Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: Evidence for on-demand biosynthesis of 2-arachidonoylglycerol

Journal of Physiology

Volumn 591, Issue 19, 2013, Pages 4765-4776

  Hashimotodani, Yuki ^a   Ohno Shosaku, Takako ^c   Tanimura, Asami ^a   Kita, Yoshihiro ^a,b   Sano, Yoshikazu ^a   Shimizu, Takao ^a,b   Di Marzo, Vincenzo ^d   Kano, Masanobu ^a  

^a Department of Neurophysiology ^*  (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

^d CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 ARACHIDONOYLGLYCEROL; CALCIUM ION; CANNABINOID 1 RECEPTOR; DIACYLGLYCEROL LIPASE ALPHA; ENDOCANNABINOID; ENZYME INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; LIPOPROTEIN LIPASE; METABOTROPIC RECEPTOR 1; OMDM 188; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CALCIUM TRANSPORT; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DEPOLARIZATION; FEMALE; HIPPOCAMPUS; MOUSE; NERVE CELL; NEWBORN; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRIORITY JOURNAL; PURKINJE CELL; RAT; SYNAPSE; SYNAPTIC TRANSMISSION;

ANIMALS; ARACHIDONIC ACIDS; BRAIN; CALCIUM; ENDOCANNABINOIDS; GLYCERIDES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; ISOLEUCINE; LACTONES; LIPOPROTEIN LIPASE; MICE; MICE, INBRED C57BL; PURKINJE CELLS; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 84884924686     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.254474     Document Type: Article

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