Predominance of Klebsiella pneumoniae ST14 carrying CTX-M-15 causing neonatal sepsis in Tanzania

BMC Infectious Diseases

Volumn 13, Issue 1, 2013, Pages

  Mshana, Stephen E ^a   Hain, Torsten ^b,d   Domann, Eugen ^b,d   Lyamuya, Eligius F ^c   Chakraborty, Trinad ^b,d   Imirzalioglu, Can ^b,d  

^a CATHOLIC UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c MUHIMBILI UNIVERSITY OF HEALTH AND ALLIED SCIENCES   (Tanzania)

^d German Center for Infection Research   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; BETA LACTAMASE CTX M; BETA LACTAMASE CTX M 15; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; COTRIMOXAZOLE; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; MEROPENEM; TETRACYCLINE; UNCLASSIFIED DRUG;

ALLELE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BLACTX-M 15 GENE; BLOOD ANALYSIS; BLOOD CULTURE; CONTROLLED STUDY; DISK DIFFUSION; DNA HYBRIDIZATION; ESBL GENE; GENE; GENE CLUSTER; GENE IDENTIFICATION; GENE LOCATION; GENE SEQUENCE; HETEROZYGOSITY; HUMAN; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MAJOR CLINICAL STUDY; MOLECULAR CLONING; MULTILOCUS SEQUENCE TYPING; NEWBORN; NEWBORN INTENSIVE CARE; NEWBORN SEPSIS; NONHUMAN; PHENOTYPE; PHYLOGENY; POLYMERASE CHAIN REACTION; PULSED FIELD GEL ELECTROPHORESIS; PUS; SEQUENCE HOMOLOGY; TANZANIA; URINALYSIS; WOUND ASSESSMENT;

BACTERIAL PROTEINS; BETA-LACTAMASES; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEPSIS; TANZANIA; TERTIARY CARE CENTERS;

EID: 84884998020     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-13-466     Document Type: Article

References (31)

1. Moyo SJ, Aboud S, Kasubi M, Lyamuya EF, Maselle SY. Antimicrobial resistance among producers and non-producers of extended spectrum beta-lactamases in urinary isolates at a tertiary Hospital in Tanzania. BMC Res Notes 2010, 3:348. 10.1186/1756-0500-3-348, 3017072, 21184671.
2. Mawalla B, Mshana SE, Chalya PL, Imirzalioglu C, Mahalu W. Predictors of surgical site infections among patients undergoing major surgery at Bugando Medical Centre in North-western Tanzania. BMC Surg 2011, 11(1):21. 10.1186/1471-2482-11-21, 3175437, 21880145.
3. Mshana SE, Imirzalioglu C, Hain T, Domann E, Lyamuya EF, Chakraborty T. Multiple ST clonal complexes, with a predominance of ST131, of Escherichia coli harbouring blaCTX-M-15 in a tertiary hospital in Tanzania. Clin Microbiol Infect 2011, 17(8):1279-1282. doi:10.1111/j.1469-0691.2011.03518.x, 10.1111/j.1469-0691.2011.03518.x, 21595794.
4. Bloomberg B, Jureen R, Manji KP, Tamim BS, Mwakagile DSM, Urassa WK, Fataki M, Msangi V, Tellevik M, Maselle SY, Langeland N. High Rate of Fatal Cases of Pediatric Septicemia Caused by Gram-Negative Bacteria with Extended-Spectrum Beta- Lactamases in Dar es Salaam. Tanzania J Clin Microbiol 2005, 43:745-749.
5. Ndugulile F, Jureen R, Harthug S, Urassa W, Langeland N. Extended Spectrum β-Lactamases among gram negative bacteria of nosocomial origin from an Intensive Care Unit of a Tertiary facility in Tanzania. BMC infect Dis 2005, 86:1471-2334.
6. Elihani D, Bakir L, Aouni M, Passet V, Arlet G, Brisse S, Weill FX. Molecular epidemiology of extended -spectrum beta-lactamase-producing Klebsiella pneumoniae strains in a university hospital in Tunis, Tunisia, 1999-2005. Clin Microbiol Infect 2010, 16(2):157-164. 10.1111/j.1469-0691.2009.03057.x, 19769601.
7. Carattoli A, Bertani A, Villa L, Falbo V, Kopkins LH, Threlfall EJ. Identification of plasmids by PCR- based replicon typing. J Microbiol Methods 2005, 63:219-228. 10.1016/j.mimet.2005.03.018, 15935499.
8. Karisik E, Ellington MJ, Pike R, Warren RE, Livermore DM, Woodford N. Molecular characterization of plasmids encoding CTX-M-15 β-lactamase from Escherichia coli strains in the United Kingdom. J Antimicrob Chemother 2006, 58:665-668. 10.1093/jac/dkl309, 16870648.
9. Mshana SE, Imirzalioglu C, Hossain H, Hain T, Domann E, Chakraborty T. Conjugative IncFI plasmids carrying CTX-M-15 among Escherichia coli ESBL producing isolates at a University hospital in Germany. BMC Infect Dis 2009, 9:97. 10.1186/1471-2334-9-97, 2708165, 19534775.
10. Paterson DL, Bonomo RA. Extended -spectrum β-lactamases: a clinical update. Clin Microbiol Rev 2005, 18:657-686. 10.1128/CMR.18.4.657-686.2005, 1265908, 16223952.
11. Damjanova I, Toth A, Paszti J, Hajbel-Vekony G, Jakab M, Berta J, Milch H, Fuzi M. Expansion and countrywide dissemination of ST11, ST15 and ST147 ciprofloxacin-resistant CTX-M-15-type beta-lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005-the new 'MRSAs'. J Antimicrob Chemother 2008, 62:978-985. 10.1093/jac/dkn287, 18667450.
12. Dumpis U, Inversen A, Balode A, Saule M, Miklasevics E, Giske CG. Outbreak of CTX-M-15-producing Klebsiella pneumoniae of sequence type 199 in a Latvian teaching hospital. APMIS 2010, 118:713-716. 10.1111/j.1600-0463.2010.02640.x, 20718724.
13. Kariuki S, Corkill JE, Revathi G, Musoke R, Harti CA. Molecular characterization of a novel plasmid-encoded cefotaximase (CTX-M-12) found in clinical Klebsiella pneumoniae isolates from Kenya. Antimicrob Agents Chemother 2001, 42:2141-2143.
14. Clinical and Laboratory Standards Institute Performance standards for antimicrobial disk susceptibility tests 2006, Wayne: PA, Approved standard. In Ninth edition Document M2-A9 Clinical and Laboratory Standards Institute, Clinical and Laboratory Standards Institute.
15. Menezes GA, Khan MA, Hays JP. Important methodological considerations with respect to differentiation of CTX-M-15 and CTX-M-28 extended-spectrum beta-lactamases. Indian J Med Microbiol 2010, 28:81-82. 10.4103/0255-0857.58743, 20061778.
16. Brisse S, van Himbergen T, Kusters K, Verhoef J. Development of a rapid identification method for Klebsiella pneumoniae phylogenetic groups and analysis of 420 clinical isolates. Clin Microbiol Infect 2004, 10:922-950. 10.1111/j.1469-0691.2004.00933.x, 15373888.
17. Diancourt L, Passet V, Verhoef J, Grimont PA, Brosse S. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol 2005, 43:4178-4182. 10.1128/JCM.43.8.4178-4182.2005, 1233940, 16081970.
18. Hirakata Y, Matsuda J, Miyazaki Y, Kamihira S, Kawakami S, Miyazawa Y. Regional variation in the prevalence of extended -spectrum; lactamase producing clinical isolates in the Asia-Pacific region (SENTRY 1998-2002). Diagn Microbiol Infect Dis 2005, 52:323-329. 10.1016/j.diagmicrobio.2005.04.004, 16165001.
19. Al-Agamy MH, Shibi AM, Tawfik AF. Prevalence and molecular characterization of extended-spectrum β Lactamase- producing Klebsiella pneumoniae in Riyadh. Saudi Arabia Ann Saudi Med 2009, 29:253-257.
20. Cassettari VC, da Silveira IR, Dropa M, Lincopan N, Mamizuka EM, Matte MH, Menezes PR. Risk factors for colonization of newborn infants during an outbreak of extended-spectrum β-lactamase-producing Klebsiella pneumoniae in an intermediate-risk neonatal unit. J Hosp Infect 2009, 71:340-347. 10.1016/j.jhin.2008.11.019, 19147256.
21. Harish BN, Menezes GA, Shekatkar S, Parija SC. Extended -spectrum beta-lactamase-producing Klebsiella pneumoniae from blood culture. J Med Microbiol 2007, 56:999-1000. 10.1099/jmm.0.47072-0, 17577070.
22. Miranda M, Natividad C, Leanos B, Valenzuela A, Garza-Ramos U, Rojas T, Solorzano F, Chihu L, Silva J. Clonal and Horizontal Dissemination of Klebsiella pneumoniae Expressing SHV-5 Extended-Spectrum β-Lactamase in a Mexican Pediatric Hospital. J Clin Microbiol 2004, 42:30-35. 10.1128/JCM.42.1.30-35.2004, 321705, 14715728.
23. Crivaro V, Bagattini M, Salza MF, Raimondi F, Rossano F, Triassi M, Zarrilli R. Risk factors for extended-spectrum β-lactamase-producing Serratia Marcescens and Klebsiella pneumoniae acquisition in a neonatal intensive care unit. J Hospital Infect 2007, 67:135-141.
24. Bedenic B, Goic-Baisic I, Tonic M, Mihajkevic LJ, Novak A, Sviben M, Plecko V, Punda-Polic V, Kalenic S. Antimicrobial susceptibility and beta-lactamase production of selected gram-negative bacilli from two Croatian hospitals: MYSTIC study results. J Chemother 2010, 22(3):147-152.
25. Oǧuz Mi{dotless}zrakç S, Arda B, Erdem HA, Uyar M, Tünger A, Sipahi OR, Ulusoy S. Risk factors for gastrointestinal colonization by ESBL-producing Klebsiella pneumoniae and Escherichia coli in anaesthesiology and reanimation intensive care unit. Mikrobiyol Bul 2013, 47(2):223-229. 10.5578/mb.4126, 23621722.
26. Vranic-Ladavac M, Bosnjak Z, Beader N, Barisic N, Kalenic S, Bedenic B. Clonal spread of CTX-M-15- producing Klebsiella pneumoniae in a Croatian hospital. J Med Microbiol 2010, 59:1069-1078. 10.1099/jmm.0.019778-0, 20576749.
27. Coelho A, Gonzalez-Lopez JJ, Miro E, Alonso-Tarres C, Mirelis B, Larrosa MN, Bartolome RM, Andreu A, Navarro F, Johnson JR, Prats G. Characterization of the CTX-M-15-encoding gene in Klebsiella pneumoniae strains from the Barcelona metropolitan area: plasmid diversity and chromosomal integration. Int J Antimicro Agents 2010, 36(1):73-10.
28. Dzierzanowska D, Kaminiska W, Semczuk K, Borowiec D, Matysiak M, Szumala-Kakol A, Gierczynski R, Patzer JA. Carriage of genes for various Extended-Spectrum β-Lactamases: a novel resistance strategy of Klebsiella pneumoniae in Poland. Int J Antimicrob Agents 2010, 35:392-395. 10.1016/j.ijantimicag.2009.12.010, 20138476.
29. Damjanova I, Toth A, Paszti J, Hajbel-Vekony G, Jakab M, Berta J, Milch H, Fuzi M. Expansion and countrywide dissemination of ST11, ST15 and ST147 ciprofloxacin -resistant CTX-M-15-type β-Lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005-the new MRSA. J Antimicrobial Chemother 2008, 62:978-985.
30. Oteo J, Cuevas O, Lopez Rodriguez I, Banderas Florido A, Vindel A, Perez Vazquez M, Bautista V, Arroyo M, Garcia-Caballero J, Marin Casanova P, Gonzalez Sanz R, Fuentes Gomez V, Ona Compan S, Garcia Cobos S, Campos J. Emergence of CTX-M-15 producing Klebsiella pneumoniae of multilocus sequence types 1, 11, 14, 17, 20, 35 and 36 as pathogens and colonizer in newborn and adults. J Antimicrob Chemother 2009, 64:524-528. 10.1093/jac/dkp211, 19525516.
31. Gray J, Arvelo W, McCracken J, Lopez B, Lessa FC, Kitchel B, Wong B, Reyes L, Lindblade K. An outbreak of Klebsiella pneumoniae late-onset sepsis in a neonatal intensive care unit in Guatemala. Am J Infect Control 2012, 40(6):516-520. 10.1016/j.ajic.2012.02.031, 22854378.