Endometrioma: From pathogenesis to clinical management

Journal of Endometriosis and Pelvic Pain Disorders

Volumn 5, Issue 3, 2013, Pages 91-99

  Luisi, Stefano ^a   Renner, Stefan P ^b   Santulli, Pietro ^c,d,e  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^e Section of Radiology   (France)

Author keywords

Dysmenorrhea; Endometrioma; Infertility; Inflammation; Laparoscopy; Medical therapy; Pelvic pain

Indexed keywords

CA 125 ANTIGEN; CYTOCHROME P450 2C19; DIENOGEST; OMEGA 3 FATTY ACID; ORAL CONTRACEPTIVE AGENT; ROUNDABOUT RECEPTOR;

CELL INFILTRATION; ECHOGRAPHY; EDITORIAL; ENDOMETRIUM TUMOR; FOLLOW UP; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; HISTOLOGY; HUMAN; INFERTILITY; INFLAMMATION; LAPAROSCOPIC SURGERY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOGENESIS; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENCE RISK; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84884927048     PISSN: 22840265     EISSN: 22840273     Source Type: Journal    
DOI: 10.5301/je.5000163     Document Type: Editorial

References (60)

1. Alborzi S, Zarei A, Alborzi S, Alborzi M. Management of ovarian endometrioma. Clin Obstet Gynecol. 2006; 49(3): 480-491.
2. Giudice LC. Clinical practice: endometriosis. N Engl J Med. 2010; 24(25): 2389-2398.
3. Van Holsbeke C, Van Calster B, Guerriero S, et al. Endometriomas: their ultrasound characteristics. Ultrasound Obstet Gynecol. 2010; 35(6): 730-740.
4. Burney RO, Giudice LC. Pathogenesis and pathophysiology of endometriosis. Fertil Steril. 2012; 98(3): 511-519.
5. Viganò P, Vanni VS, Corti L, et al. Unravelling the ovarian endometrioma pathogenesis: "the long and winding road" across the various theories. Journal of Endometriosis. 2013; 5(2): 62-67.
6. Hey-Cunningham AJ, Wei Ng F, Busard M, et al. Uterine lymphatic and blood micro-vessels in women with endometriosis through the menstrual. Journal of Endometriosis. 2010; 4: 197-205.
7. Khan KN, Kitajima M, Fujishita A, et al. Pelvic pain in women with ovarian endometrioma is mostly associated with coexisting peritoneal lesions. Hum Reprod. 2013; 28(1): 109-18.
8. Painter JN, Anderson CA, Nyholt DR, et al. Genome-wide association study identifies a locus at 7p15. 2 associated with endometriosis. Nat Genet. 2011; 43(1): 51-54.
9. Painter JN, Nyholt DR, Morris A, et al. High-density finemapping of a chromosome 10q26 linkage peak suggests association between endometriosis and variants close to CYP2C19. Fertil Steril. 2011; 95(7): 2236-2240.
10. Pagliardini L, Gentilini D, Vigano' P, et al. An Italian association study and meta-analysis with previous GWAS confirm WNT4, CDKN2BAS and FN1 as the first identified susceptibility loci for endometriosis. J Med Genet. 2013; 50(1): 43-46.
11. Borghese B, Santulli P, Héquet D, et al. Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis. Am J Pathol. 2012; 180(5): 1781-1786.
12. Shen F, Liu X, Geng JG, Guo SW. Increased immunoreactivity to SLIT/ROBO1 in ovarian endometriomas: a likely constituent biomarker for recurrence. Am J Pathol. 2009; 175(2): 479-488.
13. Taylor RN, Yu J, Torres PB, et al. Mechanistic and therapeutic implications of angiogenesis in endometriosis. Reprod Sci. 2009; 16(2): 140-146.
14. Carmona F, Martinez-Zamora A, Bassols ML, Balasch J. Environmental influences on the development of endometriosis. Journal of Endometriosis. 2013; 5(2): 49-61.
15. Bruner-Tran KL, Osteen KG. Dioxin-like PCBs and endometriosis. Syst Biol Reprod Med. 2010; 56(2): 132-146.
16. Borghese B, Santulli P, Vaiman D, Alexandre J, Goldwasser F, Chapron C. [Endometriosis-associated ovarian cancers: pathogenesis and consequences on daily practice] [article in French]. J Gynecol Obstet Biol Reprod (Paris). 2013; 42(4): 325-333.
17. Burghaus SKP, Fasching PA, Engel A, et al. Risk factors for endometriosis in a German case-control study. Geburtshilfe Frauenheilkd. 2011; 71(12): 1073-1079.
18. Busacca M, Vignali M. Endometrioma excision and ovarian reserve: a dangerous relation. J Minim Invasive Gynecol. 2009; 16(2): 142-148.
19. Fauconnier A, Chapron C. Endometriosis and pelvic pain: epidemiological evidence of the relationship and implications. Hum Reprod Update. 2005; 11(6): 595-606.
20. Exacoustos C, Zupi E, Carusotti C, et al. Staging of pelvic endometriosis: role of sonographic appearance in determining extension of disease and modulating surgical approach. J Am Assoc Gynecol Laparosc. 2003; 10(3): 378-382.
21. May KE, Conduit-Hulbert SA, Villar J, Kirtley S, Kennedy SH, Becker CM. Peripheral biomarkers of endometriosis: a systematic review. Hum Reprod Update. 2010; 16(6): 651-674.
22. Kurdoglu Z, Gursoy R, Kurdoglu M, Erdem M, Erdem O, Erdem A. Comparison of the clinical value of CA 19-9 versus CA 125 for the diagnosis of endometriosis. Fertil Steril. 2009; 92(5): 1761-1763.
23. Vodolazkaia A, El-Aalamat Y, Popovic D, et al. Evaluation of a panel of 28 biomarkers for the non-invasive diagnosis of endometriosis. Hum Reprod. 2012; 27(9): 2698-2711.
24. Fassbender A, Waelkens E, Verbeeck N, et al. Proteomics analysis of plasma for early diagnosis of endometriosis. Obstet Gynecol. 2012; 119(2 Pt 1): 276-285.
25. Vercellini P, Crosignani PG, Abbiati A, Somigliana E, Viganò P, Fedele L. The effect of surgery for symptomatic endometriosis: the other side of the story. Hum Reprod Update. 2009; 15(2): 177-188.
26. de Ziegler D, Borghese B, Chapron C. Endometriosis and infertility: pathophysiology and management. Lancet. 2010; 376(9742): 730-738.
27. Dubernard G, Rouzier R, David-Montefiore E, Bazot M, Daraï E. Urinary complications after surgery for posterior deep infiltrating endometriosis are related to the extent of dissection and to uterosacral ligaments resection. J Minim Invasive Gynecol. 2008; 15(2): 235-240.
28. Streuli I, de Ziegler D, Gayet V, et al. In women with endometriosis anti-Müllerian hormone levels are decreased only in those with previous endometrioma surgery. Hum Reprod. 2012; 27(11): 3294-3303.
29. Raffi F, Metwally M, Amer S. The impact of excision of ovarian endometrioma on ovarian reserve: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2012; 97(9): 3146-3154.
30. Chapron C, Pietin-Vialle C, Borghese B, Davy C, Foulot H, Chopin N. Associated ovarian endometrioma is a marker for greater severity of deeply infiltrating endometriosis. Fertil Steril. 2009; 92(2): 453-457.
31. Donnez J, Squifflet J, Donnez O. Minimally invasive gynecologic procedures. Curr Opin Obstet Gynecol. 2011; 23(4): 289-295.
32. Muzii L. Surgery for the endometrioma and ovarian reserve: is it a real damage? Journal of Endometriosis. 2012; 4: 209.
33. Muzii L, Marana R, Angioli R, et al. Histologic analysis of specimens from laparoscopic endometrioma excision performed by different surgeons: does the surgeon matter? Fertil Steril. 2011; 95(6): 2116-2119.
34. Donnez J, Lousse JC, Jadoul P, Donnez O, Squifflet J. Laparoscopic management of endometriomas using a combined technique of excisional (cystectomy) and ablative surgery. Fertil Steril. 2010; 94(1): 28-32.
35. Muzii L, Bellati F, Palaia I, et al. Laparoscopic stripping of endometriomas: a randomized trial on different surgical techniques. Part I: clinical results. Hum Reprod. 2005; 20(7): 1981-1986.
36. Guo SW. Recurrence of endometriosis and its control. Hum Reprod Update. 2009; 15(4): 441-461.
37. Hudelist G, Oberwinkler KH, Singer CF, et al. Combination of transvaginal sonography and clinical examination for preoperative diagnosis of pelvic endometriosis. Hum Reprod. 2009; 24(5): 1018-1024.
38. Taylor E, Williams C. Surgical treatment of endometriosis: location and patterns of disease at reoperation. Fertil Steril. 2010; 93(1): 57-61.
39. Exacoustos C, Zupi E, Amadio A, et al. Recurrence of endometriomas after laparoscopic removal: sonographic and clinical follow-up and indication for second surgery. J Minim Invasive Gynecol. 2006; 13(4): 281-288.
40. Wattiez A, Puga M, Albornoz J, Faller E. Surgical strategy in endometriosis. Best Pract Res Clin Obstet Gynaecol. 2013; 27(3): 381-392.
41. Strowitzki T, Marr J, Gerlinger C, Faustmann T, Seitz C. Dienogest is as effective as leuprolide acetate in treating the painful symptoms of endometriosis: a 24-week, randomized, multicentre, open-label trial. Hum Reprod. 2010; 25(3): 633-641.
42. Köhler G, Faustmann TA, Gerlinger C, Seitz C, Mueck AO. A dose-ranging study to determine the efficacy and safety of 1, 2, and 4 mg of dienogest daily for endometriosis. Int J Gynaecol Obstet. 2010; 108(1): 21-25.
43. Strowitzki T, Faustmann T, Gerlinger C, Seitz C. Dienogest in the treatment of endometriosis-associated pelvic pain: a 12-week, randomized, double-blind, placebo-controlled study. Eur J Obstet Gynecol Reprod Biol. 2010; 151(2): 193-198.
44. Petraglia F, Hornung D, Seitz C, et al. Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment. Arch Gynecol Obstet. 2012; 285(1): 167-173.
45. Strowitzki T, Marr J, Gerlinger C, Faustmann T, Seitz C. Detailed analysis of a randomized, multicenter, comparative trial of dienogest versus leuprolide acetate in endometriosis. Int J Gynaecol Obstet. 2012; 117(3): 228-233.
46. Harada T, Momoeda M, Taketani Y, et al. Dienogest is as effective as intranasal buserelin acetate for the relief of pain symptoms associated with endometriosis: a randomized, double-blind, multicenter, controlled trial. Fertil Steril. 2009; 91(3): 675-681.
47. Momoeda M, Harada T, Terakawa N, et al. Long-term use of dienogest for the treatment of endometriosis. J Obstet Gynaecol Res. 2009; 35(6): 1069-1076.
48. Seracchioli R, Mabrouk M, Frascà C, et al. Long-term cyclic and continuous oral contraceptive therapy and endometrioma recurrence: a randomized controlled trial. Fertil Steril. 2010; 93(1): 52-56.
49. Vercellini P, Somigliana E, Daguati R, et al. Postoperative oral contraceptive exposure and risk of endometrioma recurrence. Am J Obstet Gynecol. 2008; 198(504): 501-505.
50. Lee DY, Bae DS, Yoon BK, Choi D. Post-operative cyclic oral contraceptive use after gonadotrophin-releasing hormone agonist treatment effectively prevents endometrioma recurrence. Hum Reprod. 2010; 25(12): 3050-3054.
51. Takamura M, Koga K, Osuga Y, et al. Post-operative oral contraceptive use reduces the risk of ovarian endometrioma recurrence after laparoscopic excision. Hum Reprod. 2009; 24(12): 3042-3048.
52. Novembri R, Luisi S, Carrarelli P, Ciani V, De Pascalis F, Petraglia F. Omega 3 fatty acids counteract IL-8 and prostaglandin E2 secretion induced by TNF-22in cultured endometrial stromal cells. Journal of Endometriosis. 2011; 1: 34-40.
53. Falconer H, Sundqvist J, Gemzell-Danielsson K, von Schoultz B, D'Hooghe TM, Fried G. IVF outcome in women with endometriosis in relation to tumour necrosis factor and anti-Müllerian hormone. Reprod Biomed Online. 2009; 18(4): 582-588.
54. May KE, Villar J, Kirtley S, Kennedy SH, Becker CM. Endometrial alterations in endometriosis: a systematic review of putative biomarkers. Hum Reprod Update. 2011; 17(5): 637-653.
55. Rocha AL, Carrarelli P, Novembri R, et al. Activin A stimulates interleukin 8 and vascular endothelial growth factor release from cultured human endometrial stromal cells: possible implications for the pathogenesis of endometriosis. Reprod Sci. 2012; 19(8): 832-838.
56. Rocha AL, Carrarelli P, Novembri R, et al. Altered expression of activin, cripto, and follistatin in the endometrium of women with endometrioma. Fertil Steril. 2011; 95(7): 2241-2246.
57. Novembri R, Carrarelli P, Toti P, et al. Urocortin 2 and urocortin 3 in endometriosis: evidence for a possible role in inflammatory response. Mol Hum Reprod. 2011; 17(9): 587-593.
58. Noël JC, Anaf V, Borghese B, Vaiman D, Fayt I, Chapron C. The steroidogenic factor-1 protein is not expressed in various forms of endometriosis but is strongly present in ovarian cortical or medullary mesenchymatous cells adjacent to endometriotic foci. Fertil Steril. 2011; 95(8): 2655-2657.
59. Elizur SE, Chian RC, Holzer HE, Gidoni Y, Tulandi T, Tan SL. Cryopreservation of oocytes in a young woman with severe and symptomatic endometriosis: a new indication for fertility preservation. Fertil Steril. 2009; 91(1): e1-e3.
60. Rienzi L, Cobo A, Paffoni A, et al. Consistent and predictable delivery rates after oocyte vitrification: an observational longitudinal cohort multicentric study. Hum Reprod. 2012; 27(6): 1606-1612.