The ATP costs and time required to degrade ubiquitinated proteins by the 26 S proteasome

Journal of Biological Chemistry

Volumn 288, Issue 40, 2013, Pages 29215-29222

  Peth, Andreas ^a   Nathan, James A ^b   Goldberg, Alfred L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

26 S PROTEASOME; ATP HYDROLYSIS; PROTEASOMES; UBIQUITIN; UBIQUITINATED PROTEINS;

BIOCHEMISTRY; BIOLOGY;

PROTEINS;

26 S PROTEASOME; ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; DIHYDROFOLATE REDUCTASE; FOLIC ACID; FUNGAL PROTEIN; MUTANT PROTEIN; POLYPEPTIDE; PROTEASOME; PROTEIN RPT3; PROTEIN RPT5; PROTEIN RPT6; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENERGY EXPENDITURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE MUTATION; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; UBIQUITINATION;

26 S PROTEASOME; AAA-ATPASES; ATP; ATP HYDROLYSIS; ATPASES; PROTEASOME; PROTEIN DEGRADATION; UBIQUITIN; UBIQUITIN CONJUGATES;

ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; ANIMALS; HYDROLYSIS; KINETICS; MICE; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN SUBUNITS; PROTEOLYSIS; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY; THERMODYNAMICS; TIME FACTORS; UBIQUITINATED PROTEINS;

EID: 84885094614     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.482570     Document Type: Article

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