Molecular Marker Differences Relate to Developmental Position and Subsets of Mesodiencephalic Dopaminergic Neurons

PLoS ONE

Volumn 8, Issue 10, 2013, Pages

  Smits, Simone M ^b   von Oerthel, Lars ^a,b   Hoekstra, Elisa J ^a   Burbach, J Peter H ^b   Smidt, Marten P ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLECYSTOKININ; G PROTEIN COUPLED RECEPTOR KINASE 3; PROTEIN HOMER 2; TRANSCRIPTION FACTOR PBX1;

ADRA1B GENE; ADRBK2 GENE; AHD2 GENE; ANIMAL TISSUE; ANTERIOR POSTERIOR AXIS; ARTICLE; CCK GENE; CDH11 GENE; CDH8 GENE; CELL POPULATION; CONTROLLED STUDY; DAT GENE; DIENCEPHALON; DOPAMINERGIC NERVE CELL; DSSCR1L1 GENE; EMBRYO; GENE; GENE EXPRESSION; GENETIC MARKER; GRP GENE; GSG1L1 GENE; HIPK2 GENE; HOMER2 GENE; IN SITU HYBRIDIZATION; MESENCEPHALON; MESODIENCEPHALIC DOPAMINERGIC NEURON; MOUSE; NERVE CELL DIFFERENTIATION; NEURITIN GENE; NEUROMERE; NONHUMAN; NUCLEOTIDE SEQUENCE; PBX1 GENE; PBX3 GENE; RHOMBENCEPHALON; SLC25A5 GENE; SUBSTANTIA NIGRA PARS COMPACTA; VENTRAL TEGMENTUM;

ANIMALS; DOPAMINERGIC NEURONS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; SUBSTANTIA NIGRA; VENTRAL TEGMENTAL AREA;

EID: 84885041593     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076037     Document Type: Article

References (37)

1. Hirsch E, Graybiel AM, Agid YA, (1988) Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature 334: 345-348 doi:10.1038/334345a0.
2. Blum D, Torch S, Lambeng N, Nissou M, Benabid AL, et al. (2001) Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog Neurobiol 65: 135-172.
3. Greene JG, Dingledine R, Greenamyre JT, (2005) Gene expression profiling of rat midbrain dopamine neurons: implications for selective vulnerability in parkinsonism. Neurobiol Dis 18: 19-31 doi:10.1016/j.nbd.2004.10.003.
4. Grimm J, Mueller A, Hefti F, Rosenthal A, (2004) Molecular basis for catecholaminergic neuron diversity. Proc Natl Acad Sci USA 101: 13891-13896 doi:10.1073/pnas.0405340101.
5. Wolfart J, Neuhoff H, Franz O, Roeper J, (2001) Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons. J Neurosci 21: 3443-3456.
6. Neuhoff H, Neu A, Liss B, Roeper J, (2002) I(h) channels contribute to the different functional properties of identified dopaminergic subpopulations in the midbrain. J Neurosci 22: 1290-1302.
7. Jacobs FMJ, Veenvliet JV, Almirza WH, Hoekstra EJ, von Oerthel L, et al. (2011) Retinoic acid-dependent and-independent gene-regulatory pathways of Pitx3 in meso-diencephalic dopaminergic neurons. Development 138: 5213-5222 doi:10.1242/dev.071704.
8. Jacobs FMJ, van der Linden AJA, Wang Y, von Oerthel L, Sul HS, et al. (2009) Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons. Development 136: 2363-2373 doi:10.1242/dev.037556.
9. Marín F, Herrero M-T, Vyas S, Puelles L, (2005) Ontogeny of tyrosine hydroxylase mRNA expression in mid- and forebrain: neuromeric pattern and novel positive regions. Dev Dyn 234: 709-717 doi:10.1002/dvdy.20467.
10. Lahti L, Peltopuro P, Piepponen TP, Partanen J, (2012) Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain. Development 139: 894-905 doi:10.1242/dev.071936.
11. Joksimovic M, Anderegg A, Roy A, Campochiaro L, Yun B, et al. (2009) Spatiotemporally separable Shh domains in the midbrain define distinct dopaminergic progenitor pools. Proc Natl Acad Sci USA 106: 19185-19190 doi:10.1073/pnas.0904285106.
12. Blaess S, Bodea GO, Kabanova A, Chanet S, Mugniery E, et al. (2011) Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural Dev 6: 29 doi:--10.1186/1749-8104-6-29.
13. Smidt MP, Smits SM, Bouwmeester H, Hamers FPT, van der Linden AJA, et al. (2004) Early developmental failure of substantia nigra dopamine neurons in mice lacking the homeodomain gene Pitx3. Development 131: 1145-1155 doi:10.1242/dev.01022.
14. Jacobs FMJ, Smits SM, Noorlander CW, von Oerthel L, van der Linden AJA, et al. (2007) Retinoic acid counteracts developmental defects in the substantia nigra caused by Pitx3 deficiency. Development 134: 2673-2684 doi:10.1242/dev.02865.
15. Acampora D, Gulisano M, Simeone A, (1999) Otx genes and the genetic control of brain morphogenesis. Mol Cell Neurosci 13: 1-8 doi:10.1006/mcne.1998.0730.
16. Simeone A, (2000) Positioning the isthmic organizer where Otx2 and Gbx2meet. Trends Genet 16: 237-240.
17. Brodski C, Weisenhorn DMV, Signore M, Sillaber I, Oesterheld M, et al. (2003) Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer. J Neurosci 23: 4199-4207.
18. Smidt MP, Burbach JPH, (2007) How to make a mesodiencephalic dopaminergic neuron. Nat Rev Neurosci 8: 21-32 doi:10.1038/nrn2039.
19. Puelles L, Verney C, (1998) Early neuromeric distribution of tyrosine-hydroxylase-immunoreactive neurons in human embryos. J Comp Neurol 394: 283-308.
20. Ye W, Shimamura K, Rubenstein JL, Hynes MA, Rosenthal A, (1998) FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93: 755-766.
21. Hynes M, Rosenthal A, (1999) Specification of dopaminergic and serotonergic neurons in the vertebrate CNS. Curr Opin Neurobiol 9: 26-36.
22. Shults CW, Hashimoto R, Brady RM, Gage FH, (1990) Dopaminergic cells align along radial glia in the developing mesencephalon of the rat. Neuroscience 38: 427-436.
23. Hanaway J, McConnell JA, Netsky MG, (1970) Cytoarchitecture of the substantia nigra in the rat. Am J Anat 129: 417-437 doi:10.1002/aja.1001290404.
24. Kawano H, Ohyama K, Kawamura K, Nagatsu I, (1995) Migration of dopaminergic neurons in the embryonic mesencephalon of mice. Brain Res Dev Brain Res 86: 101-113.
25. Smits SM, Burbach JPH, Smidt MP, (2006) Developmental origin and fate of meso-diencephalic dopamine neurons. Prog Neurobiol 78: 1-16 doi:10.1016/j.pneurobio.2005.12.003.
26. Rubenstein JL, Martinez S, Shimamura K, Puelles L, (1994) The embryonic vertebrate forebrain: the prosomeric model. Science 266: 578-580.
27. Puelles L, Rubenstein JLR, (2003) Forebrain gene expression domains and the evolving prosomeric model. Trends Neurosci 26: 469-476 doi:--10.1016/S0166-2236(03)00234-0.
28. Jaeger CB, Teitelman G, Joh TH, Albert VR, Park DH, et al. (1983) Some neurons of the rat central nervous system contain aromatic-L-amino-acid decarboxylase but not monoamines. Science 219: 1233-1235.
29. Saucedo-Cardenas O, Quintana-Hau JD, Le WD, Smidt MP, Cox JJ, et al. (1998) Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons. Proc Natl Acad Sci USA 95: 4013-4018.
30. Bulfone A, Puelles L, Porteus MH, Frohman MA, Martin GR, et al. (1993) Spatially restricted expression of Dlx-1, Dlx-2 (Tes-1), Gbx-2, and Wnt-3 in the embryonic day 12.5 mouse forebrain defines potential transverse and longitudinal segmental boundaries. J Neurosci 13: 3155-3172.
31. Verney C, Zecevic N, Puelles L, (2001) Structure of longitudinal brain zones that provide the origin for the substantia nigra and ventral tegmental area in human embryos, as revealed by cytoarchitecture and tyrosine hydroxylase, calretinin, calbindin, and GABA immunoreactions. J Comp Neurol 429: 22-44.
32. Shimamura K, Hartigan DJ, Martinez S, Puelles L, Rubenstein JL, (1995) Longitudinal organization of the anterior neural plate and neural tube. Development 121: 3923-3933.
33. Wallén A, Zetterström RH, Solomin L, Arvidsson M, Olson L, et al. (1999) Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice. Exp Cell Res 253: 737-746 doi:10.1006/excr.1999.4691.
34. Simeone A, (1998) Otx1 and Otx2 in the development and evolution of the mammalian brain. EMBO J 17: 6790-6798 doi:10.1093/emboj/17.23.6790.
35. Vernay B, Koch M, Vaccarino F, Briscoe J, Simeone A, et al. (2005) Otx2 regulates subtype specification and neurogenesis in the midbrain. J Neurosci 25: 4856-4867 doi:-10.1523/JNEUROSCI.5158-04.2005.
36. Hanaway J, McConnell JA, Netsky MG, (1971) Histogenesis of the substantia nigra, ventral tegmental area of Tsai and interpeduncular nucleus: an autoradiographic study of the mesencephalon in the rat. J Comp Neurol 142: 59-73 doi:10.1002/cne.901420105.
37. Di Salvio M, Di Giovannantonio LG, Omodei D, Acampora D, Simeone A, (2010) Otx2 expression is restricted to dopaminergic neurons of the ventral tegmental area in the adult brain. Int J Dev Biol 54: 939-945 doi:10.1387/ijdb.092974ms.