Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

PLoS Pathogens

Volumn 9, Issue 10, 2013, Pages

  Matreyek, Kenneth A ^a   Yücel, Sara S ^a   Li, Xiang ^a   Engelman, Alan ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CAPSID PROTEIN; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; GLYCINE; GREEN FLUORESCENT PROTEIN; MUTANT PROTEIN; NITRILOTRIACETATE NICKEL; NUCLEOPORIN; NUCLEOPORIN 153; PF 3450074; PHENYLALANINE; TRIPARTITE MOTIF PROTEIN 5; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELL CYCLE; CRYSTAL STRUCTURE; EQUINE INFECTIOUS ANEMIA VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOFLUORESCENCE MICROSCOPY; LENTIVIRUS INFECTION; MURINE LEUKEMIA VIRUS; MUTAGENESIS; NONHUMAN; OSTEOSARCOMA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN MOTIF; PROTEIN PURIFICATION; RETROVIRUS INFECTION; VIRUS CAPSID; WESTERN BLOTTING;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID MOTIFS; BINDING SITES; CELL CYCLE; CELL LINE; CELL NUCLEUS; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV INFECTIONS; HIV-1; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MRNA CLEAVAGE AND POLYADENYLATION FACTORS; MUTATION; NUCLEAR PORE COMPLEX PROTEINS; PROTEIN BINDING;

EID: 84885090088     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003693     Document Type: Article

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