Submaximal heart and pulmonary evaluation: A novel noninvasive test to identify pulmonary hypertension in patients with systemic sclerosis

Arthritis Care and Research

Volumn 65, Issue 10, 2013, Pages 1713-1718

  Bernstein, Elana J ^a   Mandl, Lisa A ^a   Gordon, Jessica K ^a   Spiera, Robert F ^a   Horn, Evelyn M ^b  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b NEW YORK PRESBYTERIAN HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AZATHIOPRINE; CALCIUM CHANNEL BLOCKING AGENT; CORTICOSTEROID; CYCLOPHOSPHAMIDE; ENDOTHELIN RECEPTOR ANTAGONIST; ENOXAPARIN; HYDROXYCHLOROQUINE; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PHOSPHODIESTERASE V INHIBITOR; PROSTACYCLIN DERIVATIVE; WARFARIN;

ADULT; ARTICLE; CLINICAL ARTICLE; COHORT ANALYSIS; END TIDAL CARBON DIOXIDE TENSION; FEMALE; HEART CATHETERIZATION; HEART RIGHT ATRIUM PRESSURE; HUMAN; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; MALE; MEDICAL RECORD REVIEW; OXYGEN THERAPY; PREDICTIVE VALUE; PULMONARY HYPERTENSION; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SYSTEMIC SCLEROSIS;

AGED; ARTERIAL PRESSURE; CARDIAC CATHETERIZATION; EXERCISE TEST; FEMALE; HUMANS; HYPERTENSION, PULMONARY; LINEAR MODELS; LUNG; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS; PULMONARY ARTERY; PULMONARY DIFFUSING CAPACITY; RETROSPECTIVE STUDIES; SCLERODERMA, DIFFUSE; VITAL CAPACITY;

EID: 84885011416     PISSN: 2151464X     EISSN: 21514658     Source Type: Journal    
DOI: 10.1002/acr.22051     Document Type: Article

References (13)

1. Mukerjee D, St George D, Coleiro B, Knight C, Denton CP, Davar J, et al. Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach. Ann Rheum Dis 2003; 62: 1088-93.
2. Hachulla E, Gressin V, Guillevin L, Carpentier P, Diot E, Sibilia J, et al. Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study. Arthritis Rheum 2005; 52: 3792-800.
3. Steen VD, Medsger TA,. Changes in causes of death in systemic sclerosis, 1972-2002. Ann Rheum Dis 2007; 66: 940-4.
4. Bossone E, Duong-Wagner TH, Paciocco G, Oral H, Ricciardi M, Bach DS, et al. Echocardiographic features of primary pulmonary hypertension. J Am Soc Echocardiogr 1999; 12: 655-62.
5. Murata I, Takenaka K, Yoshinoya S, Kikuchi K, Kiuchi T, Tanigawa T, et al. Clinical evaluation of pulmonary hypertension in systemic sclerosis and related disorders: a Doppler echocardiographic study of 135 Japanese patients. Chest 1997; 111: 36-43.
6. Brecker SJ, Gibbs JS, Fox KM, Yacoub MH, Gibson DG,. Comparison of Doppler derived haemodynamic variables and simultaneous high fidelity pressure measurements in severe pulmonary hypertension. Br Heart J 1994; 72: 384-9.
7. Woods PR, Frantz RP, Taylor BJ, Olson TP, Johnson BD,. The usefulness of submaximal exercise gas exchange to define pulmonary arterial hypertension. J Heart Lung Transplant 2011; 30: 1133-42.
8. Miller AD, Woods PR, Olsen TP, Hulsebus ML, O'Malley KA, MacCarter D, et al. Validation of a simplified, portable cardiopulmonary gas exchange system for submaximal exercise testing. Open Sports Med J 2010; 4: 34-40.
9. Matsumoto A, Itoh H, Eto Y, Kobayashi T, Kato M, Omata M, et al. End-tidal CO2 pressure decreases during exercise in cardiac patients: association with severity of heart failure and cardiac output reserve. J Am Coll Cardiol 2000; 36: 242-9.
10. Yasunobu Y, Oudiz RJ, Sun XG, Hansen JE, Wasserman K,. End-tidal PCO2 abnormality and exercise limitation in patients with primary pulmonary hypertension. Chest 2005; 127: 1637-46.
11. Dumitrescu D, Oudiz RJ, Karpouzas G, Hovanesyan A, Jayasinghe A, Hansen JE, et al. Developing pulmonary vasculopathy in systemic sclerosis, detected with non-invasive cardiopulmonary exercise testing. PloS One 2010; 5: e14293.
12. Johnson SR, Granton JT,. Pulmonary hypertension in systemic sclerosis and systemic lupus erythematosus. Eur Respir Rev 2011; 20: 277-86.
13. Arena R, MacCarter D, Olson TP, Lalande S, Ceridon ML, Olson LJ, et al. Ventilatory expired gas at constant-rate low-intensity exercise predicts adverse events and is related to neurohormonal markers in patients with heart failure. J Card Fail 2009; 15: 482-8.