Hierarchical model for evaluating pyrantel efficacy against strongyle parasites in horses

Veterinary Parasitology

Volumn 197, Issue 3-4, 2013, Pages 614-622

  Nielsen, M K ^a   Vidyashankar, A N ^b   Hanlon, B M ^c   Diao, G ^b   Petersen, S L ^d   Kaplan, R M ^e  

^a UNIVERSITY OF KENTUCKY   (United States)

^b George Mason University   (United States)

^c University of Wisconsin Madison   (United States)

^d Equilab Laboratory   (Denmark)

^e UNIVERSITY OF GEORGIA   (United States)

Author keywords

Anthelmintic resistance; Cyathostomin; Hierarchical models; Horses; Outliers; Pyrantel

Indexed keywords

PYRANTEL EMBONATE;

ANIMAL EXPERIMENT; ARTICLE; CLASSIFICATION; CONTROLLED STUDY; DENMARK; DRUG EFFICACY; DRUG RESISTANCE; FECES ANALYSIS; FEMALE; FIELD STUDY; HORSE; MALE; MATHEMATICAL ANALYSIS; MONTE CARLO METHOD; NONHUMAN; OBSERVATIONAL STUDY; PARASITE IDENTIFICATION; STATISTICAL ANALYSIS; STATISTICAL MODEL; STRONGYLE INFECTION; STRONGYLUS VULGARIS;

EQUIDAE; STRONGYLUS VULGARIS;

ANTHELMINTIC RESISTANCE; CYATHOSTOMIN; HIERARCHICAL MODELS; HORSES; OUTLIERS; PYRANTEL;

ANIMALS; ANTINEMATODAL AGENTS; COMPUTER SIMULATION; FECES; HORSES; MODELS, BIOLOGICAL; PYRANTEL; STRONGYLE INFECTIONS, EQUINE;

EID: 84884981811     PISSN: 03044017     EISSN: 18732550     Source Type: Journal    
DOI: 10.1016/j.vetpar.2013.04.036     Document Type: Article

References (29)

1. Coles G.C., Bauer C., Borgsteede F.H., Geerts S., Klei T.R., Taylor M.A., Waller P.J. World association for the advancement of veterinary parasitology (WAAVP) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet. Parasitol. 1992, 44:35-44.
2. Craven J., Bjørn H., Henriksen S.A., Nansen P., Larsen M., Lendal S. Survey of anthelmintic resistance on Danish horse farms, using 5 different methods of calculating faecal egg count reduction. Equine Vet. J. 1998, 30:289-293.
3. Cwiklinski K., Kooyman F.N.J., van Doorn D.C.K., Matthews J.B., Hodgkinson J.E. New insights into sequence variation in the IGS region of 21 cyathostomin species and the implication for molecular identification. Parasitology 2012, 139:1-11.
4. Drudge J.H., Lyons E.T. Methods in the evaluation of antiparasitic drugs in the horse. Am. J. Vet. Res. 1977, 38:1581-1586.
5. Drudge J.H., Lyons E.T., Tolliver S.C., Kubis J.E. Pyrantel in horses - clinical trials with emphasis on a paste formulation and activity on benzimidazole resistant small strongyles. Vet. Med. Small Anim. Clin. 1982, 77:956-967.
6. Fritzen B., Rohn K., Schnieder T., von Samson-Himmelstjerna G. Endoparasite control management on horse farms - lessons from worm prevalence and questionnaire data. Equine Vet. J. 2010, 42:79-83.
7. Herd R.P., Gabel A.A. Reduced efficacy of anthelmintics in young compared with adult horses. Equine Vet. J. 1990, 22:164-169.
8. Hodgkinson J.E., Lichtenfels J.R., Mair T.S., Cripps P., Freeman K.L., Ramsey Y.H., Love S., Matthews J.B. A PCR-ELISA for the identification of cyathostomin fourth-stage larvae from clinical cases of larval cyathostominosis. Int. J. Parasitol. 2003, 33:1427-1435.
9. Ihler C.F. A field survey on anthelmintic resistance in equine small strongyles in Norway. Acta Vet. Scand. 1995, 36:135-143.
10. Kaplan R.M. Drug resistance in nematodes of veterinary importance: a status report. Trends Parasitol. 2004, 20:477-481.
11. Kaplan R.M., Klei T.R., Lyons E.T., Lester G., Courtney C.H., French D.D., Tolliver S.C., Vidyashankar A.N., Zhao Y. Prevalence of anthelmintic resistant cyathostomes on horse farms. J. Am. Vet. Med. Assoc. 2004, 225:903-910.
12. Levecke B., Rinaldi L., Charlier J., Maurelli M.P., Morgoglione M.E., Vercruysse J., Cringoli G. Monitoring drug efficacy against gastrointestinal nematodes when faecal egg counts are low: do the analytic sensitivity and the formula matter?. Parasitol. Res. 2012, 109:953-957.
13. Levecke B., Rinaldi L., Charlier J., Maurelli M.P., Morgoglione M.E., Vercruysse J. The impact of baseline faecal egg counts on the efficacy of single-dose albendazole against Trichuris trichiura. Trans. R. Soc. Trop. Med. Hyg. 2012, 106:128-130.
14. Lichtenfels J.R., Kharchenko V.A., Dvojnos G.M. Illustrated identification keys to strongylid parasites (strongylidae: Nematoda) of horses, zebras and asses (equidae). Vet. Parasitol. 2008, 156:4-161.
15. Lind E.O., Kuzmina T., Uggla A., Waller P.J., Hoglund J. A field study on the effect of some anthelmintics on cyathostomins of horses in Sweden. Vet. Res. Commun. 2007, 31:53-65.
16. Lyons E.T., Drudge J.H., Tolliver S.C. Field tests of three salts of pyrantel [hydrochloride, tartrate, pamoate] against internal parasites of the horse [Strongylus vulgaris, Parascaris equorum, Strongylus edentatus]. Am. J. Vet. Res. 1975, 36:161-166.
17. Lyons E.T., Drudge J.H., Tolliver S.C. Antiparasitic activity of ivermectin in critical tests in equids. Am. J. Vet. Res. 1980, 41:2069-2072.
18. Matthews J.B., McArthur C., Robinson A., Jackson F. The in vitro diagnosis of anthelmintic resistance in cyathostomins. Vet. Parasitol. 2012, 186:25-31.
19. Morgan E.R., Cavill L., Curry G.E., Wood R.M., Mitchell E.S. Effects of aggregation and sample size on composite faecal egg counts in sheep. Vet. Parasitol. 2005, 131:79-87.
20. Morris C., Green R., Hickey S., Auldist M., Thomson N., Cullen N. Relationships among faecal egg counts, anti-parasite antibodies and milk yields in an experimental Friesian herd. New Zeal. J. Agric. Res. 2004, 47:267-274.
21. Nielsen M.K., Vidyashankar A.N., Andersen U.V., DeLisi K., Pilegaard K., Kaplan R.M. Effects of fecal collection and storage factors on strongylid egg counts in horses. Vet. Parasitol. 2010, 167:55-61.
22. Roepstorff A., Nansen P. Epidemiology, Diagnosis and Control Of Helminth Parasites of Swine 1998, Food and Agriculture Organization (FAO), Rome.
23. Russell A.F. The development of helminthiasis in thoroughbred foals. J. Comp. Pathol. Therap. 1948, 58:107-127.
24. Traversa D., Iorio R., Klei T.R., Kharchenko V.A., Gawor J., Otranto D., Sparagano O.A.E. New method for simultaneous species-specific identification of equine strongyles (nematoda, strongylida) by reverse line blot hybridization. J. Clin. Microbiol. 2007, 45:2937-2942.
25. Traversa D., von Samson-Himmelstjerna G., Demeler J., Milillo P., Schurmann S., Barnes H., Otranto D., Perrucci S., di Regalbono A.F., Beraldo P., Boeckh A., Cobb R. Anthelmintic resistance in cyathostomin populations from horse yards in Italy, United Kingdom and Germany. Parasit. Vector 2009, 2:S2.
26. Vermunt J.J., West D.M., Pomroy W.E. Inefficacy of moxidectin and doramectin against ivermectin-resistant Cooperia spp. of cattle in New Zealand. N Z Vet. J. 1996, 44:188-193.
27. Vidyashankar A.N., Hanlon B., Kaplan R.M. Statistical and biological considerations in evaluating drug efficacy in equine strongyle parasites using fecal egg count data. Vet. Parasitol. 2012, 185:45-57.
28. von Samson-Himmelstjerna G., Fritzen B., Demeler J., Schurmann S., Rohn K., Schnieder T., Epe C. Cases of reduced cyathostomin egg reappearance period and failure of Parascaris equorum egg count reduction following ivermectin treatment as well as survey on pyrantel efficacy on German horse farms. Vet. Parasitol. 2007, 144:74-80.
29. Wolstenholme A., Fairweather I., Prichard R., von Samson-Himmelstjerna G., Sangster N. Drug resistance in veterinary helminths. Trends Parasitol. 2004, 20:469-476.