
    • Jiang, Q. et al. DNA Origami as a Carrier for Circumvention of Drug Resistance. J. Am. Chem. Soc. 134, 13396-13403 (2012).
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 13396-13403
    • Jiang, Q.1
  • 51
    • 77954599597 scopus 로고    scopus 로고
    • Multifunctional nanoparticles delivering small interfering rnaand doxorubicin overcomedrug resistance in cancer
    • Chen, Y., Bathula, S. R., Li, J. & Huang, L. Multifunctional Nanoparticles Delivering Small Interfering RNAand Doxorubicin OvercomeDrug Resistance in Cancer. J. Biol. Chem. 285, 22639-22650 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 22639-22650
    • Chen, Y.1    Bathula, S.R.2    Li, J.3    Huang, L.4


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