Conservative initiation of antimicrobial treatment in ICU patients with suspected ICU-Acquired infection: More haste less speed

Current Opinion in Critical Care

Volumn 19, Issue 5, 2013, Pages 461-464

  Hranjec, Tjasa ^a   Sawyer, Robert G ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Antibiotic delay; Empiric antibiotic therapy; ICU Acquired infection; Sepsis

Indexed keywords

ANTIBIOTIC AGENT;

ANTIBIOTIC THERAPY; COMMUNITY ACQUIRED PNEUMONIA; CONSERVATIVE TREATMENT; DIAGNOSTIC ACCURACY; DISEASE SEVERITY; EMERGENCY WARD; HOSPITAL INFECTION; HUMAN; INTENSIVE CARE UNIT; LUNG INFECTION; OUTCOME ASSESSMENT; REVIEW; RISK ASSESSMENT; SEPSIS; SEPTIC SHOCK; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; CROSS INFECTION; DRUG ADMINISTRATION SCHEDULE; HUMANS; INTENSIVE CARE UNITS; TIME FACTORS;

EID: 84885022830     PISSN: 10705295     EISSN: 15317072     Source Type: Journal    
DOI: 10.1097/MCC.0b013e328364d525     Document Type: Review

References (5)

1. Spurling GK, Del Mar CB, Dooley L, et al. Delayed antibiotics for respiratory infections. Cochrane Database Syst Rev 2013; 4:CD004417.
2. Hranjec T, Rosenberger LH, Swenson BL, et al. Aggressive versus conservative initiation of antimicrobial treatment in critically ill surgical patients with suspected intensive-care-unit-Acquired infection: a quasi-experimental, before and after observational cohort study. Lancet Infect Dis 2012; 12:774-780.
3. Sucov A, Valente J, Reinert SE, et al. Time to first antibiotics for pneumonia is not associated with in-hospital mortality. J Emerg Med 2013; 45:1-7.
4. Puskarich MA, Trzeciak S, Shapiro SE, et al. Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol. Crit Care Med 2011; 39:2066-2071.
5. Vlek AL, Bonten MJ, Boel CH. Direct matrix-Assisted laser desorption ionization time-of-flight mass spectrometry improves appropriateness of antibiotic treatment of bacteremia. PLoS One 2012; 7:e32589.