Biomarker or pathophysiology? the role of DNA methylation in postpartum depression

Epigenomics

Volumn 5, Issue 5, 2013, Pages 473-475

  Kimmel, Mary ^a   Kaminsky, Zachary ^a   Payne, Jennifer L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

biomarker; depression; DNA methylation; estrogen; postpartum

Indexed keywords

BIOLOGICAL MARKER; ESTRADIOL; ESTROGEN; PROGESTERONE;

BIPOLAR DISORDER; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DNA METHYLATION; DSM-5; DSM-IV; ENVIRONMENTAL FACTOR; GENETIC PREDISPOSITION; HUMAN; LYMPHOCYTE; MAJOR DEPRESSION; MONOCYTE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PUERPERAL DEPRESSION; PUERPERIUM; REVIEW; SLEEP DISORDER; FEMALE; GENETIC EPIGENESIS; METABOLISM;

BIOMARKERS; DEPRESSION, POSTPARTUM; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; HUMANS;

EID: 84884992129     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.13.51     Document Type: Review

References (16)

1. Camphcll SB, Cohn JF. Prcvalcnce and correlates of postpartum depression in first- time morhcrs.J. Abnorm. PsychoL 100(4), 594 599 (1992).
2. O'Hara MW. Postpartum dcprcssion: what wc know. J. (7/in. PsychoL 65(12), 1258 1269 (2009).
3. Dietz PM, Williams SB, Callaghan WM, Bachman DJ, Whitlock EP, Hornhrook MC. Clinically identified maternal depression before, during, and after prcgnancies cnding in livc births. Am.J. Psychiatry 164(10), 1515 1520 (2007).
4. Yonkcrs KA, Ramin SM, Rush AJ et al Onset and pcrsistence of postpartum deprcssion in an inncr-city maternal health clinic system. Am.J. Psychiatry 158(1 1), 1856 1863 (2001).
5. Paynej L, Roy PS, Murphy-Ehcrcnz K et al Reproductive cycle-associated mood symptoms in women with major dcprcssion and bipolar I disorder. j Affect. Disord. 99, 221 229 (2007).
6. Viguera AC, Tondo L, Koukopoulos AE, Rcginaldi D, Lepri B, Baldcssarini RJ. Episodes of mood disordcrs in 2,252 pregnancies and postpartum periods. Am.J. Psychiatry 168(1 1), 1179 85 (2011).
7. Forty L, Joncs L, Macgregor S et al. Familiality of postpartum dcprcssion in unipolar disordcr: results of a family study. Am.J. Psychiatry 163(9), 1549 53 (2006).
8. Murphy-Eherenz K, Zandi PP, March D et aL Is pcrinatal dcpression familial? J. Affect. Disord. 90(1), 49 55 (2006).
9. Paync JL, MacKinnon DF, Mondimore FM et al Familial aggregation of postpartum mood symptoms in families with bipolar disorder. 1. Bpo/arDisord. 10(1), 38 44 (2008).
10. Mahon PB, PaynejL, MacKinnon DF et al Genomc-widc linkage and follow-up association study of postpartum mood symptoms. Am. f Psychiatry 166(11), 1229 1237 (2009).
11. Bloch M, Schmidt U Danaceau M, Murphy J, Nicman L, Ruhinow DR. Effects of gonadal steroids in women with a history of postpartum dcpression. Am. J. Psychiatry 157(6), 924 930 (2000).
12. Guintivano J, Arad M, Gould TD, Payne JL, Kaminsky ZA. Antenatal prediction of postpartum dcprcssion with blood DNA methylation hiomarkers. 21/10/. Psychiatry doi:10.1038/mp.2013.62 (2013) (Epub ahcad of print).
13. Nassa G, Tarallo R, Ambrosino C et al. A largc set of estrogen receptor -intcracting proteins identified by tandem affinity purification in hormone-responsive human breast canccr cell nuclei. Proteomics 11, 159 165 (2011).
14. Cao S Iyer JK Lin V. Identification of tetratricopeptidc rcpcat domain 9 a Hormonally Rcgulatcd Protein. Biochem. Biophys. Res. Commun. 345 310 317 (2006).
15. Schmidt MV, Trumnhach D, Wcher P et al Individual strcss vulnerability is predictcd by short-tcrm memory and AMPA receptor subunit ratio in thc hippocampus. J. Neurosci. 30(50), 16949 16958 (2010).
16. Dcnnis CL, Dowswcll T. Psychosocial and psychological interventions for prcvcnting postpartum dcprcssion. Cochrane Database Syst. Rev. 2, CD001134 (2013).