Production of 4-hydroxybutyric acid by metabolically engineered Mannheimia succiniciproducens and its conversion to γ-butyrolactone by acid treatment

Metabolic Engineering

Volumn 20, Issue , 2013, Pages 73-83

  Choi, Sol ^a   Kim, Hyun Uk ^a   Kim, Tae Yong ^a   Kim, Won Jun ^a   Lee, Moon Hee ^a   Lee, Sang Yup ^a  

^a Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

4 Hydroxybutyric acid; C4 chemicals; Mannheimia succiniciproducens; Metabolic engineering; Succinic acid; Butyrolactone

Indexed keywords

BATCH CELL CULTURE; INDUSTRIAL APPLICATIONS; METABOLIC ENGINEERING;

BUTYROLACTONES; FED-BATCH CULTURES; FERMENTATION BROTHS; MANNHEIMIA SUCCINICIPRODUCENS; METABOLIC PATHWAYS; PLATFORM CHEMICALS; SEMIALDEHYDE DEHYDROGENASE; SUCCINIC ACIDS;

CARBON;

4 HYDROXYBUTYRATE DEHYDROGENASE; 4 HYDROXYBUTYRIC ACID; BACTERIAL ENZYME; COENZYME A; GAMMA BUTYROLACTONE; OXIDOREDUCTASE; PYRUVATE KINASE 7; SUCCINATE SEMIALDEHYDE DEHYDROGENASE; SUCCINIC ACID; SUCCINYL COENZYME A SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CARBON METABOLISM; CONTROLLED STUDY; FED BATCH CULTURE; FERMENTATION; MANNHEIMIA SUCCINICIPRODUCENS; METABOLIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; RUMEN MICROORGANISM;

BACTERIA (MICROORGANISMS); MANNHEIMIA SUCCINICIPRODUCENS;

4-HYDROXYBUTYRIC ACID; C4 CHEMICALS; MANNHEIMIA SUCCINICIPRODUCENS; METABOLIC ENGINEERING; SUCCINIC ACID; Γ-BUTYROLACTONE;

4-BUTYROLACTONE; BACTERIAL PROTEINS; HYDROXYBUTYRATES; MANNHEIMIA; METABOLIC ENGINEERING; MUTATION;

EID: 84884918887     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2013.09.001     Document Type: Article

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