메뉴 건너뛰기




Volumn 7, Issue 5, 2013, Pages 446-453

The influence of fenofibrate on lipid profile, endothelial dysfunction, and inflammatory markers in type 2 diabetes mellitus patients with typical and mixed dyslipidemia

Author keywords

Endothelial dysfunction; Fenofibrate; High density lipoprotein cholesterol; hsCRP; Low density lipoprotein; Noninvasive endothelial function assessments; Triglyceride; Vascular cell adhesion molecule 1

Indexed keywords

ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; C REACTIVE PROTEIN; FENOFIBRATE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84885019610     PISSN: 19332874     EISSN: 18764789     Source Type: Journal    
DOI: 10.1016/j.jacl.2013.04.004     Document Type: Article
Times cited : (20)

References (35)
  • 1
    • 33846154584 scopus 로고    scopus 로고
    • Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction
    • S.H. Han, M.J. Quon, and K.K. Koh Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction Curr Opin Lipidol 18 2007 58 65
    • (2007) Curr Opin Lipidol , vol.18 , pp. 58-65
    • Han, S.H.1    Quon, M.J.2    Koh, K.K.3
  • 3
    • 0034098951 scopus 로고    scopus 로고
    • Not acute but chronic hypertriglyceridemia is associated with impaired endothelium-dependent vasodilation: Reversal after lipid-lowering therapy by atorvasatatin
    • F.H. de Man, A.W. Weverling-Rijnsburger, A. van der Laarse, A.H. Smelt, J.W. Jukema, and G.J. Blauw Not acute but chronic hypertriglyceridemia is associated with impaired endothelium-dependent vasodilation: reversal after lipid-lowering therapy by atorvasatatin Atherioscler Thromb Vasc Biol 20 2000 744 750
    • (2000) Atherioscler Thromb Vasc Biol , vol.20 , pp. 744-750
    • De Man, F.H.1    Weverling-Rijnsburger, A.W.2    Van Der Laarse, A.3    Smelt, A.H.4    Jukema, J.W.5    Blauw, G.J.6
  • 4
    • 1042291190 scopus 로고    scopus 로고
    • Dylipidaemia management in adults with diabetes
    • American Diabetes Association (ADA)
    • American Diabetes Association (ADA) Dylipidaemia management in adults with diabetes Diabetes Care 27 2004 S68 S71
    • (2004) Diabetes Care , vol.27
  • 5
    • 0035909074 scopus 로고    scopus 로고
    • Hypertriglyceridemic hyper-apoB: The unappreciated atherogenic dyslipoproteinemia in type 2 diabetes mellitus
    • A.D. Sniderman, T. Scantlebury, and K. Cianflone Hypertriglyceridemic hyper-apoB: the unappreciated atherogenic dyslipoproteinemia in type 2 diabetes mellitus Ann Intern Med 135 2001 447 459
    • (2001) Ann Intern Med , vol.135 , pp. 447-459
    • Sniderman, A.D.1    Scantlebury, T.2    Cianflone, K.3
  • 6
    • 0031032831 scopus 로고    scopus 로고
    • Simvastatin, an HMG-Coenzyme A reductase Inhibitor, improves endothelial function within 1 month
    • G. O'Driscoll, D. Green, and R.R. Taylor Simvastatin, an HMG-Coenzyme A reductase Inhibitor, improves endothelial function within 1 month Circulation 95 1997 1126 1131
    • (1997) Circulation , vol.95 , pp. 1126-1131
    • O'Driscoll, G.1    Green, D.2    Taylor, R.R.3
  • 7
    • 0036632337 scopus 로고    scopus 로고
    • Aggressive lipid lowering does not improve endothelial function in type 2 diabetes: The diabetes atovarstatin lipid intervention (DALI) study: A randomized, double-blind, placebo-controlled trial
    • F.V. Venrooij, M.A. van dee Ree, and B.L. Mithcel Aggressive lipid lowering does not improve endothelial function in type 2 diabetes: The diabetes atovarstatin lipid intervention (DALI) study: a randomized, double-blind, placebo-controlled trial Diabetes Care 25 2002 1211 1216
    • (2002) Diabetes Care , vol.25 , pp. 1211-1216
    • Venrooij, F.V.1    Van Dee Ree, M.A.2    Mithcel, B.L.3
  • 8
    • 17944401657 scopus 로고    scopus 로고
    • Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus
    • M. Evans, R.A. Anderson, J. Graham, G.R. Ellis, K. Morris, and S. Davies Ciprofibrate therapy improves endothelial function and reduces postprandial lipemia and oxidative stress in type 2 diabetes mellitus Circulation 101 2000 1773 1779
    • (2000) Circulation , vol.101 , pp. 1773-1779
    • Evans, M.1    Anderson, R.A.2    Graham, J.3    Ellis, G.R.4    Morris, K.5    Davies, S.6
  • 9
    • 0034782457 scopus 로고    scopus 로고
    • Both fenofibrate and atorvastatin improve vascular reactivity in combined hyperlipidaemia (Fenofibrate versus Atorvastatin Trial: FAT)
    • J. Malik, V. Melenovsky, D. Wichterle, T. Haas, J. Simek, and R. Ceska Both fenofibrate and atorvastatin improve vascular reactivity in combined hyperlipidaemia (Fenofibrate versus Atorvastatin Trial: FAT) Cardiovasc Res 52 2001 290 298
    • (2001) Cardiovasc Res , vol.52 , pp. 290-298
    • Malik, J.1    Melenovsky, V.2    Wichterle, D.3    Haas, T.4    Simek, J.5    Ceska, R.6
  • 10
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study (DAIS)
    • Diabetes Atherosclerosis Intervention Study Investigators
    • Diabetes Atherosclerosis Intervention Study Investigators Effect of fenofibrate on progression of coronary artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study (DAIS) Lancet 357 2001 905 910
    • (2001) Lancet , vol.357 , pp. 905-910
  • 11
    • 19944379835 scopus 로고    scopus 로고
    • Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hyper TG
    • K.K. Koh, S.H. Han, M.J. Quon, J. Yeal Ahn, and E.K. Shin Beneficial effects of fenofibrate to improve endothelial dysfunction and raise adiponectin levels in patients with primary hyper TG Diabetes Care 28 2005 1419 1421
    • (2005) Diabetes Care , vol.28 , pp. 1419-1421
    • Koh, K.K.1    Han, S.H.2    Quon, M.J.3    Yeal Ahn, J.4    Shin, E.K.5
  • 12
    • 0032587240 scopus 로고    scopus 로고
    • The role of TNF-α and TNF-α receptors in obesity and insulin resistance
    • G.S. Hotamisligil The role of TNF-α and TNF-α receptors in obesity and insulin resistance J Intern Med 245 1999 621 626
    • (1999) J Intern Med , vol.245 , pp. 621-626
    • Hotamisligil, G.S.1
  • 13
    • 0033594810 scopus 로고    scopus 로고
    • PPAR-α activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells
    • N. Marx, G.K. Sukhova, T. Collins, P. Libby, and J. Plutzky PPAR-α activators inhibit cytokine-induced vascular cell adhesion molecule-1 expression in human endothelial cells Circulation 19 1999 3125 3131
    • (1999) Circulation , vol.19 , pp. 3125-3131
    • Marx, N.1    Sukhova, G.K.2    Collins, T.3    Libby, P.4    Plutzky, J.5
  • 14
    • 0033862040 scopus 로고    scopus 로고
    • Atorvastatin but not L-arginine improves endothelial function in type i diabetes mellitus: A double-blind study
    • M.J. Mullen, D. Wright, A.E. Donald, S. Thorne, H. Thomson, and J.E. Deanfield Atorvastatin but not L-arginine improves endothelial function in type I diabetes mellitus: a double-blind study J Am Coll Cardiol 36 2000 410 416
    • (2000) J Am Coll Cardiol , vol.36 , pp. 410-416
    • Mullen, M.J.1    Wright, D.2    Donald, A.E.3    Thorne, S.4    Thomson, H.5    Deanfield, J.E.6
  • 15
    • 0036040929 scopus 로고    scopus 로고
    • Effects of fibrates on serum metabolic parameters
    • M. Elisaf Effects of fibrates on serum metabolic parameters Curr Med Res Opin 18 2002 269 276
    • (2002) Curr Med Res Opin , vol.18 , pp. 269-276
    • Elisaf, M.1
  • 16
    • 76149092815 scopus 로고    scopus 로고
    • Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome
    • R. Belfort, R. Berria, J. Cornell, and K. Cusi Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome J Clin Endocrinol Metab 95 2010 829 836
    • (2010) J Clin Endocrinol Metab , vol.95 , pp. 829-836
    • Belfort, R.1    Berria, R.2    Cornell, J.3    Cusi, K.4
  • 17
    • 0015348189 scopus 로고
    • Estimation of the concentration of low density lipoprotein cholesterol in plasma without the use of the preparative ultracentrifuge
    • W.T. Friedewald, R.I. Levy, and D.S. Fredrickson Estimation of the concentration of low density lipoprotein cholesterol in plasma without the use of the preparative ultracentrifuge Clin Chem 18 1972 499 502
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 18
    • 0037116573 scopus 로고    scopus 로고
    • Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery. A report of the International Brachial Artery Reactivity Task Force
    • Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery. A report of the International Brachial Artery Reactivity Task Force J Am Coll Cardiol 39 2 2002 257 265
    • (2002) J Am Coll Cardiol , vol.39 , Issue.2 , pp. 257-265
  • 19
    • 0030854730 scopus 로고    scopus 로고
    • Endothelial dysfunction: Does it matter? Is it reversible?
    • D.S. Celermajer Endothelial dysfunction: does it matter? Is it reversible? J Am Coll Cardiol 30 1997 325 333
    • (1997) J Am Coll Cardiol , vol.30 , pp. 325-333
    • Celermajer, D.S.1
  • 20
    • 0029117715 scopus 로고
    • Non-invasive measurement of endothelium-dependent arterial responses in man: Accuracy and reproducibility
    • K.E. Sorensen, D.S. Celermajer, and D.J. Spiegelhalter Non-invasive measurement of endothelium-dependent arterial responses in man: accuracy and reproducibility Br Heart J 74 1995 247 253
    • (1995) Br Heart J , vol.74 , pp. 247-253
    • Sorensen, K.E.1    Celermajer, D.S.2    Spiegelhalter, D.J.3
  • 21
    • 0034975920 scopus 로고    scopus 로고
    • Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine
    • P. Lundman, M.J. Eriksson, M. Stühlinger, J.P. Cooke, A. Hamsten, and P. Tornvall Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine J Am Coll Cardiol 38 2001 111 116
    • (2001) J Am Coll Cardiol , vol.38 , pp. 111-116
    • Lundman, P.1    Eriksson, M.J.2    Stühlinger, M.3    Cooke, J.P.4    Hamsten, A.5    Tornvall, P.6
  • 22
    • 0037083222 scopus 로고    scopus 로고
    • Effect of insulin therapy on endothelium-dependent dilation in type 2 diabetes mellitus
    • H. Gaenzer, G. Neumayr, P. Marschang, W. Sturm, M. Lechleitner, and B. Föger Effect of insulin therapy on endothelium-dependent dilation in type 2 diabetes mellitus Am J Cardiol 89 2002 431 434
    • (2002) Am J Cardiol , vol.89 , pp. 431-434
    • Gaenzer, H.1    Neumayr, G.2    Marschang, P.3    Sturm, W.4    Lechleitner, M.5    Föger, B.6
  • 23
    • 0036890093 scopus 로고    scopus 로고
    • Effect of fenofibrate on brachial artery flow mediated dilation in Type 2 diabetes mellitus
    • D.A. Playford, G.F. Watts, J.D. Best, and V. Burke Effect of fenofibrate on brachial artery flow mediated dilation in Type 2 diabetes mellitus Am J Cardiol 90 2002 1254 1257
    • (2002) Am J Cardiol , vol.90 , pp. 1254-1257
    • Playford, D.A.1    Watts, G.F.2    Best, J.D.3    Burke, V.4
  • 24
    • 0033784645 scopus 로고    scopus 로고
    • Effects of comicronised fenofibrate on lipid and insulin sensitivity in patients with polymetabolic syndrome X
    • B. Idzior-Walus, J. Sieradzki, W. Rostworowski, A. Zdzienicka, E. Kawalec, and J. Wójcik Effects of comicronised fenofibrate on lipid and insulin sensitivity in patients with polymetabolic syndrome X Eur J Clin Invest 30 2000 871 878
    • (2000) Eur J Clin Invest , vol.30 , pp. 871-878
    • Idzior-Walus, B.1    Sieradzki, J.2    Rostworowski, W.3    Zdzienicka, A.4    Kawalec, E.5    Wójcik, J.6
  • 26
    • 0028864282 scopus 로고
    • Exercise-induced vasomotion of angiographically normal and stenotic coronary arteries improves after lipid lowering drugs therapy with bezafibrates
    • C. Seiler, T.M. Suter, and O.M. Hess Exercise-induced vasomotion of angiographically normal and stenotic coronary arteries improves after lipid lowering drugs therapy with bezafibrates J Am Coll Cardiol 26 1995 1615 1622
    • (1995) J Am Coll Cardiol , vol.26 , pp. 1615-1622
    • Seiler, C.1    Suter, T.M.2    Hess, O.M.3
  • 27
    • 0036301760 scopus 로고    scopus 로고
    • A novel mechanism for the beneficial vascular effects of high-density cholesterol enhanced vaso relaxation and increased endothelial nitric oxide synthase expression
    • J.T. Kuvin, M.E. Rämet, A.R. Patel, N.G. Pandian, M.E. Mendelsohn, and R.H. Karas A novel mechanism for the beneficial vascular effects of high-density cholesterol enhanced vaso relaxation and increased endothelial nitric oxide synthase expression Am Heart J 144 2002 165 172
    • (2002) Am Heart J , vol.144 , pp. 165-172
    • Kuvin, J.T.1    Rämet, M.E.2    Patel, A.R.3    Pandian, N.G.4    Mendelsohn, M.E.5    Karas, R.H.6
  • 28
    • 0038311032 scopus 로고    scopus 로고
    • Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein
    • R.J. Bisoendial, G.K. Hovingh, J.H. Levels, P.G. Lerch, I. Andresen, and M.R. Hayden Restoration of endothelial function by increasing high-density lipoprotein in subjects with isolated low high-density lipoprotein Circulation 107 2003 2944 2948
    • (2003) Circulation , vol.107 , pp. 2944-2948
    • Bisoendial, R.J.1    Hovingh, G.K.2    Levels, J.H.3    Lerch, P.G.4    Andresen, I.5    Hayden, M.R.6
  • 29
    • 33846992271 scopus 로고    scopus 로고
    • C-reactive protein and cardiovascular risk in metabolic syndrome and type 2 diabetes: Controversy and challenge
    • D.M. Capuzzi, and J.S. Freeman C-reactive protein and cardiovascular risk in metabolic syndrome and type 2 diabetes: controversy and challenge Clin Diabetes 25 2007 16 22
    • (2007) Clin Diabetes , vol.25 , pp. 16-22
    • Capuzzi, D.M.1    Freeman, J.S.2
  • 30
  • 31
    • 0036023622 scopus 로고    scopus 로고
    • High-sensitivity C-reactive protein and cardiovascular risk in patients with coronary heart disease
    • R.S. Rosenson, and W. Koenig High-sensitivity C-reactive protein and cardiovascular risk in patients with coronary heart disease Curr Opin Cardiol 17 2002 325 331
    • (2002) Curr Opin Cardiol , vol.17 , pp. 325-331
    • Rosenson, R.S.1    Koenig, W.2
  • 32
    • 0029841563 scopus 로고    scopus 로고
    • Elevated concentration of circulating adhesion molecule and their association with macrovascular complications in insulin dependent diabetes
    • P. Fasching, M. Veitl, M. Rohac, C. Streli, B. Schneider, and W. Waldhäusl Elevated concentration of circulating adhesion molecule and their association with macrovascular complications in insulin dependent diabetes J Clin Endocrinol Metabol 81 1996 4313 4318
    • (1996) J Clin Endocrinol Metabol , vol.81 , pp. 4313-4318
    • Fasching, P.1    Veitl, M.2    Rohac, M.3    Streli, C.4    Schneider, B.5    Waldhäusl, W.6
  • 34
    • 0028934872 scopus 로고
    • Low-density lipoprotein induces vascular adhesion molecule expression on human endothelial cells
    • H. Haller, D. Schaper, W. Ziegler, S. Philipp, M. Kuhlmann, and A. Distler Low-density lipoprotein induces vascular adhesion molecule expression on human endothelial cells Hypertension 25 1995 511 516
    • (1995) Hypertension , vol.25 , pp. 511-516
    • Haller, H.1    Schaper, D.2    Ziegler, W.3    Philipp, S.4    Kuhlmann, M.5    Distler, A.6
  • 35
    • 4143097037 scopus 로고    scopus 로고
    • Fenofibrate reduces TNF-α serum concentration and adipocyte secretion of hypercholesterolemic rabbits
    • S.P. Zhao, and J. Wu Fenofibrate reduces TNF-α serum concentration and adipocyte secretion of hypercholesterolemic rabbits Clin Chim Acta 347 2004 145 150
    • (2004) Clin Chim Acta , vol.347 , pp. 145-150
    • Zhao, S.P.1    Wu, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.