The Upf factor complex interacts with aberrant products derived from mrnas containing a premature termination codon and facilitates their proteasomal degradation

Journal of Biological Chemistry

Volumn 288, Issue 40, 2013, Pages 28630-28640

  Kuroha, Kazushige ^a   Ando, Koji ^a   Nakagawa, Reiko ^b   Inada, Toshifumi ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b RIKEN Center for Biosystems Dynamics Research   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FRAMESHIFT; PREMATURE TERMINATION CODON; PROTEASOMAL DEGRADATION; UNFOLDED PROTEINS;

BIOCHEMISTRY;

BIOLOGY;

HEAT SHOCK PROTEIN 70; MESSENGER RNA; PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; UP FRAMESHIFT PROTEIN 1; VON HIPPEL LINDAU PROTEIN;

3' UNTRANSLATED REGION; ARTICLE; CODON; CONTROLLED STUDY; MASS SPECTROMETRY; NONHUMAN; PREMATURE TERMINATION CODON; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; PROTEIN UNFOLDING; SACCHAROMYCES CEREVISIAE; UBIQUITINATION; WESTERN BLOTTING;

GENE REGULATION; MRNA DECAY; PROTEIN FOLDING; PROTEIN TURNOVER; RIBOSOMES;

3' UNTRANSLATED REGIONS; CODON, NONSENSE; HEK293 CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MODELS, BIOLOGICAL; MULTIPROTEIN COMPLEXES; PHOSPHOGLYCERATE KINASE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN UNFOLDING; PROTEOLYSIS; RNA, FUNGAL; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITINATION; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84885087029     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.460691     Document Type: Article

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