IGF binding protein 2 is a cell-autonomous factor supporting survival and migration of acute leukemia cells

Journal of Hematology and Oncology

Volumn 6, Issue 1, 2013, Pages

  Chen, Xiaoli ^a   Zheng, Junke ^a   Zou, Yizhou ^a,b   Song, Chun ^c   Hu, Xuemei ^d   Zhang, Cheng Cheng ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b CENTRAL SOUTH UNIVERSITY   (China)

^c SHANDONG UNIVERSITY   (China)

^d BINZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INFILTRATION; CANCER TRANSPLANTATION; CARCINOGENESIS; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; WILD TYPE;

ANIMALS; APOPTOSIS; CELL MOVEMENT; CELL SURVIVAL; DISEASE MODELS, ANIMAL; HEK293 CELLS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, TRANSGENIC; SIGNAL TRANSDUCTION;

EID: 84884999455     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/1756-8722-6-72     Document Type: Article

References (41)

1. Acute myeloid leukemia. Appelbaum FR, Rowe JM, Radich J, Dick JE, Hematology Am Soc Hematol Educ Program 2001 62 86
2. Functional role of insulin-like growth factor binding proteins. Ranke MB, Elmlinger M, Horm Res 1997 48 Suppl 4 9 15 9350439
3. Insulin-like growth factor binding protein-2: contributions of the C-terminal domain to insulin-like growth factor-1 binding. Kibbey MM, Jameson MJ, Eaton EM, Rosenzweig SA, Mol Pharmacol 2006 69 833 845 16306230
4. Insulin-like growth factor-binding proteins in serum and other biological fluids: regulation and functions. Rajaram S, Baylink DJ, Mohan S, Endocr Rev 1997 18 801 831 10.1210/er.18.6.801 9408744
5. Cell membrane association of insulin-like growth factor binding protein-2 (IGFBP-2) in the rat brain olfactory bulb. Russo VC, Bach LA, Werther GA, Prog Growth Factor Res 1995 6 329 336 10.1016/0955-2235(95)00018-6 8817676
6. Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells. Schutt BS, Langkamp M, Rauschnabel U, Ranke MB, Elmlinger MW, J Mol Endocrinol 2004 32 859 868 10.1677/jme.0.0320859 15171717
7. Insulin-like growth factor binding protein 2 promotes glioma development and progression. Dunlap SM, Celestino J, Wang H, Jiang R, Holland EC, Fuller GN, Zhang W, Proc Natl Acad Sci U S A 2007 104 11736 11741 10.1073/pnas.0703145104 17606927
8. An interaction between insulin-like growth factor-binding protein 2 (IGFBP2) and integrin alpha5 is essential for IGFBP2-induced cell mobility. Wang GK, Hu L, Fuller GN, Zhang W, J Biol Chem 2006 281 14085 14091 10.1074/jbc.M513686200 16569642
9. Bimolecular interaction of insulin-like growth factor (IGF) binding protein-2 with alphavbeta3 negatively modulates IGF-I-mediated migration and tumor growth. Pereira JJ, Meyer T, Docherty SE, Reid HH, Marshall J, Thompson EW, Rossjohn J, Price JT, Cancer Res 2004 64 977 984 10.1158/0008-5472.CAN-03- 3056 14871828
10. Novel stimulatory role for insulin-like growth factor binding protein-2 in prostate cancer cells. Moore MG, Wetterau LA, Francis MJ, Peehl DM, Cohen P, Int J Cancer 2003 105 14 19 10.1002/ijc.11015 12672024
11. Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes. Wang H, Shen W, Huang H, Hu L, Ramdas L, Zhou YH, Liao WS, Fuller GN, Zhang W, Cancer Res 2003 63 4315 4321 12907597
12. Insulin-like growth factor-binding protein 2 in tumorigenesis: protector or promoter? Hoeflich A, Reisinger R, Lahm H, Kiess W, Blum WF, Kolb HJ, Weber MM, Wolf E, Cancer Res 2001 61 8601 8610 11751371
13. Role of insulin-like growth factor binding protein 2 in lung adenocarcinoma: IGF-independent antiapoptotic effect via caspase-3. Migita T, Narita T, Asaka R, Miyagi E, Nagano H, Nomura K, Matsuura M, Satoh Y, Okumura S, Nakagawa K, et al. Am J Pathol 2010 176 1756 1766 10.2353/ajpath.2010.090500 20150439
14. Insulin-like growth factor-binding protein contributes to the proliferation of less proliferative cells in forming skin equivalents. Kim DS, Cho HJ, Yang SK, Shin JW, Huh CH, Park KC, Tissue Eng Part A 2009 15 1075 1080 10.1089/ten.tea.2008.0236 18803482
15. IGFBP2 promotes glioma tumor stem cell expansion and survival. Hsieh D, Hsieh A, Stea B, Ellsworth R, Biochem Biophys Res Commun 2010 397 367 372 10.1016/j.bbrc.2010.05.145 20515648
16. Insulin-like growth factor binding protein-2 stimulates proliferation and activates multiple cascades of the mitogen-activated protein kinase pathways in NIH-OVCAR3 human epithelial ovarian cancer cells. Chakrabarty S, Kondratick L, Cancer Biol Ther 2006 5 189 197 10.4161/cbt.5.2.2333 16357519
17. Insulin-like growth factor binding proteins-2 and -4 enhance the migration of human CD34-/CD133+ hematopoietic stem and progenitor cells. Bartling B, Koch A, Simm A, Scheubel R, Silber RE, Santos AN, Int J Mol Med 2010 25 89 96 19956906
18. Insulin-like growth factor binding protein-2 binding to extracellular matrix plays a critical role in neuroblastoma cell proliferation, migration, and invasion. Russo VC, Schutt BS, Andaloro E, Ymer SI, Hoeflich A, Ranke MB, Bach LA, Werther GA, Endocrinology 2005 146 4445 4455 10.1210/en.2005-0467 15994346
19. IGF binding protein 2 supports the survival and cycling of hematopoietic stem cells. Huynh H, Zheng J, Umikawa M, Zhang C, Silvany R, Iizuka S, Holzenberger M, Zhang W, Zhang CC, Blood 2011 118 3236 3243 10.1182/blood-2011- 01-331876 21821709
20. Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-kappaB network. Holmes KM, Annala M, Chua CY, Dunlap SM, Liu Y, Hugen N, Moore LM, Cogdell D, Hu L, Nykter M, et al. Proc Natl Acad Sci U S A 2012 109 3475 3480 10.1073/pnas.1120375109 22345562
21. Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer. Mehrian-Shai R, Chen CD, Shi T, Horvath S, Nelson SF, Reichardt JK, Sawyers CL, Proc Natl Acad Sci U S A 2007 104 5563 5568 10.1073/pnas.0609139104 17372210
22. IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells. Perks CM, Vernon EG, Rosendahl AH, Tonge D, Holly JM, Oncogene 2007 26 5966 5972 10.1038/sj.onc.1210397 17369847
23. Insulin-like growth factor binding protein 2 (IGFBP-2) promotes growth and survival of breast epithelial cells: novel regulation of the estrogen receptor. Foulstone EJ, Zeng L, Perks CM, Holly JM, Endocrinology 2013 154 1780 1793 10.1210/en.2012-1970 23515291
24. IGFBP-2 enhances VEGF gene promoter activity and consequent promotion of angiogenesis by neuroblastoma cells. Azar WJ, Azar SH, Higgins S, Hu JF, Hoffman AR, Newgreen DF, Werther GA, Russo VC, Endocrinology 2011 152 3332 3342 10.1210/en.2011-1121 21750048
25. Distinct patterns of insulin-like growth factor binding protein (IGFBP)-2 and IGFBP-3 expression in oxidant exposed lung epithelial cells. Besnard V, Corroyer S, Trugnan G, Chadelat K, Nabeyrat E, Cazals V, Clement A, Biochim Biophys Acta 2001 1538 47 58 10.1016/S0167-4889(00)00136-1 11341982
26. Changes of serum growth factors (IGF-I,-II and IGFBP-2,-3) prior to and after stem cell transplantation in children with acute leukemia. Dawczynski K, Kauf E, Zintl F, Bone Marrow Transplant 2003 32 411 415 10.1038/sj.bmt.1704149 12900778
27. Insulin-like growth factor binding protein-2 at diagnosis of childhood acute lymphoblastic leukemia and the prediction of relapse risk. Vorwerk P, Mohnike K, Wex H, Rohl FW, Zimmermann M, Blum WF, Mittler U, J Clin Endocrinol Metab 2005 90 3022 3027 10.1210/jc.2004-0461 15687344
28. Identification of novel genes with prognostic value in childhood leukemia using cDNA microarray and quantitative RT-PCR. Hattori H, Matsuzaki A, Suminoe A, Koga Y, Tashiro K, Hara T, Pediatr Hematol Oncol 2006 23 115 127 10.1080/08880010500457780 16651240
29. Elevated serum insulin-like growth factor binding protein-2 is associated with a high relapse risk after hematopoietic stem cell transplantation in childhood AML. Dawczynski K, Kauf E, Schlenvoigt D, Gruhn B, Fuchs D, Zintl F, Bone Marrow Transplant 2006 37 589 594 10.1038/sj.bmt.1705281 16444283
30. Expression of components of the IGF axis in childhood acute myelogenous leukemia. Dawczynski K, Steinbach D, Wittig S, Pfaffendorf N, Kauf E, Zintl F, Pediatr Blood Cancer 2008 50 24 28 10.1002/pbc.21294 17635002
31. Insulin-like growth factor 2 and insulin-like growth factor binding protein 2 expression in hepatoblastoma. Akmal SN, Yun K, MacLay J, Higami Y, Ikeda T, Hum Pathol 1995 26 846 851 10.1016/0046-8177(95)90005-5 7543440
32. Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/SCID transplantation. Zhang CC, Kaba M, Iizuka S, Huynh H, Lodish HF, Blood 2008 111 3415 3423 10.1182/blood-2007-11-122119 18202223
33. GFBP2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells. Huynh H, LIizuka S, Kaba M, Kirak O, Zheng J, Lodish HF, Zhang CC, Stem Cells 2008 26 1628 1635 10.1634/stemcells.2008-0064 18369099
34. Global analysis of L1-transcriptomes identified IGFBP-2 as a target of ezrin and NF-kappaB signaling that promotes colon cancer progression. Ben-Shmuel A, Shvab A, Gavert N, Brabletz T, Ben-Ze'ev A, Oncogene 2013 32 3220 3230 10.1038/onc.2012.340 22869145
35. Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24. Fukushima T, Tezuka T, Shimomura T, Nakano S, Kataoka H, J Biol Chem 2007 282 18634 18644 10.1074/jbc.M609567200 17475624
36. PML-RARA can increase hematopoietic self-renewal without causing a myeloproliferative disease in mice. Welch JS, Yuan W, Ley TJ, J Clin Invest 2011 121 1636 1645 10.1172/JCI42953 21364283
37. AML1-ETO fusion protein up-regulates TRKA mRNA expression in human CD34+ cells, allowing nerve growth factor-induced expansion. Mulloy JC, Jankovic V, Wunderlich M, Delwel R, Cammenga J, Krejci O, Zhao H, Valk PJ, Lowenberg B, Nimer SD, Proc Natl Acad Sci U S A 2005 102 4016 4021 10.1073/pnas.0404701102 15731354
38. A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis. Yan M, Kanbe E, Peterson LF, Boyapati A, Miao Y, Wang Y, Chen IM, Chen Z, Rowley JD, Willman CL, Zhang DE, Nat Med 2006 12 945 949 10.1038/nm1443 16892037
39. Insulin-like growth factor-binding protein 2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells. Huynh H, Iizuka S, Kaba M, Kirak O, Zheng J, Lodish HF, Zhang CC, Stem Cells 2008 26 1628 1635 10.1634/stemcells.2008-0064 18369099
40. Inhibitory receptors bind Angptls and support blood stem cells and leukemia development. Zheng J, Umikawa M, Cui C, Li J, Chen X, Zhang CC, Huynh H, Kang X, Silvany R, Wan X, et al. Nature 2012 485 656 660 10.1038/nature11095 22660330
41. Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation. Zheng J, Umikawa M, Zhang S, Huynh H, Silvany R, Chen BP, Chen L, Zhang CC, Cell Stem Cell 2011 9 119 130 10.1016/j.stem.2011.06. 003 21816363