Effect of If-channel inhibition on hemodynamic status and exercise tolerance in heart failure with preserved ejection fraction: A randomized trial

Journal of the American College of Cardiology

Volumn 62, Issue 15, 2013, Pages 1330-1338

  Kosmala, Wojciech ^a   Holland, David J ^b   Rojek, Aleksandra ^a   Wright, Leah ^c   Przewlocka Kosmala, Monika ^a   Marwick, Thomas H ^c  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF TASMANIA   (Australia)

Author keywords

diastolic function; heart failure with preserved ejection fraction; ivabradine

Indexed keywords

IVABRADINE; PLACEBO; BENZAZEPINE DERIVATIVE; BRAIN NATRIURETIC PEPTIDE; CARDIOTONIC AGENT;

AGED; ARTICLE; BLOOD FLOW VELOCITY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MECHANISM; ECHOCARDIOGRAPHY; EXERCISE; EXERCISE TOLERANCE; FEMALE; HEART EJECTION FRACTION; HEART FAILURE; HEART FUNCTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE FILLING; HEART RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; OXYGEN CONSUMPTION; PRIORITY JOURNAL; DIASTOLE; DOPPLER ECHOCARDIOGRAPHY; DRUG EFFECTS; ECHOGRAPHY; EXERCISE TEST; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE PRESSURE; MITRAL VALVE; PHYSIOLOGY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; BNP; CI; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CORRELATION COEFFICIENT; DIASTOLIC FUNCTION; DRUG EFFECT; E′; HEART FAILURE WITH PRESERVED EJECTION FRACTION; HFPEF; I(F); ICC; INWARD " FUNNY"; LATE DIASTOLIC MITRAL FLOW VELOCITY; LEFT VENTRICULAR; LV; MET; METABOLIC EQUIVALENT; PEAK EARLY DIASTOLIC MITRAL ANNULAR VELOCITY; PEAK EARLY DIASTOLIC MITRAL FLOW VELOCITY; VO(2); WCCR; WORK LOAD-CORRECTED CHRONOTROPIC RESPONSE;

AGED; BENZAZEPINES; BLOOD FLOW VELOCITY; CARDIOTONIC AGENTS; DIASTOLE; DOUBLE-BLIND METHOD; ECHOCARDIOGRAPHY, DOPPLER, PULSED; EXERCISE TEST; EXERCISE TOLERANCE; FEMALE; HEART FAILURE; HEART RATE; HUMANS; MALE; MITRAL VALVE; NATRIURETIC PEPTIDE, BRAIN; OXYGEN CONSUMPTION; PROSPECTIVE STUDIES; VENTRICULAR FUNCTION, LEFT; VENTRICULAR PRESSURE;

BNP; BRAIN NATRIURETIC PEPTIDE; CI; CONFIDENCE INTERVAL; DIASTOLIC FUNCTION; E′; HEART FAILURE WITH PRESERVED EJECTION FRACTION; HFPEF; I(F); ICC; INTRACLASS CORRELATION COEFFICIENT; INWARD " FUNNY"; IVABRADINE; LATE DIASTOLIC MITRAL FLOW VELOCITY; LEFT VENTRICULAR; LV; MET; METABOLIC EQUIVALENT; OXYGEN UPTAKE; PEAK EARLY DIASTOLIC MITRAL ANNULAR VELOCITY; PEAK EARLY DIASTOLIC MITRAL FLOW VELOCITY; VO(2); WCCR; WORK LOAD-CORRECTED CHRONOTROPIC RESPONSE;

EID: 84885004398     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.06.043     Document Type: Article

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