Necrotizing Soft-Tissue Infections

Netter's Infectious Disease

Volumn , Issue , 2012, Pages 273-277

  Anaya, Daniel A ^a,b   Dellinger, E Patchen ^c,d  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84884974512     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-1-4377-0126-5.00048-3     Document Type: Chapter

References (12)

1. Anaya DA, Dellinger EP Necrotizing soft-tissue infection: diagnosis and management. Clin Infect Dis 2007, 44:705-710. This review encompasses all aspect of NSTI.
2. Ebright JR, Pieper B Skin and soft tissue infections in injection drug users. Infect Dis Clin North Am 2002, 16:697-712. This article reviews the increased risk and microbiologic characteristics of NSTI in intravenous drug users.
3. Green RJ, Dafoe DC, Raffin TA Necrotizing fasciitis. Chest 1996, 110:219-229. This is a comprehensive review of NSTI.
4. Pallin DJ, Egan DJ, Pelletier AJ, et al. Increased U.S. emergency department visits for skin and soft tissue infections, and changes in antibiotic choices, during the emergence of community-associated methicillin-resistant Staphylococcus aureus. Ann Emerg Med 2008, 51:291-298. This article goes over important epidemiologic and healthcare-burden aspects of soft-tissue infections within the United States.
5. Wall DB, Klein SR, Black S, de Virgilio C A simple model to help distinguish necrotizing fasciitis from nonnecrotizing soft tissue infection. J Am Coll Surg 2000, 191:227-231. This article identifies predictors of NSTI versus nonnecrotizing infections and develops a simple score to help establish the diagnosis.
6. Weiss KA, Laverdiere M Group A Streptococcus invasive infections: a review. Can J Surg 1997, 40:18-25. This review goes over the available data on epidemiology, pathophysiology, clinical presentation, treatment, and prognosis of group A Streptococcus infections, including those in the skin and soft tissues.
7. Anaya DA, Bulger EM, Kwong YS, et al. Predicting mortality in necrotizing soft tissue infections: a clinical score. Surg Infect (Larchmt) 2009, 10:517-522. This is the largest multiinstitutional study evaluating predictors of survival in NSTI. A clinical score was developed to stratify patients based on risk of death at the time of initial evaluation.
8. Anaya DA, McMahon K, Nathens AB, et al. Predictors of mortality and limb loss in necrotizing soft tissue infections. Arch Surg 2005, 140:151-157. discussion 158 This is one of the largest studies evaluating prognostic factors and determinants of adverse outcomes (mortality and/or limb amputation) in patients with NSTI. It also highlights the more severe course typically seen in patients with clostridial infections.
9. McHenry CR, Piotrowski JJ, Petrinic D, Malangoni MA Determinants of mortality for necrotizing soft-tissue infections. Ann Surg 1995, 221:558-563. discussion 563-565 This is a large study evaluating specific prognostic factors and determinants of mortality in patients with NSTI.
10. Miller LG, Perdreau-Remington F, Rieg G, et al. Necrotizing fasciitis caused by community-associated methicillin-resistant Staphylococcus aureus in Los Angeles. N Engl J Med 2005, 352:1445-1453. This study brings attention to the trend of increasing CA-MRSA infections, including those causing NSTI.
11. Singh G, Ray P, Sinha SK, et al. Bacteriology of necrotizing infections of soft tissues. Aust N Z J Surg 1996, 66:747-750. This study focuses on describing the nature (polymicrobial or monomicrobial) of and the most common microorganisms leading to NSTI.
12. Wong CH, Khin LW, Heng KS, et al. The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: a tool for distinguishing necrotizing fasciitis from other soft tissue infections. Crit Care Med 2004, 32:1535-1541. This is a large study that evaluates multiple potential predictors of NSTI and develops a much more elaborate and accurate score to help confirm (or rule out) the diagnosis of NSTI.